- Polysaccharides and Plant Cell Walls
- Polysaccharides Composition and Applications
- Ginseng Biological Effects and Applications
- Microbial Metabolites in Food Biotechnology
- Fungal Biology and Applications
- Phytochemistry and Biological Activities
- Quinazolinone synthesis and applications
- Seaweed-derived Bioactive Compounds
- Glycosylation and Glycoproteins Research
- Galectins and Cancer Biology
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Biological and pharmacological studies of plants
- Natural product bioactivities and synthesis
- Immune cells in cancer
- Genetics, Aging, and Longevity in Model Organisms
- Enzyme Production and Characterization
- Phytochemicals and Antioxidant Activities
- Food Quality and Safety Studies
- Advanced Synthetic Organic Chemistry
- Gut microbiota and health
- Ubiquitin and proteasome pathways
- Mitochondrial Function and Pathology
- Asymmetric Hydrogenation and Catalysis
- Organophosphorus compounds synthesis
Northeast Normal University
2015-2025
Beijing Technology and Business University
2025
Beijing Normal University
2021
Tianjin University of Science and Technology
2018-2019
Ludong University
2007-2019
Boston University
2012-2019
Google (United States)
2018
Biopolymères Interactions Assemblages
2018
Kanion Pharmaceutical (China)
2014-2016
Sichuan University
2013-2015
One advantage of the nematode Caenorhabditis elegans as a model organism is its suitability for in vivo optical microscopy. Imaging C. often requires animals to be immobilized avoid movement-related artifacts. Immobilization has been performed by application anesthetics or introducing physical constraints using glue specialized microfluidic devices. Here we present method immobilizing polystyrene nanoparticles and agarose pads. Our technique technically simple, does not expose worm toxic...
Human gut Bacteroides and Parabacteroides species play crucial roles in human health are known for their capacity to utilize diverse polysaccharides. Understanding how these bacteria medicinal polysaccharides is foundational developing polysaccharides-based prebiotics drugs. Here, we systematically mapped the utilization profiles of 20 different by 28 species. The growth exhibited substantial variation across bacterial Ginseng promoted multiple species; contrast, Dendrobium selectively...
Inflammation is a component of tumour progression mechanisms. Neutrophils are common inflammatory infiltrate in many tumours, but their regulation and functions neoplasia not understood. We recently demonstrated that pro-inflammatory IL-17-producing cells recruited blood neutrophils into the peritumoural stroma hepatocellular carcinoma by epithelium-derived CXC chemokines. Here we show substantial population accumulates hepatocellular, cervical, colorectal, gastric carcinomas, this...
Laser severing of individual axons in the nematode Caenorhabditis elegans revealed that apoptotic executioner caspase CED-3 and its regulator CED-4/Apaf-1 play an unexpected beneficial role promoting axonal regeneration.
The current optogenetic toolkit lacks a robust single-component Ca2+-selective ion channel tailored for remote control of Ca2+ signaling in mammals. Existing tools are either derived from engineered channelrhodopsin variants without strict selectivity or based on the stromal interaction molecule 1 (STIM1) that might crosstalk with other targets. Here, we describe design light-operated (designated LOCa) by inserting plant-derived photosensory module into intracellular loop an ORAI1 channel....
GPS serves as an effective protective barrier against ethanol-induced gastric ulcers in rats mainly through the excellent suppression of oxidative stress and inflammation.
The esterification of galacturonic acid with methanol and/or acetic is important for the structural analysis pectin. Although several methods have been reported determining degree methylesterification (DM) and acetylation (DAc), present study compares optimizes three (titration, FT-IR HPLC) using commercial citrus pectin (CP). Our results showed that DM CP was 47.0%, 47.6% 48.0% as determined by titration, HPLC, respectively, suggesting determination nearly identical any these methods....
Pectins are a class of acidic polysaccharides with complex structures. Different pectin molecules composed different domains, which have an important impact on their biological activity.This study aimed to determine the structural features and antioxidant activities pectic isolated from Veronica peregrina L.The polysaccharide was L by water extraction fractionated ion exchange chromatography gel permeation chromatography. The structure were determined Fourier transforminfrared spectroscopy...