Ai Jia

ORCID: 0000-0002-1836-6022
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About
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Research Areas
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Water Treatment and Disinfection
  • Effects and risks of endocrine disrupting chemicals
  • Enterobacteriaceae and Cronobacter Research
  • Analytical chemistry methods development
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Biosensors and Analytical Detection
  • Advanced oxidation water treatment
  • Reproductive biology and impacts on aquatic species
  • Marine Toxins and Detection Methods
  • Antibiotics Pharmacokinetics and Efficacy
  • Water Quality Monitoring and Analysis
  • Probiotics and Fermented Foods
  • Marine and coastal ecosystems
  • Toxic Organic Pollutants Impact
  • Urban Stormwater Management Solutions
  • Fecal contamination and water quality
  • Drug-Induced Hepatotoxicity and Protection
  • Gut microbiota and health
  • Antibiotic Resistance in Bacteria
  • Liver physiology and pathology
  • Environmental Toxicology and Ecotoxicology
  • Liver Disease Diagnosis and Treatment
  • Hormonal and reproductive studies
  • Pediatric health and respiratory diseases

Chang'an University
2024-2025

Northeast Agricultural University
2022-2023

First Affiliated Hospital of Xi'an Jiaotong University
2004-2023

Xi'an Jiaotong University
2004-2023

The Metropolitan Opera (United States)
2023

University of Arizona
2012-2022

Rogers (United States)
2013-2022

Jilin University
2021

Peking University
2008-2020

First Hospital of Xi'an
2004

Thousands of organic micropollutants and their transformation products occur in water. Although often present at low concentrations, individual compounds contribute to mixture effects. Cell-based bioassays that target health-relevant biological endpoints may therefore complement chemical analysis for water quality assessment. The objective this study was evaluate cell-based suitability benchmark assess efficacy treatment processes. selected cover relevant steps the toxicity pathways...

10.1021/es403899t article EN Environmental Science & Technology 2013-12-10

This study reveals key disinfection byproduct (DBP) toxicity drivers in drinking water across the United States. DBPs, which are ubiquitous water, form by reaction of disinfectants, organic matter, bromide, and iodide generally present at 100-1000× higher concentrations than other contaminants. DBPs linked to bladder cancer, miscarriage, birth defects human epidemiologic studies, but it is not known as responsible. We report most comprehensive investigation date, with measurements extracted...

10.1021/acs.est.1c07998 article EN Environmental Science & Technology 2021-12-15

To investigate the occurrence of antibiotics in urban rivers and their association with antibiotic-resistant Escherichia coli, 20 (fluoro)quinolone (FQs), 16 tetracycline (TCs) degradation products, 25 sulfonamides (SAs) some products were determined 45 river samples 13 discharged wastewater collected from Wenyu River its tributaries 4 composite effluent sewage treatment plants Beijing, China. Fifteen FQs, eight TCs, including four chemicals, sixteen SAs, acetylated detected water. The SAs...

10.1021/es503700j article EN Environmental Science & Technology 2014-11-26

Abstract The presence of antibiotics in the environment is great concern because their potential for resistance selection among pathogens. In present study we investigated occurrence 19 sulfonamides, five N ‐acetylated sulfonamide metabolites, and trimethoprim Liao River basin adjacent Liaodong Bay, China, as well 10 human/agricultural source samples. Within 35 river samples, 12 four acetylated were detected, with dominant being sulfamethoxazole (66.6 ng/L), ‐acetylsulfamethoxazole (63.1...

10.1002/etc.508 article EN Environmental Toxicology and Chemistry 2011-02-26

Numerous studies have identified the presence and bioactivity of glucocorticoid receptor (GR) active substances in water; however, identification activity-balance GR compounds remained elusive. This study determined occurrence attenuation closed balance by determining those responsible. The observed vitro activity ranged from 39 to 155 ng dexamethasone-equivalent/L (ng Dex-EQ/L) secondary effluents four wastewater treatment plants. Monochromatic ultraviolet light 80 mJ/cm2 disinfection dose...

10.1021/acs.est.5b04893 article EN Environmental Science & Technology 2016-02-03

With the exception of polycarbonate (PC) baby bottles, little attention has been paid to bisphenol A (BPA) intake from packaged water consumption (PC dispensers), especially during summer weather conditions. We determined magnitude and variability urinary BPA concentrations in 35 healthy individuals largely relying upon PC satisfy their potable needs. used liquid chromatography-tandem mass spectrometry measure concentrations. questionnaire was administered July/August a spot urine sample...

10.1021/es304038k article EN Environmental Science & Technology 2013-02-28

Nitrification and biofilm growth within distribution systems remain major issues for drinking water treatment plants utilizing chloramine disinfection. Many chloraminated periodically switch to chlorine disinfection several weeks mitigate these issues, known as "chlorine burns". The evaluation of byproduct (DBP) formation during burns beyond regulated DBPs is scarce. Here, we quantified an extensive suite 80 emerging, unregulated from 10 DBP classes in two U.S. burn chloramination...

10.1021/acs.est.2c02002 article EN Environmental Science & Technology 2022-05-31

Cylindrospermopsin (CYN) is a potent toxic alkaloid produced by number of cyanobacteria frequently found in lakes and reservoirs used as drinking water sources. We report for the first time detailed pathways degradation CYN treatment with ozone. This was accomplished use ultra-high-performance liquid chromatography (UHPLC)-quadrupole time-of-flight mass spectrometry (QTOF MS), which revealed that readily degraded ozone at least 36 transformation products. Structural similarities among major...

10.1021/acs.est.5b04540 article EN Environmental Science & Technology 2016-01-06

Ulcerative colitis (UC) is a chronic and recurrent inflammatory bowel disease, the intestinal barrier an important line of defense against disease. Herein, we investigated effect Lactobacillus gasseri JM1 at different doses (1 × 106, 1 107, 108 CFU/day) on mice explored possible mechanism. The results showed that L. alleviated DSS-induced in mice, with reductions disease activity index (DAI), histological scores myeloperoxidase as well alleviation colonic shortening. Furthermore, regulated...

10.3390/nu15010139 article EN Nutrients 2022-12-28

Objectives:The objective of this study is to explore the incidence, characteristics, risk factors, and prognosis liver injury in patients with COVID-19.Methods: We collected clinical data 384 cases COVID-19 retrospectively analyzed factors patients.In addition, we followed patient two months after discharge.Results: A total 23.7% had injury, higher serum AST (P < 0.001), ALT ALP = 0.004), GGT bilirubin 0.002), indirect 0.025) direct 0.001) than control group.The median were mildly...

10.7150/ijms.81214 article EN cc-by-nc International Journal of Medical Sciences 2023-01-01
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