A5010070433- Multiple Sclerosis Research Studies
- Healthcare during COVID-19 Pandemic
- SARS-CoV-2 and COVID-19 Research
- Peripheral Neuropathies and Disorders
- T-cell and Retrovirus Studies
- Women's cancer prevention and management
- Systemic Sclerosis and Related Diseases
- Prenatal Screening and Diagnostics
- Mosquito-borne diseases and control
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Retinal and Optic Conditions
- COVID-19 and Mental Health
- Facial Nerve Paralysis Treatment and Research
- Assisted Reproductive Technology and Twin Pregnancy
- Polyomavirus and related diseases
- Nursing care and research
- Sarcoidosis and Beryllium Toxicity Research
- Research on Leishmaniasis Studies
- COVID-19 and healthcare impacts
- Healthcare Regulation
- Transcranial Magnetic Stimulation Studies
- Liver Diseases and Immunity
- Long-Term Effects of COVID-19
- Viral Infections and Vectors
Centre de Recherche en Économie et Management
2024
Fundação de Apoio à Pesquisa do Estado da Paraíba
2021-2023
Centro Universitário de João Pessoa
2019-2023
Universidade Estadual de Campinas (UNICAMP)
2021
Faculdade de Medicina do ABC
2019
Universidade Federal do Amazonas
2015
Universidade Federal da Paraíba
2015
ABSTRACT The expanding therapeutic arsenal in multiple sclerosis (MS) has allowed for more effective and personalized treatment, but the choice management of disease-modifying therapies (DMTs) is becoming increasingly complex. In this context, experts from Brazilian Committee on Treatment Research Multiple Sclerosis Neuroimmunology Scientific Department Academy Neurology have convened to establish Consensus MS, based their understanding that neurologists should be able prescribe MS DMTs...
We report on nine patients (eight cases of MS and one case NMOSD) who presented a disease relapse in close temporal association with their first AZD1222 vaccination dose against COVID-19. These had been stable for median period six years, no evidence activity change medication. After 13 days (7 to 25 days) from vaccination, they developed new increased disability lesions magnetic resonance imaging. Although this may be rare, it might an adverse event AZD1222.
<h3>Background and Objectives</h3> To describe the clinical features disease outcomes of coronavirus 2019 (COVID-19) in patients with neuromyelitis optica spectrum disorder (NMOSD). <h3>Methods</h3> The Neuroimmunology Brazilian Study Group has set up report severe acute respiratory syndrome (SARS-CoV2) cases NMOSD (pwNMOSD) using a designed web-based case form. All neuroimmunology outpatient centers individual neurologists were invited to register their across country. Data collected...
Little information is available regarding the incidence and clinical outcome of SARS-CoV2 infection in patients with multiple sclerosis (pwMS).To determine incidence, outcome, impact COVID-19 on pwMS.This observational study was prospectively performed a cohort pwMS (N = 11,560) followed up by 47 out 51 Brazilian MS referral centers that registered at REDONE platform from 13 March to 4 June 2020.The for 27.7/10,000 general population 29.2/10,000 inhabitants. A total 94 (77 women) patients,...
Prevalence rates of multiple sclerosis (MS) suggest an interrelationship between genetic and environmental factors, ranging worldwide.Objectives Clinical epidemiological characterization MS patients in João Pessoa, Paraíba city.Methods Study involving treated five services the city.Results It included 87 with MS, representing a prevalence 12.0 cases/100,000 population, mainly women (77%) white people (66.7%) mean age 43 years average first outbreak 32.2 years. Motor symptoms (65.5%)...
Abstract Acute Disseminated Encephalomyelitis (ADEM) is a demyelinating immune‐mediated disease characterized by bilateral and confluent lesions in white matter (WM), with an acute onset. This condition may arise due to myriad of etiological factors, encompassing mainly vaccines viral infections. case report describes 39‐y‐old patient who presented sudden onset fever, confusion, reduced level consciousness, associated paraparesis the lower limbs urinary retention, 2 d before admission...
O estudo possui como objetivo identificar as intervenções que alteram o desfecho da fase aguda do AVC. A presente pesquisa trata-se de uma revisão integrativa literatura. Para tal estudo, foi construída a seguinte pergunta norteadora: “Quais AVC.?”. Na elaboração norteadora e na busca evidências científicas utilizou-se estratégia PICO, significado: P paciente ou população; I intervenção indicador; C comparação controle outcome significa clínico, resposta resultado sendo se espera encontrar...
A Multiple Sclerosis Functional Composite Measure (MSFC) é escala para avaliação dos pacientes portadores de esclerose múltipla, desenvolvida pela National Society EUA em 1994, que envolve uma composição três testes - 9-Hole Peg Test, Timed 25-Foot Walk e PASAT abrangendo maneira multidimensional as principais funções neurológicas comprometidas nestes pacientes. MSFC foi aplicada 91 indivíduos sadios com o objetivo padronizá-la na população brasileira posterior uso nos diversos centros...
The Scientific Department of Neuroimmunology the Brazilian Academy Neurology (DCNI/ABN) and Committee for Treatment Research in Multiple Sclerosis Neuroimmunological Diseases (BCTRIMS) provide recommendations this document vaccination population with demyelinating diseases central nervous system (CNS) against infections general severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. We emphasize seriousness current situation view spread COVID-19 our country....
Introdução. O Distúrbio do Espectro da Neuromielite Óptica (DENMO) é uma doença autoimune rara que afeta o Sistema Nervoso Central, causando desmielinização. Pacientes com DENMO soropositivos frequentemente sofrem de dor e apresentam altas taxas depressão suicídio. Objetivo. revisar sistematicamente, na literatura, artigos científicos abordem as características uso medicamentos ação analgésica em pessoas DENMO. Método. A busca filtrou dos últimos 5 anos nas bases dados Embase, Scopus,...
Since 1993 the Federal Drug Administration approved use of immunomodulatory therapy in multiple sclerosis (MS), modifying natural course disease, as demonstrate our experience treatment MS patients at Treatment Center (CATEM).To evaluate patient behavior using for a period five years treatment.We selected 390 CATEM with relapsing-remitting (RRMS) and secondary progressive (SPMS) relapses.At initial 292 (61.5%) presented RRMS, 98 (20.6%) SPMS relapses, 27 (5.6%) 58 (12.1%) primary (PPMS). In...
Abstract Objective To describe the obstetric outcomes of patients with multiple sclerosis (MS) and impact pregnancy postpartum period on progression disease. Methods A case series study performed between December 2019 February 2020, reporting pregnancies occurred 1996 2019. The subjects included were women MS undergoing follow-up at an referral center in Northeastern Brazil, who had least one after onset symptoms, or their first relapse year delivery. Results In total, 26 38 analyzed – 32...
Introduction: Multiple sclerosis (MS) is a chronic and demyelinating disease of the central nervous system. Among symptoms that patients with MS may develop, depression stands out, which associated an important decline in quality life. The presence this symptom worse prognosis. There much support literature positive role non-pharmacological measures play controlling MS, range options for patient to choose from. Objectives: To analyze studies deal therapeutic strategies against MS. Methods:...
Introduction: Multiple sclerosis (MS) is a chronic disease that manifests through neuronal inflammation and demyelination. Patients exhibit symptoms can reduce their physical mental well-being, including worsened sleep quality. Objectives: To verify if there relationship between the level of Expanded Disability Status Scale (EDSS) quality in patients with MS. Methods: This an observational, field documentary study crosssectional, descriptive, quantitative approach. Sociodemographic...
Introduction: Tumor necrosis factor (TNF) antagonists have emerged as one of the most effective treatment options for patients with autoimmune diseases, including psoriatic arthritis. However, these agents carry a risk severe adverse effects, demyelinating disorders. The aim to report case multiple sclerosis associated use adalimumab. This is study. information this work was obtained through review medical record. Case report: A 40-year-old female arthritis on adalimumab (ADM) treatment. She...
Introduction: Arboviruses, such as Dengue (DENV), Zika (ZIKV), and Chikungunya (CHIKV), are infectious diseases that have become a public health challenge in Brazil. These viruses transmitted by mosquitoes can cause range of symptoms, from mild flu-like illness to severe sometimes fatal neurological syndromes. Objectives: To analyze the prevalence neurologic syndromes related arboviroses state Paraíba. Methods: This is cross-sectional, documentary, descriptive, quantitative observational...