A5038996586- Peripheral Neuropathies and Disorders
- Botulinum Toxin and Related Neurological Disorders
- Hereditary Neurological Disorders
- Pain Mechanisms and Treatments
- Mosquito-borne diseases and control
- Neurogenetic and Muscular Disorders Research
- Leprosy Research and Treatment
- Peripheral Nerve Disorders
- Parkinson's Disease Mechanisms and Treatments
- Epilepsy research and treatment
- Amyotrophic Lateral Sclerosis Research
- Pharmacological Effects and Toxicity Studies
- Neurological and metabolic disorders
- Multiple Sclerosis Research Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Genetic Neurodegenerative Diseases
- Musculoskeletal pain and rehabilitation
- Viral Infections and Vectors
- Glycogen Storage Diseases and Myoclonus
- Nerve Injury and Rehabilitation
- Lysosomal Storage Disorders Research
- Infectious Diseases and Tuberculosis
- Long-Term Effects of COVID-19
- Cerebral Palsy and Movement Disorders
- Orthopedic Surgery and Rehabilitation
Universidade Federal Fluminense
2016-2025
Hospital Universitário Antônio Pedro
2014-2025
Brazilian Academy of Sciences
2024
Universidade Federal do Estado do Rio de Janeiro
2013-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2024
Universidade de São Paulo
2006-2021
Brazilian National Association of Graduate Programs in Communication
2021
Universidade Federal do Rio de Janeiro
1985-2020
Neurology, Inc
2020
Universidade do Estado do Rio de Janeiro
2018-2019
There are no prospective cohort studies assessing the incidence and spectrum of neurologic manifestations secondary to Zika virus (ZIKV) infection in adults.To evaluate rates acute ZIKV among patients hospitalized with Guillain-Barré syndrome (GBS), meningoencephalitis, or transverse myelitis.A prospective, observational study was conducted at a tertiary referral center for neurological diseases Rio de Janeiro, Brazil, between December 5, 2015, May 10, 2016, consecutive adults (>18 years...
Varicella-zoster virus (VZV) is a human neurotropic that remains in latent state within ganglionic neurons throughout the entire neuroaxis after primary infection. When herpes zoster (HZ) leads to trigeminal involvement, ophthalmic division most implicated. COVID-19 has emerged as viral cause of severe acute respiratory syndrome spread all over world last months. Co-infection with and other viruses been reported, but sparsely, involving viruses.The case co-infection VZV literature reviewed.A...
There has been a significant increase over recent years in the use of contact heat evoked potentials (CHEPs) for evaluation small nerve fiber function. Measuring CHEP amplitude and latency clinical utility diagnosis assessment conditions with neuropathic pain. This international multicenter study aimed to provide reference values CHEPs stimuli at 5 commonly examined body sites. Contact were recorded from 226 subjects (114 females), distributed per age decade between 20 79 years. Temperature...
Congenital Zika syndrome virus infection is said to interfere in children's development.evaluate gross motor trajectories and the frequency of cerebral palsy children with congenital syndrome.Cohort study applying Alberta Infant Motor Scale (AIMS) Bayley III Scales infants from 6 18 months age.The SARAH network, Rio de Janeiro.Thirty-nine whose diagnoses were established through clinical history, serology tests, neuroimaging findings. Main outcomes measures: associated severe delays a risk...
ABSTRACT The expanding therapeutic arsenal in multiple sclerosis (MS) has allowed for more effective and personalized treatment, but the choice management of disease-modifying therapies (DMTs) is becoming increasingly complex. In this context, experts from Brazilian Committee on Treatment Research Multiple Sclerosis Neuroimmunology Scientific Department Academy Neurology have convened to establish Consensus MS, based their understanding that neurologists should be able prescribe MS DMTs...
BACKGROUND AND OBJECTIVES: Diabetic neuropathy is a major cause of worldwide and may lead to amputations incapacity. This study aimed at detailed updated review on diabetic neuropathy, focusing its classification, diagnostic investigation treatment. CONTENTS: It estimated that 371 million people aged from 20 79 years, worldwide, have diabetes mellitus least half them are unware the diagnosis. Its prevalence in Central South America was 26.4 people, corresponding approximately 6.5%...
Introduction: Persistent spinal pain syndrome (PSPS) type 2 is a chronic condition characterized by low back pain, with or without radiating limb persisting after surgery. The underlying pathophysiology remains unclear, potential contributions from altered central processing mechanisms. Objective: This study investigates the role of sensitization in PSPS using contact heat-evoked potentials (CHEPs), an electrophysiological tool for assessing spinothalamic tract integrity and processing....
Abstract Background Charcot-Marie-Tooth (CMT) disease is a genetically diverse group of hereditary neuropathies. Most studies on the frequency CMT subtypes report that early growth response 2 (EGR2) gene accounts for less than 1% cases. However, data regarding epidemiology and clinical characteristics EGR2-related in Central South America remain limited. Objective To characterize genetic features Brazilian cohort. Methods We retrospectively analyzed ancillary from four individuals with...
Multidrug therapy (MDT), with rifampicin, dapsone, and clofazimine, treats leprosy infection but is insufficient in arresting or preventing the nerve damage that causes impairments disabilities. This case-series study evaluates benefits of combined use steroids MDT patients pure neural (PNL). In addition to MDT, 24 (88% male aged 20-79 years, median=41) received a daily morning dose 60 mg prednisone (PDN) was gradually reduced by 10 during each following 5 months. PNL clinically diagnosed...
Background. Neuropathic pain (NP) is a very frequent and unrecognized condition in clinical practice. Therefore, it important to have reliable instrument assess subtypes various cultures. The Leeds Assessment of Symptoms Signs (LANSS) has been widely used validated many countries. Up now, there no reliability study this Brazil.
Aseptic meningitis is a common viral infection associated with human enteroviruses. The aim of the present study was to identify and characterize enteroviruses outbreaks sporadic cases aseptic that occurred in different regions Brazil between 2013 2017. Cerebrospinal fluids obtained from patients admitted public health facilities were analyzed. A total 303 positive for Human Enteroviruses (EV) by cell culture isolation median rate throughout year 12%. We able enterovirus serotypes 295...
Abstract Disability in leprosy is a direct consequence of damage to the peripheral nervous system which usually worse patients with no skin manifestations, an underdiagnosed subtype known as primary neural leprosy. We evaluated clinical, neurophysiological and laboratory findings 164 definite probable diagnoses. To better understand disease progression improve clinical recognition we compared characteristics short (≤12 months) long (>12 duration. Positive negative symptoms mediated by...
There are increasing reports of cases Guillain-Barré syndrome (GBS), as an adverse event immune checkpoint inhibitor (ICI) but postmarket data on the incidence this remains scarce. This study sought to conduct a comprehensive review GBS events arising secondary outcome ICI treatments in real-world patients, using Food and Drug Administration Adverse Event Reporting System (FAERS).