Bruna Klein da Costa

ORCID: 0000-0002-4752-2717
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About
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Research Areas
  • Multiple Sclerosis Research Studies
  • Peripheral Neuropathies and Disorders
  • Autoimmune Neurological Disorders and Treatments
  • Infectious Encephalopathies and Encephalitis
  • Genetics and Neurodevelopmental Disorders
  • Cytomegalovirus and herpesvirus research
  • Herpesvirus Infections and Treatments
  • Viral Infections and Immunology Research
  • Mosquito-borne diseases and control
  • Polyomavirus and related diseases
  • Brain Tumor Detection and Classification
  • Immunodeficiency and Autoimmune Disorders
  • Long-Term Effects of COVID-19
  • Acute Lymphoblastic Leukemia research
  • Advanced Neuroimaging Techniques and Applications
  • Kawasaki Disease and Coronary Complications
  • Otitis Media and Relapsing Polychondritis
  • Neurogenesis and neuroplasticity mechanisms
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Monoclonal and Polyclonal Antibodies Research
  • Systemic Lupus Erythematosus Research
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • RNA Interference and Gene Delivery
  • Fungal Plant Pathogen Control

Pontifícia Universidade Católica do Rio Grande do Sul
2016-2024

Instituto do Cérebro
2017-2021

University of Pennsylvania
2020

Grupo Santa Casa de Belo Horizonte
2020

Hospital São Lucas da PUCRS
2019

Zero to Three
2017

<h3>Objective</h3> The impetus for this consensus discussion was to recommend clinical trial designs that can deliver high-quality data effective therapies pediatric patients, in a reasonable timeframe, with key focus on short- and long-term safety. <h3>Methods</h3> International Pediatric Multiple Sclerosis Study Group convened meeting of experts review the advances understanding pediatric-onset multiple sclerosis (MS) advent trials population. <h3>Results</h3> In last few years, convincing...

10.1212/wnl.0000000000007572 article EN cc-by Neurology 2019-05-02

Abstract Background Autoimmune encephalitis (AIE) is a group of inflammatory diseases characterized by the presence antibodies against neuronal and glial antigens, leading to subacute psychiatric symptoms, memory complaints, movement disorders. The patients are predominantly young, delays in treatment associated with worse prognosis. Objective With support Brazilian Academy Neurology (Academia Brasileira de Neurologia, ABN) Society Child (Sociedade Neurologia Infantil, SBNI), consensus on...

10.1055/s-0044-1788586 article EN cc-by Arquivos de Neuro-Psiquiatria 2024-07-01

ABSTRACT Autoantibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been reported in patients with inflammatory central nervous system disorders including isolated optic neuritis (ON). We compared our MOG-IgG ON multiple sclerosis (MS) presenting ON. Methods and results: Among the total of 38 neuropathies, six were positive eight fulfilled diagnostic criteria for MS. All MS negative using a cell-based assay. When group, older (mean 47 years), more frequently male (ratio 2:1)...

10.1590/0004-282x20170121 article EN cc-by-nc Arquivos de Neuro-Psiquiatria 2017-10-01

A 20-year-old, previously-healthy woman presented with progressive tetraparesis, multiple cranial nerve involvement and pseudobulbar affect over three weeks.Brain MRI revealed a unique edematous brainstem lesion peripheral gadolinium enhancement (Figure 1).She was treated long-term antibiotics (21 days of ampicillin sulfamethoxazole/trimethoprim) high-dose intravenous corticosteroids.Oral prednisone slowly tapered full clinical recovery resolution the after five months 2).Idiopathic...

10.1590/0004-282x20170133 article EN cc-by-nc Arquivos de Neuro-Psiquiatria 2017-10-01
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