- Neurological Disorders and Treatments
- Multiple Sclerosis Research Studies
- Acute Ischemic Stroke Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Polyomavirus and related diseases
- Cerebrovascular and Carotid Artery Diseases
- Neurological Disease Mechanisms and Treatments
- Cerebrospinal fluid and hydrocephalus
- Human Health and Disease
- Biochemical effects in animals
- Herpesvirus Infections and Treatments
- Mycobacterium research and diagnosis
- Rheumatoid Arthritis Research and Therapies
- Chronic Lymphocytic Leukemia Research
- Cerebrovascular and genetic disorders
- Neurosurgical Procedures and Complications
- Sphingolipid Metabolism and Signaling
- Reproductive System and Pregnancy
- Toxin Mechanisms and Immunotoxins
- Botulinum Toxin and Related Neurological Disorders
- Healthcare Systems and Public Health
- Fungal Plant Pathogen Control
- Free Radicals and Antioxidants
National Pirogov Memorial Medical University, Vinnytsya
2013-2023
Thales (Portugal)
2020-2021
University of Basel
2013
Brain morphometry is widely used to diagnose and predict mainly neurodegenerative diseases, but cerebrovascular diseases have received much less attention, especially for predicting long-term consequences of stroke. The aim the research was investigate associations between changes in brain morphometric parameters stroke outcome at 90 days. 294 consecutive patients with acute were recruited. All participants underwent magnetic resonance imaging and/or computed tomography assessment as well...
Multiple sclerosis (MS) is a neurological disorder characterised by inflammatory demyelination and neurodegeneration in the central nervous system (CNS). Until recently, disease modifying treatment was based on agents requiring parenteral delivery, thus limiting long-term compliance. Basic treatments such as beta-interferon provide only moderate efficacy, although therapies for second-line highly active MS are more effective, they associated with potentially severe side effects. Fingolimod...
Реестр качества лечения инсульта (REgistry of Stroke Care Quality, RES-Q) позволяет оценить качество оказания помощи больным с инсультом в стационарах и сравнить ее качеством других странах. Цель исследования. Оценить стационарной мозговым Украине. Материалы методы. С 2017 года реестр RES-Q внесена информация по 14 305 пациентам из 90 больниц Украины. Средний возраст больных составил 68 лет. 85,08 % были ишемическим инсультом, 10,53 — внутримозговыми геморрагиями, 1,98 субарахноидальным...
The question of prospects using the data variability arterial pressure as a base predictor development, course and consequences brain stroke is considered on studied literature.Methods research: E-data Medline PubMed was used for thorough searching literature questions.Results. results scientific analysis testify to connection between hypertrophy left ventricle, endothelial dysfunction, development new cases auricles fibrillation. According AP day monitoring, direct positive mass index...
Annotation. The aim of the research is to investigate associations between white matter disease (WMD) parameters and index stroke lesion characteristics in patients with acute stroke. There are a number studies that have examined effect WMD on consequences cerebral stroke, but few them addressed issues its focus parameters. study establish relationships 294 consecutive were enrolled. All participants underwent magnetic resonance imaging (MRI) computed tomography (CT). Assessment for markers...
Ischemic stroke remains a pressing problem today. Its pathogenesis consists of sequential cascade reactions in the brain, which, addition to ischemia, are responsible for further damage brain tissue and slow down development compensatory regenerative mechanisms. Attempts break pathological have been going on decades. The first promising molecule that demonstrated potential scavenger (cleaner, absorber) excessive aggressive peroxides preclinical studies was MCI-186, which is used clinical...
Пропонується для ознайомлення та дискусії локальний протокол надання допомоги хворим з мозковим інсультом ТІА, створений на основі чинних нормативних документів (клінічних настанов, уніфікованих клінічних протоколів) в умовах спеціалізованого медичного закладу третинного рівня — Вінницької обласної психоневрологічної лікарні ім. акад. О.І. Ющенка. Локальний клінічний (маршрут пацієнта) враховує особливості організації медичної певному регіоні, матеріальне технічне оснащення, рівень...
Every year, the number of new cases strokes is increasing all over world. More than 62% are ischemic strokes. Ischemic stroke a serious medical and social problem one main causes death disability in Ukraine around The use drugs, task which to increase safety nervous tissue, has great importance pharmacotherapy stroke.
 aim study was analyze results cost-effectiveness calculations impact on budget during drug Xavron® for treatment patients with acute Ukraine.
 Research materials:...
Objective. To assess the association of enlarged perivascular spaces (EPVS) with cerebral small vessel disease (CSVD), some basic metabolic tests, brain atrophy and clinical outcome after territorial stroke.Methods. 90 patients acute stroke (<24 hours onset) were recruited. Modified Rankin scale Bartel index where used to outcome. Cerebral MRI was performed white matter lesions (WML), lacunes, EPVS in basal ganglia cortical-subcortical area a validated four-point visual rating scale....
Актуальность. Проведение сравнительного анализа репрезентативных региональных данных по уровню диагностики на госпитальном этапе ведения инсульта за определенный период времени и между различными лечебными учреждениями позволяет корректно сформировать комплекс лечебно-профилактических мероприятий разработать последовательные рекомендации их улучшению. Цель исследования: оценить динамику показателей качества клинико-аппаратной 2017–2019 гг. провести сравнительный анализ исследуемыми...
In this paper, we reviewed scientific sources on multiple sclerosis, analyzed the latest data peculiarities of cognitive dysfunction and comorbid pain syndrome in patients with sclerosis. Multiple sclerosis belongs to group chronic progressive demyelinating diseases a predominant lesion central nervous system. It affects over 2.5 million people worldwide is considered as one most disabling neurological disorders. Symptoms range from physical ones including loss vision, spasticity, bladder...
Cerebral small vessel disease (CSVD) is a heterogeneous group of disorders which affect perforating vessels the brain. Clinically CSVD manifest with various constellations symptoms, like cognitive, functional, affective as well lacunar stroke or intracerebral hemorrhage. It responsible for 25 % all strokes and are second contributor to dementia after Alzheimer’s disease. The gold standard diagnostic neuroimaging. main key features white matter hyperintensity (WMH), lacunes, enlarged...