- Hydrology and Watershed Management Studies
- Guidance and Control Systems
- Flood Risk Assessment and Management
- Adaptive Control of Nonlinear Systems
- Spacecraft Dynamics and Control
- Plasma Diagnostics and Applications
- Hydrological Forecasting Using AI
- Advanced Sensor and Energy Harvesting Materials
- Meningioma and schwannoma management
- Hydrology and Drought Analysis
- Robotic Path Planning Algorithms
- Glioma Diagnosis and Treatment
- Hydraulic flow and structures
- Pituitary Gland Disorders and Treatments
- Hydrology and Sediment Transport Processes
- Space Satellite Systems and Control
- Groundwater and Isotope Geochemistry
- Groundwater flow and contamination studies
- Advanced SAR Imaging Techniques
- Fractional Differential Equations Solutions
- Microwave Imaging and Scattering Analysis
- Sparse and Compressive Sensing Techniques
- Computational Fluid Dynamics and Aerodynamics
- Tactile and Sensory Interactions
- Magnetic confinement fusion research
Xidian University
2016-2025
Beijing Information Science & Technology University
2025
China Aerospace Science and Technology Corporation
2015-2024
Anhui Medical University
2023-2024
Hunan University of Science and Engineering
2024
Beihang University
2016-2024
National University of Defense Technology
2013-2023
First People's Hospital of Yunnan Province
2015-2023
Shenzhen University
2019-2023
Peng Cheng Laboratory
2021-2023
Cushing's disease, also known as adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (PAs) that cause excess cortisol production, accounts for up to 85% of corticotrophin-dependent syndrome cases. However, the genetic alterations in this disease are unclear. Here, we performed whole-exome sequencing DNA derived from 12 ACTH-secreting PAs and matched blood samples, which revealed three types somatic mutations a candidate gene, USP8 (encoding ubiquitin-specific protease 8),...
Abstract Parabacteroides distasonis ( P. ) plays an important role in human health, including diabetes, colorectal cancer and inflammatory bowel disease. Here, we show that is decreased patients with hepatic fibrosis, administration of to male mice improves thioacetamide (TAA)- methionine choline-deficient (MCD) diet-induced fibrosis. Administration also leads increased bile salt hydrolase (BSH) activity, inhibition intestinal farnesoid X receptor (FXR) signaling taurochenodeoxycholic acid...
Critical-size bone defects are an important problem in clinical practice, which usually occurs severe trauma, or tumor resection, and cannot heal completely autonomously. Implantation of grafts is often required to promote the regeneration critical-size defects. Metal ions play role human health, as they affect body's metabolism tissue function. Strontium (Sr2+) can osteogenesis angiogenesis. Herein, we prepared nano-hydroxyapatite (nHA)/chitosan (CS) composite microspheres with a uniform...
Abstract Flexible pressure sensors based on thermoplastic polyurethane (TPU) conductive polymer foam can be applied to health monitoring, motion detection, and electronic skin. For satisfying the demand of long‐term use in high‐pressure range, TPU requires improvements detection stability, repeatability. In this paper, a flexible reduced graphene oxide (rGO)/thermoplastic porous with ultra‐wide range high‐stability is proposed. First, an elastic matrix fabricated via freeze‐drying. Then,...
Critical-size bone defects are a common and intractable clinical problem that typically requires filling in with surgical implants to facilitate regeneration. Considering the limitations of autologous allogeneic applications, such as secondary damage or immunogenicity, injectable microhydrogels osteogenic angiogenic effects have received considerable attention. Herein, polydopamine (PDA)-functionalized strontium alginate/nanohydroxyapatite (Sr-Alg/nHA) composite loaded vascular endothelial...
This paper deals with the second-order dynamic sliding-mode control (SODSMC) problem for nonminimum phase underactuated hypersonic vehicles. First, vehicle attitude model is introduced. The normal form and nature are discussed. Thus, system divided into minimum subsystem via decomposition approach. Second, SODSMC scheme developed. conventional controller designed two subsystems. Besides, sliding manifold provided subsystem. Simulation results presented to demonstrate effectiveness robustness...
Celastrol, derived from the roots of Tripterygium Wilfordi, shows a striking effect on obesity. In present study, role celastrol in cholestasis was investigated using metabolomics and transcriptomics. Celastrol treatment significantly alleviated cholestatic liver injury mice induced by α-naphthyl isothiocyanate (ANIT) thioacetamide (TAA). found to activate sirtuin 1 (SIRT1), increase farnesoid X receptor (FXR) signaling inhibit nuclear factor-kappa B P53 signaling. The protective diminished...
This paper addresses a novel SAR imaging scheme based on 1-bit sampling assisted with single-frequency threshold. The approach is able to considerably reduce the quantization cost. However, when technique simplifies system by reducing word length of each sample only 1 bit, amplitude information echo lost and high-order harmonics are introduced, degrading quality. strategy threshold linearly maintain shifts spectra away from component caused intermodulation. Hence, quality using sampled data...
The fractional reaction-diffusion equations play an important role in dynamical systems. Indeed, it is time consuming to numerically solve differential diffusion equations. In this paper, we present a parallel algorithm for the Riesz space equation. algorithm, which implemented with MPI programming model, consists of three procedures: preprocessing, solver and postprocessing. involves matrix vector multiplication addition. As authors' knowledge, first experimental results show that as...
Abstract As one of the three payloads for Advanced Space-based Solar Observatory (ASO-S) mission, Lyman-alpha (Ly α ) Telescope (LST) is composed instruments: a Corona Imager (SCI), Ly Disk (SDI) and full-disk White-light (WST). When working in-orbit, LST will simultaneously perform high-resolution imaging observations all regions from solar disk to inner corona up 2.5 R ⊙ (R stands mean radius) with spatial resolution 4.8″ 1.2″ coronal observations, respectively, temporal 30 – 120 s 1...
Abstract Daily streamflow modeling is an important tool for water resources management and flood mitigation. This study compared the performance of Xinanjiang (XAJ) model random forests (RF) method in a daily simulation, proposed several hybrid models based on XAJ model, wavelet analysis, RF (including XAJ-RF WRF XAJ-WRF model). The methods were applied to Shiquan station, located Upper Han River basin China. Five measures (NSE, RMSE, PBIAS, MAE, R) adopted evaluate accuracy. Results showed...
Flexible pressure sensors have been widely studied due to their potential applications in wearable electronics. However, the poor sensitivity and narrow working range seriously hinder developments practical applications. This article reports a flexible sensor characterizing with modulus gradient multilayered microstructure. The has an ultrahigh of 29.69 kPa<sub>−1</sub> structure formed by low Ag/hydrogenated styrene-butadiene block copolymer (SEBS) electrode layer high graphene...
In recent decades, gallium nitride (GaN) high-electron-mobility transistor (HEMT) has become increasingly popular for microwave applications due to its wide bandgap and high saturated electron velocity. However, self-heating inhibits the improvement of electrical characteristics reduces device reliability. this study, a thermoelectric analysis based on embedded microfluidic cooling is performed. By embedding microchannel into silicon carbide (SiC) substrate, coolant can be introduced...