A5033916347- Prenatal Screening and Diagnostics
- Pregnancy and preeclampsia studies
- Parvovirus B19 Infection Studies
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Birth, Development, and Health
- Trauma and Emergency Care Studies
- Fetal and Pediatric Neurological Disorders
- HIV/AIDS Research and Interventions
- Cancer Genomics and Diagnostics
- Global Maternal and Child Health
- Hemophilia Treatment and Research
- Ectopic Pregnancy Diagnosis and Management
- Healthcare Systems and Public Health
- HIV, TB, and STIs Epidemiology
- Cardiac Arrhythmias and Treatments
- Pregnancy-related medical research
- Platelet Disorders and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- HIV/AIDS Impact and Responses
- Bariatric Surgery and Outcomes
- Cardiovascular Issues in Pregnancy
- Congenital Anomalies and Fetal Surgery
- Healthcare innovation and challenges
- Renal and related cancers
University of Washington
2018-2024
Community Link
2024
Ruchill Hospital
1992
Edgware Community Hospital
1984
Uterine leiomyomas may affect the performance of cell-free DNA (cfDNA)–based noninvasive prenatal testing (NIPT). We conducted a retrospective cohort study pregnant individuals with and without undergoing first-trimester cfDNA-based NIPT. Characteristics NIPT in patients (n=122) were compared those (n=937). Mean fetal fraction was lower (10.0% vs 11.5%; P =.001); however, rate indeterminate results different only obesity (body mass index [BMI] than 30) (5.3% 1.5%; =0.03). Total cfDNA...
OBJECTIVE--To determine the prevalence of HIV among pregnant women, in particular those whose behaviour or that their partners put them at "low risk" infection. DESIGN--Voluntary named anonymous testing women during 21 months (November 1988 to July 1990). SUBJECTS AND SETTING--All who planned continue pregnancy and attended clinics serving antenatal populations Edinburgh Dundee. All admitted for termination gynaecology wards Dundee outlying rural areas. MAIN OUTCOME MEASURES--Period antibody...
Reasons for first trimester noninvasive prenatal screening (NIPS) test failure in obese women remain elusive. As dilution from maternal sources may be explanatory, we determined the relationship between obesity, fetal fraction (FF), and total cell-free DNA (cfDNA) using our NIPS platform.We assessed differences (≤14 weeks) FF, indeterminate rate, cfDNA (n = 518) normal-weight 237) after exclusion of confounders (anticoagulation, autoimmunity, aneuploidy) controlling covariates.Fetal was...
Objective Low fetal fraction (FF) on cell-free DNA (cfDNA)-based noninvasive prenatal screening (NIPS) is a common etiology for indeterminate results. As maternal Black race implicated as risk factor low FF and more results, we sought to evaluate this association. Study Design This was single-institution, retrospective cohort study of cfDNA-based NIPS performed between May 2017 2022 with complete clinical data abstraction. We compared FF, rates, total cfDNA concentration among self-reported...
Evaluate the association between current recommendations for active labor duration in nulliparous women undergoing induction and adverse perinatal outcomes.Retrospective cohort study from 2012 to 2015. Subjects were nulliparous, 18-44 years, cephalic, singleton ≥37 weeks who reached labor. We created three subgroups, defined by 6 10cm as < median, median-95th percentile, >95th percentile based on contemporary curves. evaluated subgroups cesarean delivery, chorioamnionitis, blood loss (EBL),...