A5011411754- Receptor Mechanisms and Signaling
- Neuroendocrine regulation and behavior
- Long-Term Effects of COVID-19
- Congenital heart defects research
- Neurotransmitter Receptor Influence on Behavior
- Multiple Sclerosis Research Studies
- Autism Spectrum Disorder Research
- Neuroscience and Neuropharmacology Research
- Anesthesia and Neurotoxicity Research
- Bone and Joint Diseases
- Neural dynamics and brain function
- Axon Guidance and Neuronal Signaling
- Olfactory and Sensory Function Studies
- SARS-CoV-2 and COVID-19 Research
- Acute Myeloid Leukemia Research
- Neonatal Respiratory Health Research
- COVID-19 and healthcare impacts
- Birth, Development, and Health
- Neurogenesis and neuroplasticity mechanisms
- Memory and Neural Mechanisms
- COVID-19 and Mental Health
- Polyomavirus and related diseases
- Obsessive-Compulsive Spectrum Disorders
- Retinoids in leukemia and cellular processes
- Hypothalamic control of reproductive hormones
Allen Institute
2023
Allen Institute for Neural Dynamics
2023
Universidade Estadual de Campinas (UNICAMP)
2021
Hospital Geral de Fortaleza
2020
Columbia University
2018
Champalimaud Foundation
2017
University of Maryland, Baltimore
2008-2012
Instituto Gulbenkian de Ciência
2010
Institute of Neurobiology
2006
Universidade Federal do Ceará
2004
Many neuropsychiatric diseases are associated with cognitive rigidity linked to prefrontal dysfunction. For example, schizophrenia and Parkinson's disease performance deficits on the Wisconsin Card Sorting Test, which evaluates attentional set shifting. Although genetic underpinnings of these disorders can be reproduced in mice, there few models for testing functional consequences. Here, we demonstrate that an analog developed marmosets recently adapted rats, is a behavioral model function...
Male sexual behavior is innate and rewarding. Despite its centrality to reproduction, a molecularly specified neural circuit governing male reward remains be characterized. We have discovered developmentally wired necessary sufficient for mating. This connects chemosensory input BNSTprTac1 neurons, which innervate POATacr1 neurons that project centers regulating motor output reward. Epistasis studies demonstrate are upstream of BNSTprTac1-released substance P following mate recognition...
<h3>Background and Objectives</h3> To describe the clinical features disease outcomes of coronavirus 2019 (COVID-19) in patients with neuromyelitis optica spectrum disorder (NMOSD). <h3>Methods</h3> The Neuroimmunology Brazilian Study Group has set up report severe acute respiratory syndrome (SARS-CoV2) cases NMOSD (pwNMOSD) using a designed web-based case form. All neuroimmunology outpatient centers individual neurologists were invited to register their across country. Data collected...
Little information is available regarding the incidence and clinical outcome of SARS-CoV2 infection in patients with multiple sclerosis (pwMS).To determine incidence, outcome, impact COVID-19 on pwMS.This observational study was prospectively performed a cohort pwMS (N = 11,560) followed up by 47 out 51 Brazilian MS referral centers that registered at REDONE platform from 13 March to 4 June 2020.The for 27.7/10,000 general population 29.2/10,000 inhabitants. A total 94 (77 women) patients,...
Hippocampal interneurons arise in the ventral forebrain and migrate dorsally response to cues, including hepatocyte growth factor/scatter factor which signals via its receptor MET. Examination of hippocampus adult mice MET had been inactivated embryonic proliferative zones showed an increase parvalbumin-expressing cells dentate gyrus, but a loss these CA3 region. An overall calretinin-expressing was seen throughout hippocampus. A similar deficit parvalbumin calretinin observed when...
Abstract Cholinergic interneurons (CINs) are believed to form synchronous cell assemblies that modulate the striatal microcircuitry and possibly orchestrate local dopamine release. We expressed GCaMP6s, a genetically encoded calcium indicator (GECIs), selectively in CINs, used microendoscopes visualize putative CIN dorsal striatum of freely moving mice. The GECI fluorescence signal from was composed signals individual somata were engulfed by widespread fluorescent neuropil. Bouts activation...
As angeítes isoladas do sistema nervoso central (SNC) são vasculites de pequenos e grandes vasos etiologia indeterminada que acometem exclusivamente a vasculatura nervoso. Geralmente não estão associadas doenças pré-existentes. Relatamos caso angeíte isolada SNC em um paciente com diagnóstico hematológico síndrome mielodisplásica.