A5088898602- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Prostate Cancer Diagnosis and Treatment
- Molecular Biology Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Renal cell carcinoma treatment
- Ultrasound and Hyperthermia Applications
- Adrenal and Paraganglionic Tumors
- Fetal and Pediatric Neurological Disorders
- Pituitary Gland Disorders and Treatments
- Pleural and Pulmonary Diseases
- Cancer, Hypoxia, and Metabolism
- Pediatric Urology and Nephrology Studies
- Seventeenth-Century Political and Philosophical Thought
- Diagnosis and treatment of tuberculosis
- Pneumothorax, Barotrauma, Emphysema
- Political Theory and Influence
- Soft tissue tumors and treatment
- Gastric Cancer Management and Outcomes
- Pneumonia and Respiratory Infections
- Cell Image Analysis Techniques
- Pathogenesis and Treatment of Hiccups
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2022
Istituto Giannina Gaslini
2022
SDN Istituto di Ricerca Diagnostica e Nucleare
2019-2021
Inoue Hospital
2016-2017
Abstract Despite the key-role of Prostate Imaging and Reporting Data System (PI-RADS) in diagnosis characterization prostate cancer (PCa), this system remains to be affected by several limitations, primarily associated with interpretation equivocal PI-RADS 3 lesions debated role Dynamic Contrast Enhanced-Magnetic Resonance (DCE-MRI), which is only used upgrade peripheral category 4 if enhancement focal. We aimed at investigating usefulness radiomics for detection PCa (Gleason Score ≥ 6)...
Splenomegaly is a quite common clinical feature of Philadelphia (Ph) negative chronic myeloproliferative neoplasms (MPNs) and its presence may, in some cases, drives treatment decision. Most importantly, palpable splenomegaly minor criterion for both pre-fibrotic/early primary myelofibrosis (PMF) diagnosis, even if assessment by physical examination poorly reliable accurate. On the other hand, despite International Working Group-Myeloproliferative Neoplasms Research Treatment European...
The role of dynamic contrast-enhanced-MRI (DCE-MRI) for Prostate Imaging-Reporting and Data System (PI-RADS) scoring is a controversial topic. In this retrospective study, we aimed to measure the added value DCE-MRI in combination with T2-weighted (T2W) diffusion-weighted imaging (DWI) using PI-RADS v2.1, terms reproducibility diagnostic accuracy, detection prostate cancer (PCa) clinically significant PCa (CS-PCa, Gleason Score ≥ 7). 117 lesions 111 patients were identified as suspicion by...
Prostate cancer (PCa) is a disease affecting an increasing number of men worldwide. Several efforts have been made to identify imaging biomarkers non-invasively detect and characterize PCa, with substantial improvements thanks multiparametric Magnetic Resonance Imaging (mpMRI). In recent years, diffusion kurtosis (DKI) was proposed be directly related tissue physiological pathological characteristic, while the radiomic approach proven key method study phenotypes. Our aim compare standard...
Background Clinical markers of cognitive decline in Parkinson's disease (PD) encompass several mental non-motor symptoms such as hallucinations, apathy, anxiety, and depression. Furthermore, freezing gait (FOG) specific alterations have been associated with dysfunction PD. Finally, although low cerebrospinal fluid levels amyloid-β42 found to predict PD, hitherto PET imaging amyloid-β (Aβ) failed consistently demonstrate the association between Aβ plaques deposition mild impairment PD...
Radiomics is rapidly advancing in precision diagnostics and cancer treatment. However, there are several challenges that need to be addressed before translation clinical use. This study presents an ad-hoc weighted statistical framework explore radiomic biomarkers for a better characterization of the radiogenomic phenotypes breast cancer. Thirty-six female patients with were enrolled this study. Radiomic features extracted from MRI PET imaging techniques malignant healthy lesions each...
Abstract Diffusion tensor imaging (DTI) is particularly suitable for kidney studies due to tubules, collector ducts and blood vessels in the medulla that produce spatially restricted diffusion of water molecules, thus reflecting high grade anisotropy detectable by DTI. Kidney DTI still a challenging technique where off-resonance susceptibility artefacts subject motion can severely affect reproducibility results. The aim this study design reliable processing pipeline assessing different image...
Rhinoplasty and surgical reconstruction of cartilaginous structures still remain a great challenge today. This study aims to identify an imaging strategy in order merge the information from CT scans magnetic resonance (MRI) acquisitions build 3D printed model true patient’s anatomy, for better planning. Using MRI, can be obtained about cartilage which nose is composed. Ten rhinoplasty candidate patients underwent both low-dose protocol scan specific MRI characterization nasal structures....
Abstract We report a case of 55-year-old woman with left breast cosmetic augmentation performed 5 years earlier, showing at ultrasound small amount peri-implant effusion suspicious for an anaplastic large cell lymphoma localization. The final diagnosis was obtained by cytology using fluid (6 ml). Subsequently, hybrid 18F-FDG PET/MRI used pre-operative staging and follow-up. An appropriate management BIA-ALCL could be even in cases effusion, comprehensive approach clinical imaging evaluation,...
Abstract Objective The aim of this study was to evaluate the prognostic value combined positron emission tomography (PET)/magnetic resonance imaging (MRI) parameters provided by simultaneous 18F-fluorodeoxyglucose (FDG) PET/MRI in patients with locally advanced oropharyngeal and hypopharyngeal squamous cell carcinomas (OHSCC). Methods Forty-five OHSCC who underwent FDG before (chemo)radiotherapy were retrospectively enrolled. Peak standardized uptake (SULpeak), metabolic tumor volume (MTV)...
We report on a 4-month-old boy who experienced severe coronavirus 2019 (COVID-19) pneumonia with necrotizing following catheter-related bloodstream infection (CR-BSI) by methicillin-susceptible Staphylococcus aureus (MSSA). On January 24, 2021, the presented to emergency department 3 day history of high fever and cough. Since first days life, he had been monitored hematologists for occurrence cytopenia secondary postnatal cytomegalovirus infection. This was characterized...
Quantification of hepatic virtual iron content (VIC) by using Multidetector Dual Energy Computed Tomography (DECT) has been recently investigated since this technique could offer a good compromise between accuracy and non-invasiveness for liver quantification. The aim our study is to investigate differences in VIC at different DECT time points (namely baseline arterial, venous tardive phases), identifying the most reliable also exploring underlying temporal trend these values.Eleven patients...
Pheochromocytomas may show atypical imaging findings leading to diagnostic pitfalls. We correlated the results of magnetic resonance (MRI) with those radionuclide studies in patients pheochromocytomas. T2-weighted (-w), T1-w chemical-shift and dynamic contrast enhanced (DCE) MRI sequences were evaluated assess tumor structure. 131Iodine metaiodobenzylguanidine (MIBG) scintigraphy, 18fluoro (F) deoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) or FDG PET/MRI for...
Neuroimaging with Magnetic Resonance Imaging (MRI) is one of the most useful tools available to study human brain in vivo. Several techniques provide insights into brain's structure, function, and connectivity. The aim this showcase feasibility employing advanced neuroimaging within clinical routine a patient neurological disorder. An 83 years-old male right motor aphasia somatosensory impairment underwent MRI protocol 3D-T1, FLAIR, diffusion-weighted tensor imaging, resting state functional...
Gastrointestinal stromal tumors (GISTs) are rare cancers originating from the gastrointestinal tract's interstitial cells of Cajal. This study explores utility quantitative Magnetic Resonance Imaging (MRI), particularly volumetric lesion segmentation, in preoperative evaluation large-mass abdominal GISTs. MRI offers high-resolution imaging without ionizing radiation, which is crucial for oncology patients requiring repeated scans. Advanced semi-automatic segmentation techniques were employed...
Abstract Kidney structural abnormalities are common features of Bardet-Biedl syndrome (BBS) patients that lead to a progressive decline in renal function. Magnetic resonance diffusion tensor imaging (DTI) provides useful information on microstructures but it has not been applied these patients. This study investigated using DTI detect BBS with no overt dysfunction. Ten subjects estimated glomerular filtration rates over 60 ml/min/1.73m 2 and 14 individuals matched for age, gender, body mass...
Dixon-based methods for the detection of fatty liver have advantage being non-invasive, easy to perform and analyze, provide a whole-liver coverage during acquisition. The aim study was assess feasibility approach fat quantification in type 2 diabetes (T2D) patients who underwent two different isocaloric dietary treatments: diet rich monosaturated acids (MUFA) multifactorial diet. Thirty-nine T2D were randomly assigned MUFA (n = 21) 18). mean values proton density fraction (PDFF) over whole...
The lack of validation and standardization represents the main drawback for a clear role whole-body diffusion weighted imaging (WB-DWI) prediction assessment treatment response in Hodgkin’s lymphoma (HL). We explored reliability an automatic approach based on WB-DWI technique to patients with HL. study included 20 HL patients, who had positron emission tomography (PET)/ magnetic resonance Imaging (MRI) performed before, during after chemotherapy. Using syngo.via MR Total Tumor Load tool, we...
Le but de l’article est mettre en évidence l’importance la question felicitas dans réflexion éthique et politique Leibniz, selon une réciprocité entre dimension individuelle commune. Cette recherche leibnizienne se déroule termes dynamiques : félicité liée à un progrès perpétuel des formes politiques, le n’est jamais accompli fois pour toutes, si bien que inquiétude ne s’opposent pas. La respublica doit être interprétée partir cet enjeu conceptuel politique.