A5079239524- Autoimmune Neurological Disorders and Treatments
- Multiple Sclerosis Research Studies
- Neurological and metabolic disorders
- Long-Term Effects of COVID-19
- Glycogen Storage Diseases and Myoclonus
- Genetics and Neurodevelopmental Disorders
- Peripheral Neuropathies and Disorders
- Genetic Neurodegenerative Diseases
- Acute Ischemic Stroke Management
- Neurological disorders and treatments
- Cerebral Venous Sinus Thrombosis
- Neurology and Historical Studies
- COVID-19 and healthcare impacts
- T-cell and Retrovirus Studies
- Polyomavirus and related diseases
- Ocular Diseases and Behçet’s Syndrome
- Infectious Encephalopathies and Encephalitis
- Protein Tyrosine Phosphatases
- Spatial Neglect and Hemispheric Dysfunction
- Chemotherapy-induced organ toxicity mitigation
- Diabetes Treatment and Management
- Extracellular vesicles in disease
- Migraine and Headache Studies
- Tuberous Sclerosis Complex Research
- Biochemical Acid Research Studies
Hospital de Clínicas Universidade Federal do Paraná
2023-2025
Instituto de Neurologia de Curitiba
2023-2025
Hospital Israelita Albert Einstein
2024-2025
Gdańsk Medical University
2024
Mayo Clinic in Florida
2024
Mayo Clinic
2024
Hospital de Clínicas
2023
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2019-2022
Universidade Estadual de Campinas (UNICAMP)
2021
Pontifícia Universidade Católica do Paraná
2012-2014
Currently, the Friedewald formula (FF) is main method for evaluating low-density lipoprotein cholesterol (LDL-c). Recently, many limitations have emerged regarding its use, including patients with triglyceride levels ≥400 mg/dL, diabetes mellitus, and kidney or hepatic chronic diseases. We analyzed use of FF in metabolic syndrome. selected known syndrome that fulfilled National Cholesterol Education Program Expert Panel on Detection, Evaluation Treatment High Blood Adults (Adult III) Final...
<h3>Background and Objectives</h3> To describe the clinical features disease outcomes of coronavirus 2019 (COVID-19) in patients with neuromyelitis optica spectrum disorder (NMOSD). <h3>Methods</h3> The Neuroimmunology Brazilian Study Group has set up report severe acute respiratory syndrome (SARS-CoV2) cases NMOSD (pwNMOSD) using a designed web-based case form. All neuroimmunology outpatient centers individual neurologists were invited to register their across country. Data collected...
Little information is available regarding the incidence and clinical outcome of SARS-CoV2 infection in patients with multiple sclerosis (pwMS).To determine incidence, outcome, impact COVID-19 on pwMS.This observational study was prospectively performed a cohort pwMS (N = 11,560) followed up by 47 out 51 Brazilian MS referral centers that registered at REDONE platform from 13 March to 4 June 2020.The for 27.7/10,000 general population 29.2/10,000 inhabitants. A total 94 (77 women) patients,...
To highlight the worldwide presence of
Abstract Background Autoimmune encephalitis (AIE) is a group of inflammatory diseases characterized by the presence antibodies against neuronal and glial antigens, leading to subacute psychiatric symptoms, memory complaints, movement disorders. The patients are predominantly young, delays in treatment associated with worse prognosis. Objective With support Brazilian Academy Neurology (Academia Brasileira de Neurologia, ABN) Society Child (Sociedade Neurologia Infantil, SBNI), consensus on...
A 42-year-old woman with a history of metastatic osteosarcoma and chronic kidney disease presented to our emergency department due acute altered mental status that had started two days after chemotherapy infusion ifosfamide etoposide. Initially, she was alert, confused, disoriented. On the third day, developed echolalia, perseveration, paroxysmal events behavioral arrest. brain magnetic resonance imaging (MRI) scan laboratory work up were unremarkable. An electroencephalogram (EEG) revealed...
ABSTRACT Background: The novel coronavirus disease 2019 (COVID-19) pandemic poses a potential threat to patients with autoimmune disorders, including multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). Such are usually treated immunomodulatory or immunosuppressive agents, which may tamper the organism’s normal response infections. Currently, no consensus has been reached on how manage MS NMOSD during pandemic. Objective: To discuss strategies those patients. Methods:...
Abstract Background Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are the most common autoimmune diseases of central nervous system (CNS). They present chronic relapsing courses that demand treatment with disease-modifying drugs (DMDs) to prevent inflammatory activity. Disease-modifying lead immunomodulation or immunosuppression through diverse mechanisms (e.g., shifting lymphocyte cytokine profile, suppressing specific subpopulations). Thus, patients more prone...
A 30-year-old woman developed a new-onset orbital pain and vertical binocular diplopia in the right upgaze within 3 days. An examination revealed normal primary gaze position left hypotropia ([Figure 1]), unreversed with forced duction. The pupils eye excycloduction were normal. magnetic resonance imaging (MRI) scan superior oblique muscle (SOM) tenosynovitis 2]). No infectious, autoimmune, metabolic or rheumatological etiologies identified, we concluded it was case of idiopathic Brown...
The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment a common feature this condition, it seldom emerges as the primary symptom. In study, we discuss case refractory dementia spectrum disorder. Interestingly, showed favorable outcome following autologous hematopoietic stem cell transplantation. We also provide an in-depth review current literature on use therapeutic approach for treatment disease.
Modelo do estudo: estudo transversal de base populacional realizado em ambulatórios e unidades saúde Curitiba - Paraná Brasil. Objetivo: evidenciar quais são os principais fatores risco cardiovascular da síndrome metabólica(SM) associados à esteatose hepática (EH. Metodologia: 75 pacientes com SM, sob tratamento ou não, após preencher critérios inclusão exclusão pesquisa, foram submetidos ultrassonografia para investigar a presença EH.Em seguida, foi avaliada relação entre EH...
A 59-year-old woman was admitted with acute left hemichorea-hemiballism. Blood glucose level 87 mg/dL. Head CT scan showed old infarcts (figure). The patient underwent thrombolysis IV alteplase (0.9 mg/kg) within 86 minutes of symptom onset, evolving partial improvement after 2 hours (video) and complete resolution 24 without other treatments. Brain MRI an stroke in the right insula (figure), known to be functionally connected posterolateral putamen.1 Hemichorea-hemiballism is uncommon...
A 55-year-old woman presented with facial and cervical chorea for 3 months (video). She had a previous history of traumatic right nerve palsy but no comorbidities or current medication use. Brain magnetic resonance imaging (MRI) was performed ([Figure 1]). Cerebrospinal fluid analysis unremarkable. Serum tests were positive human immunodeficiency virus (HIV) type 1 1.877.056 viral copies T-CD4 lymphocyte count 35/mm3. Darunavir, ritonavir, dolutegravir, lamivudine initiated. After 4 months,...