A5089930387- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Magnetism in coordination complexes
- Luminescence and Fluorescent Materials
- Molecular Sensors and Ion Detection
- Metal-Organic Frameworks: Synthesis and Applications
- Cholinesterase and Neurodegenerative Diseases
- Animal Virus Infections Studies
- Alzheimer's disease research and treatments
- Microbial infections and disease research
- Intracerebral and Subarachnoid Hemorrhage Research
- High Altitude and Hypoxia
- Eicosanoids and Hypertension Pharmacology
- Metal complexes synthesis and properties
- Virology and Viral Diseases
- Advanced biosensing and bioanalysis techniques
- Crystallography and molecular interactions
- Neurogenesis and neuroplasticity mechanisms
- Mycobacterium research and diagnosis
- Burn Injury Management and Outcomes
- Cardiac Arrest and Resuscitation
- Blood donation and transfusion practices
- Nanocluster Synthesis and Applications
- Lung Cancer Diagnosis and Treatment
- Blood transfusion and management
Sun Yat-sen University
2004-2023
Linyi People's Hospital
2012-2023
Xinxiang Central Hospital
2019
National Center for Clinical Laboratories
2017
Beijing Hospital
2017
South Central Minzu University
2016
Chongqing Medical University
2010
The University of Texas Medical Branch at Galveston
2000
Shriners Hospitals for Children - Erie
1992-1995
Philipps University of Marburg
1980
Discrete dinuclear and polymeric heterometallic copper(II)-lanthanide(III) complexes have been synthesized upon variation of pH characterized by X-ray diffraction analysis. Reactions the ligand Htza (tetrazole-1-acetic acid) with copper(II) lanthanide(III) salts gave [CuLn(tza)4(H2O)5Cl] at low 3.5 2D coordination polymers high-nuclearity [{Cu2(OH)2}2{Cu12Ln6(mu3-OH)24(Cl)(1/2)(NO3)(1/2)(tza)12(H2O)18}](NO3)(9).8H2O (Ln = Gd or Nd) a higher 6.6. The acidity reaction solution can cause...
The aim of the present study was to investigate effects cytomegalovirus (CMV) infection on prognosis inflammatory bowel disease (IBD). Various databases were searched using a combination keywords associated with CMV and IBD. Subsequent selection relevant studies in line strict inclusion exclusion criteria, meta‑analysis conducted Stata 12.0 software. A total 195 initially retrieved, including 28 Chinese 167 English. Following unsuitable studies, 7 cohort 374 IBD patients included...
Amyloid protein can damage nerve cells through a variety of biological mechanisms including oxidative stress, alterations in calcium homeostasis, and proapoptosis. Edaravone, potent free radical scavenger possessing antioxidant effects, has been proved neuroprotective effect stroke patients. The current study aimed to investigate the effects EDA an A β -induced rat model AD, by studying 1–40 voltage-gated channel currents hippocampal CA1 pyramidal neurons, learning memory behavioral tests,...
Delayed fluid resuscitation during burn shock is thought to compromise the integrity of gut mucosa and allow enteric bacteria cross luminal wall infect other sterile organ systems. Superoxide dismutase, a free-oxygen radical scavenger; leupeptin, protease inhibitor; verapamil, calcium channel blocker, were studied evaluate their efficacy in maintaining cellular thermally burned rats whose had been delayed. Fifty male weighting 280 320 gm given full-thickness scald covering 50% total body...
Fluorophores with aggregation-induced emission enhancement (AIEE) characteristics applied in bioimaging have attracted more and attention recent years. In this work, a series of flavanone compounds AIEE was developed to fluorescence imaging mitochondria zebrafish. The were readily prepared by the thermal dehydration chalcone that obtained reaction o-hydroxyacetophenone benzaldehyde. Two these showed significant performance experiments, including optical spectra, quantum yield (φF), lifetime,...
Neurotrophic tyrosine kinase type 1 (NTRK1) plays critical roles in proliferation, differentiation, and survival of cholinergic neurons; however, it remains unknown whether enhanced expression NTRK1 neural stem cells (NSCs) can promote their differentiation into mature neurons. In this study, a plasmid encoding the rat gene was constructed transfected C17.2 mouse (NSCs). overexpression confirmed by western blot. The NSCs overexpressing an empty vector were treated with or without 100 ng/mL...
The derivatives of hyperforin, namely hyperforin acetate (2), 17,18,22,23,27,28,32,33-octahydrohyperforin (3), and N,N-dicyclohexylamine salt (4), have been investigated for their antitumor properties. In-vitro studies demonstrated that 2 4 were active against HeLa (human cervical cancer), A375 malignant melanoma), HepG2 hepatocellular carcinoma), MCF-7 breast A549 nonsmall cell lung K562 chronic myeloid leukemia), K562/ADR adriamycin-resistant K562) lines with IC(50) values in the range...
Fluorophores with aggregation-induced emission enhancement (AIEE) properties have attracted more attention in recent years. In order to realise valuable applications, the different kinds of AIEE molecules are serious need further development. Therefore, a novel flavone-based system derived from restriction intramolecular rotation (RIR) was designed and synthesized this work. The results revealed that six compounds showed typical characteristics, fluorescence emissions purple, blue, cyan...
Abstract The new octadecanuclear Cu‐Ln complex, [Cu 12 Nd 6 (OH) 24 (betaine) 16 (NO 3 ) (H 2 O) 10 ](NO )[PF ] 14 ·5H O, was synthesized, which crystallizes in triclinic P 1¯ space group, a = 18.649(6)Å, b 20.363(7)Å, c 19.865(7)Å, α 116.61(2)°, β 91.99(2)°, γ 117.93(2)°, V 5666(3)Å . Its crystal structure features 15+ core of pseudocubic O h symmetry, with the six ions positioned at vertices regular octahedron and twelve Cu located midpoints octahedral edges. Cu‐Nd metal framework may be...
Abstract Introduction A national survey on critical values in hematology of China laboratories was conducted to determine the current practice and assess quality indicators so as obtain a improvement. Methods Laboratories participating were asked submit general information, value reporting, status timeliness reporting. Results total 862 submitted results. The majority participants have included white blood cell count, platelet hemoglobin, prothrombin time, activated partial thromboplastin...
Nestin is a neuroepithelial stem cell marker that expressed in some types of tumor cells. Recent reports suggest may be closely related to malignant proliferation and migration. Acute leukemia (AL) characterized by lack differentiation, which results uncontrolled the bone marrow accumulation immature The expression function AL unclear. We investigated immunohistochemical patterns 87 patients included 47 cases acute myeloid (AML) 40 lymphoblastic (ALL), 20 complete remission (CR) from AML or...
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Minimal residual disease monitoring presents a number of theoretical and practical challenges. Recently it has been possible to meet some these challenges by combining new advanced biotechnologies. To monitor the tumor cells requires complex cocktails molecular probes that collectively provide sensitivities detection on order one cell per million total cells. Ultra-high-speed, multi parameter flow cytometry is capable analyzing at rates in excess 100,000 cells/sec. Residual selection marker...
To investigate the association between DD, ID and II genotypes of ACE gene carotid stenosis, to construct a network ACE-related genes regulating stenosis. Meta-analysis was used study three stenosis susceptibility ACE; functional annotation conducted by GO analysis; that regulate mechanisms established. showed DD were associated with analysis main biological processes involved in include: process transforming angiotensinogen into mature angiotensin; angiotensin's mediation brain's response...
Nobiletin is a natural product with multiple physiological activities and the main ingredient of Pericarpium Citri Reticulatae. We successfully discovered that nobiletin exhibits aggregation induced emission enhancement (AIEE) properties it has significant advantages such as large Stokes shift, good stability excellent biocompatibility. The increase in methoxy groups endows greater fat-solubility, bioavailability transport rate than corresponding unmethoxylated flavones. Ulteriorly, cells...
In recent years, aggregation-induced emission enhancement (AIEE) molecules have shown great potential for applications in the fields of bio-detection, imaging, optoelectronic devices, and chemical sensing. Based on our previous studies, we investigated fluorescence properties six flavonoids confirmed that compounds 1-3 good through a series spectroscopic experiments. Compounds with AIEE addressed limitation imposed by aggregation-caused quenching (ACQ) classic organic dyes owing to their...
Reperfusion damage has been identified as an important factor in multiorgan failure after severe burn injury. We wondered if leupeptin, a protease inhibitor, superoxide dismutase (SOD), scavenger of free oxygen radicals, or verapamil, calcium antagonist, would protect the cellular energy metabolism when they were given with fluid resuscitation that was delayed 6 hours Fifty male rats weighing 280 to 300 gm received 50% third-degree scald burn. Ten these at 30 minutes and 1 1/2 injury, 40 7...
In the crystal structure of title compound, [Cu(NO3)2(C6H7NO)2], copper(II) ion resides at an inversion centre and it has a 4 + 2 elongated ocatahedral coordination environment. The equatorial positions are occupied by two OH groups N atoms from pair neutral 2-(hydroxymethyl)pyridine ligands, while axial weakly ligated nitrate O atoms. Adjacent mononuclear complexes further joined together O—H⋯O hydrogen bonds to form linear chain along axis.