Lauren K. Truby

ORCID: 0000-0002-1874-0205
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About
Contact & Profiles
Research Areas
  • Mechanical Circulatory Support Devices
  • Cardiac Structural Anomalies and Repair
  • Transplantation: Methods and Outcomes
  • Renal Transplantation Outcomes and Treatments
  • Cardiac Arrest and Resuscitation
  • Heart Failure Treatment and Management
  • Organ Transplantation Techniques and Outcomes
  • Cardiovascular Function and Risk Factors
  • Congenital Heart Disease Studies
  • Viral Infections and Immunology Research
  • Cardiac pacing and defibrillation studies
  • Fuel Cells and Related Materials
  • Metabolomics and Mass Spectrometry Studies
  • Cardiac Ischemia and Reperfusion
  • Cardiac Arrhythmias and Treatments
  • Mesenchymal stem cell research
  • Cardiac Fibrosis and Remodeling
  • Cardiac and Coronary Surgery Techniques
  • Metabolism and Genetic Disorders
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Issues in Pregnancy
  • Mitochondrial Function and Pathology
  • Cardiovascular and exercise physiology
  • Congenital heart defects research
  • Pulmonary Hypertension Research and Treatments

The University of Texas Southwestern Medical Center
2023-2025

Twitter (United States)
2025

Southwestern Medical Center
2023-2024

Texas Health Harris Methodist Hospital Fort Worth
2024

Duke University
2020-2023

Duke Medical Center
2019-2022

Columbia University Irving Medical Center
2012-2021

Duke University Hospital
2019-2021

Clinical Research Institute
2021

Columbia University
2014-2019

Left ventricular distention (LVD) during venoarterial extracorporeal membrane oxygenation (VA-ECMO) support is increasingly recognized but seldom reported in the literature. The current study defined LVD as not present (LVD−); subclinical (LVD+, evidence of pulmonary edema on chest radiograph AND artery diastolic blood pressure greater than 25 mm Hg within first 2 hours intensive care unit admission); or clinical (LVD++, need for decompression left ventricle immediately following VA-ECMO...

10.1097/mat.0000000000000553 article EN ASAIO Journal 2017-04-19

Mortality for refractory cardiogenic shock remains high. In this patient cohort, there have been mixed results in mechanical circulatory support device use as a bridge-to-decision therapy. We evaluated continuous-flow external ventricular assist (VAD), CentriMag VAD (Thoratec Corp., Pleasanton, CA), patients with various causes of shock.This is retrospective review adult who underwent surgical insertion From January 2007 through June 2012, 143 received VAD. The cause was failure medical...

10.1161/circheartfailure.113.000271 article EN Circulation Heart Failure 2014-07-16

Refractory cardiogenic shock (RCS) is associated with significant morbidity and mortality, current mainstays of medical therapy appear inadequate. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) represents an increasingly accepted for RCS. Demographics, past history, preoperative characteristics, outcomes, adverse events were collected consecutive patients who received VA-ECMO support RCS at our institution from March 2007 to December 2013. One hundred seventy-nine a mean age 56.9...

10.1097/mat.0000000000000225 article EN ASAIO Journal 2015-04-23

Combination of venoarterial extracorporeal membrane oxygenation (VA-ECMO) and a percutaneous microaxial left ventricular assist device (pLVAD), or "EC-VAD," has been reported in cases decompression with mixed results. We conducted retrospective review patients who received EC-VAD (n = 29) isolated VA-ECMO therapy (ECMO-only; n 196) for refractory cardiogenic shock between February 2011 October 2014. Fourteen then Impella pLVAD (E→EC-VAD), 15 the pump (I→EC-VAD). E→EC-VAD demonstrated...

10.1097/mat.0000000000000804 article EN ASAIO Journal 2018-05-07

Background: Bridge to transplantation (BTT) with left ventricular assist devices (LVADs) is a mainstay of therapy for heart failure in patients awaiting (HT). Criteria HT listing do not differ between medically managed and those mechanically bridged HT. The objectives the present study were evaluate impact BTT LVAD on posttransplantation survival, describe differences causes 1-year mortality patients, risk factors without at time Methods: Using United Network Organ Sharing database, we...

10.1161/circulationaha.118.036932 article EN Circulation 2019-06-17

Background: Continuous-flow left ventricular assist devices (CF-LVADs) have become a standard treatment choice in advanced heart failure patients. We hypothesized that practice patterns with regards to CF-LVAD utilization vary significantly among transplant centers and impact waitlist outcomes. Methods Results: The United Network for Organ Sharing registry was queried identify adult patients who were waitlisted transplantation (HT) between 2008 2015. Each patient assigned propensity score...

10.1161/circheartfailure.117.004586 article EN Circulation Heart Failure 2018-04-01

Background: Advanced heart failure therapies such as left ventricular assist device (LVAD) implantation require intricate follow-up and complex care. We sought to explore the burden of psychosocial risk factors among patients with LVAD their impact on postimplant outcomes using Interagency Registry for Mechanically Assisted Circulatory Support. Methods: Adult in Support requiring durable between 2008 2017 were included. Individuals determined have if they had one following: (1) limited...

10.1161/circheartfailure.120.006910 article EN Circulation Heart Failure 2020-09-01

Background: Palliative care improves quality of life in patients with heart failure. Whether men and women failure derive similar benefit from palliative interventions remains unknown. Methods: In a secondary analysis the PAL-HF trial (Palliative Care Heart Failure), we analyzed differences among assessed for differential effects intervention by sex. Differences clinical characteristics quality-of-life metrics were compared between at serial time points. The primary outcome was change Kansas...

10.1161/circheartfailure.119.006134 article EN Circulation Heart Failure 2020-04-01
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