A5011049734- GABA and Rice Research
- Biomedical Research and Pathophysiology
- Surgical site infection prevention
- Wound Healing and Treatments
- Metabolomics and Mass Spectrometry Studies
- Microbial Metabolic Engineering and Bioproduction
- Autophagy in Disease and Therapy
- Erythrocyte Function and Pathophysiology
- Diabetic Foot Ulcer Assessment and Management
- Consumer Perception and Purchasing Behavior
Kyushu University
2021-2023
Tohoku University
2019
Obesity is a major risk factor for end-stage kidney disease. We previously found that lysosomal dysfunction and impaired autophagic flux contribute to lipotoxicity in obesity-related disease, both humans experimental animal models. However, the regulatory factors involved countering renal are largely unknown. Here, we palmitic acid strongly promoted dephosphorylation nuclear translocation of transcription EB (TFEB) by inhibiting mechanistic target rapamycin kinase complex 1 pathway Rag...
Interferon (IFN)-γ is mainly secreted by CD4+ T helper 1 (Th1), natural killer (NK) and NKT cells after skin injury. Although IFN-γ well known regarding its inhibitory effects on collagen synthesis fibroblasts in vitro, information limited role wound healing vivo. In the present study, we analyzed how defect of affects healing. Full-thickness wounds were created backs wild type (WT) C57BL/6 IFN-γ-deficient (KO) mice. We percent closure, breaking strength, accumulation leukocytes, expression...