- Ultrasound Imaging and Elastography
- Elasticity and Material Modeling
- Advanced MRI Techniques and Applications
- Ultrasonics and Acoustic Wave Propagation
- Neuroscience and Music Perception
- Electrical and Bioimpedance Tomography
- Radiomics and Machine Learning in Medical Imaging
- Ultrasound and Hyperthermia Applications
- Body Composition Measurement Techniques
- Neural dynamics and brain function
- Optical measurement and interference techniques
- Numerical methods in engineering
- ECG Monitoring and Analysis
- Seismic Imaging and Inversion Techniques
- Spectroscopy Techniques in Biomedical and Chemical Research
- AI in cancer detection
- Thermoregulation and physiological responses
- Medical Image Segmentation Techniques
- Plant and Biological Electrophysiology Studies
- Simulation Techniques and Applications
- Numerical methods in inverse problems
- Diverse Music Education Insights
- Blind Source Separation Techniques
- Atrial Fibrillation Management and Outcomes
- Muscle activation and electromyography studies
iRhythm (United States)
2019-2023
Charité - Universitätsmedizin Berlin
2016-2019
University of Edinburgh
1839-2016
Humboldt-Universität zu Berlin
2016
Freie Universität Berlin
2016
Edinburgh College
2014
Pentum Group (United States)
1839
University of Glasgow
1839
To develop a compact magnetic resonance elastography (MRE) protocol for abdomen and to investigate the effect of water uptake on tissue stiffness in liver, spleen, kidney, pancreas.Nine asymptomatic volunteers were investigated by MRE before after 1 liter uptake. Shear-wave excitation at four frequencies was transferred from anterior posterior directions using pressurized air drivers. Tomographic representations shear-wave speed produced analysis multifrequency wave numbers axial coronal...
Abstract Early identification of atrial fibrillation (AF) can reduce the risk stroke, heart failure, and other serious cardiovascular outcomes. However, paroxysmal AF may not be detected even after a two-week continuous monitoring period. We developed model to quantify near-term in period, based on AF-free ECG intervals up 24 h from 459,889 patch-based ambulatory single-lead (modified lead II) recordings 14 days. A deep learning was used integrate morphology data with demographic rhythm...
Viscoelastic properties of the brain reflect tissue architecture at multiple length scales. However, little is known about relation between vital functions, such as perfusion, and macroscopic mechanical cerebral tissue. In this study, arterial spin labelling paired with magnetic resonance elastography to investigate relationship stiffness blood flow (CBF) in vivo human brain. The viscoelastic modulus, | G*|, CBF were studied deep gray matter (DGM) 14 healthy male volunteers following...
Purpose To introduce in vivo multifrequency single‐shot magnetic resonance elastography for full‐FOV stiffness mapping of the mouse brain and to compare neural tissues with different white‐to‐gray matter ratios. Methods Viscous phantoms 10 C57BL‐6 mice were investigated by 7T small‐animal MRI using a spin‐echo planar imaging sequence motion‐encoding gradients positioned before refocusing pulse. Wave images acquired over minutes 6 mechanical vibration frequencies between 900 1400 Hz....
Purpose Phase amplitude is a source of signal in magnetic resonance elastography (MRE) experiments but its exploitation experimental design has been limited due to the challenges phase wrap. This study addressed this aspect MRE through new developments algorithms, heuristic strategy, and user interface. Methods A test dataset with systematic variation three parameters—nested wrap, gradient, noise level—was developed choose phase‐unwrapping algorithms analyze their performance. application,...
Purpose To improve the resolution of elasticity maps by adapting motion and distortion correction methods for phase-based magnetic resonance imaging (MRI) contrasts such as elastography (MRE), a technique measuring mechanical tissue properties in vivo. Materials Methods MRE data brain were acquired with echo-planar (EPI) at 3T (n = 14) 7T 18). Motion parameters estimated using magnitude images. The real imaginary part complex corrected separately recombined. width point-spread function (PSF)...
Skeletal muscle viscoelastic properties reflect microstructure and neuromuscular activation. Elastographic methods, including magnetic resonance elastography, have been used to characterize in terms of region interest (ROI) measurements. The present study extended this approach create thresholded pixel-by-pixel maps skeletal during rest knee extension eleven subjects. ROI measurements were taken for individual quadricep muscles the quadriceps as a whole, parameter map pixels statistically...
Abstract Determining the effect of ageing on thigh muscle stiffness using magnetic resonance elastography (MRE) and investigate whether fat fraction cross-sectional area (CSA) are related to stiffness. Six healthy older adults in their eighth ninth decade eight young men were recruited underwent a 3 T MRI protocol including MRE Dixon imaging. Muscle stiffness, CSA calculated ROIs corresponding four quadriceps muscles (i.e. vastus lateralis (VL), medialis (VM), intermedius (VI), rectus...
MRI phase contrast imaging methods that assemble slice-wise acquisitions into volumes can contain interslice discontinuities (IPDs) over the course of scan from sources, including unavoidable physiological activity. In magnetic resonance elastography (MRE), this alter wavelength and tissue stiffness estimates, invalidating analysis. We first model behavior as jitter along z-axis 3D complex-valued wave volumes. A two-step image processing pipeline is then proposed removes IPDs. First,...
Purpose To investigate the effect of warmup by application thermal agent Deep Heat (DH) on muscle mechanical properties using magnetic resonance elastography (MRE) at 3T before and after exercise‐induced damage (EIMD). Materials Methods Twenty male participants performed an individualized protocol designed to induce EIMD in quadriceps. DH was applied thigh 50% exercise. MRE, T 2 ‐weighted MRI, maximal voluntary contraction (MVC), creatine kinase (CK) concentration, soreness were measured...
Magnetic resonance elastography (MRE) is a powerful technique for noninvasive determination of the biomechanical properties tissue, with important applications in disease diagnosis. A typical experimental scenario to induce waves tissue by time-harmonic external mechanical oscillation and then measure tissue's displacement at fixed spatial positions eight times during complete time-period, extracting dominant frequency signal from discrete Fourier transform time. Accurate reconstruction...
OPINION article Front. Integr. Neurosci., 24 April 2013 Volume 7 - | https://doi.org/10.3389/fnint.2013.00029
The viscoelastic properties of muscle have been measured for more than a century to describe disease, damage, recovery and performance. Magnetic Resonance Elastography (MRE) (Muthupillai et al . Science 1995;5232:1854–7) measures parameters soft tissue in vivo New software developed by the Clinical Research Imaging Centre (CRIC), MRE-J (Barnhill Proc Image J Dev Conf, Oct 2012), enables creation maps skeletal through transverse plane with MRE. In present study, thigh stiffness were created...
Following middle cerebral artery strokes, left hemisphere lesions can lead to aphasia.Similarly, right they phonagnosia (voice recognition disorder).In this study we investigated if the processing of phonemes could be dissociated from voice gender.Twenty seven stroke patients were recruited: 10 with aphasia, 6 without aphasia and a unique case cross-aphasia.Participants had rate sound stimuli as being male or female (gender task) /pa/ /ta/ (phoneme task).Because consisted in morphed sounds...
Conductors use body movements to communicate their interpretations of musical works though performance directions regarding selected features.The aim this study was examine how the kinematic features conducting relate compositional elements such as rhythmic patterns, melodic peaks, dynamic changes, and also they conductors' own interpretational comments.Six conductors with experience between four 29 years were interviewed asked annotate a score (Eine Kleine Nachtmusik by W. A. Mozart, No....
OPINION article Front. Hum. Neurosci., 11 August 2014Sec. Cognitive Neuroscience Volume 8 - 2014 | https://doi.org/10.3389/fnhum.2014.00618
Chronic headaches are a well-documented complaint of shunted hydrocephalic patients. However, it is also one the signs shunt malfunction. Cranial compliance deficiency may be cause chronic in some chronically patients with functioning shunts (often slit or smaller than normal ventricles). This study aims to use novel, non-invasive imaging technique, Magnetic Resonance Elastography (MRE) investigate role brain viscoelasticity pediatric