A5081471261- Acute Myocardial Infarction Research
- COVID-19 Clinical Research Studies
- Heart Failure Treatment and Management
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- COVID-19 and healthcare impacts
- Cardiac Imaging and Diagnostics
- Long-Term Effects of COVID-19
- Lipoproteins and Cardiovascular Health
- Sepsis Diagnosis and Treatment
- Renal function and acid-base balance
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Antiplatelet Therapy and Cardiovascular Diseases
- Mechanical Circulatory Support Devices
- Cardiovascular Conditions and Treatments
- Mobile Learning in Education
- Platelet Disorders and Treatments
- Hormonal Regulation and Hypertension
- Extracellular vesicles in disease
- Congenital Heart Disease Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Vitamin C and Antioxidants Research
Sigmund Freud University Vienna
2017-2024
Wilhelminen Hospital
2015-2023
Ludwig Boltzmann Institute for Digital Health and Prevention
2020-2023
Heinrich Heine University Düsseldorf
2021
Düsseldorf University Hospital
2021
Ludwig Boltzmann Institute for Cancer Research
2020
Medical University of Vienna
2010-2019
Ludwig Boltzmann Cluster for Cardiovascular Research
2019
University College London
2011
Ruijin Hospital
2011
Hypoxic hepatitis (HH) is the most frequent cause of acute liver injury in critically ill patients. No clinical data exist about new onset jaundice patients with HH. This study aimed to evaluate incidence and effect Two hundred six consecutive HH were screened for development during course Individuals preexisting or cirrhosis at time admission (n = 31) excluded from analysis. Jaundice was diagnosed plasma total bilirubin levels >3 mg/dL. One-year-survival, infections, cardiopulmonary,...
While contributors to system delay in ST-elevation myocardial infarction (STEMI) are well described, predictors of patient-related delays less clear. The aim this study was identify that cause delayed diagnosis STEMI a metropolitan care (VIENNA network) and investigate possible association with long-term mortality.The population investigated consisted 2366 patients treated for acute the Vienna registry from 2003-2009. Multivariable regression modelling performed (a) onset pain first medical...
Excess cardiovascular (CV) morbidity and mortality has been observed in patients with COVID-19. Both interleukin-32 (IL-32) interleukin-34 (IL-34) have hypothesized to contribute CV involvement COVID-19.This prospective, observational study of laboratory-confirmed COVID-19 infection was conducted from 6 June 22 December 2020 a tertiary care hospital Vienna, Austria. IL-32 IL-34 levels on admission were collected tested for their association disease short-term defined by the presence coronary...
The physiological response to high-level endurance exercise, such as running a marathon, poses several beneficial but also potentially harmful metabolic changes. objective of this study was determine the impact marathon (M) and ultra-marathon (UM) on inflammation iron homeostasis in paired samples. Fifteen well-trained, non-professional athletes (14 males, 1 female) performed both 130 km traditional 42.195 marathon. We determined markers before, immediately after, within 5 days after...
We evaluated the effects of nebivolol, a third generation beta-blocker capable increasing NO-bioavailability on portal pressure, and splachnic systemic haemodynamics in cirrhotic hypertensive rat model.Male Sprague-Dawley rats underwent sham operation (SO) or bile duct ligation (BDL). When cirrhosis was fully developed, animals were orally treated with low-dose (5 mg/kg) high-dose (10 nebivolol (NEBI) vehicle (VEH) for 7 days. Heart rate (HR), mean arterial pressure (MAP), (PP) superior...
The emergency medical service (EMS) provides rapid pre-hospital diagnosis and transportation in ST-elevation myocardial infarction (STEMI) systems of care. Aim the study was to assess temporal regional characteristics EMS-related delays a metropolitan STEMI network. Patient call-to-arrival EMS at site (call-to-site), time from hospital (site-to-door), call-to-door, patient’s location, month, weekday, hour activation were recorded 4751 patients referred tertiary center with suspicion STEMI....
The optimal duration of dual anti-platelet therapy (DAPT) following percutaneous coronary intervention (PCI) is still a matter debate. Biomarkers may help to identify patients who will benefit from extended DAPT. aim the study was test interaction between lipid parameters and platelet function in with artery disease (CAD) on DAPT.Overall, 58 DAPT were prospectively included PCI stable CAD. Platelet markers, i.e. mean volume (MPV), distribution width (PDW), fraction reticulated thrombocytes...
Circulating platelet micro-RNAs (miRNAs) may be used to monitor function during dual antiplatelet therapy (DAPT). Aim of the study was measure plasma levels specific miRNAs (miRNA-223, -150, -21 and -126) after physician-driven cessation chronic P2Y12 inhibition differences in expression these between different oral inhibitors clopidogrel, prasugrel ticagrelor, respectively.Patients with coronary artery disease (CAD) on DAPT maintenance dose (including aspirin 100 mg OD, plus clopidogrel 75...
(1) Background: Extracellular vesicles (EVs) have been recognized as a cellular communication tool with cardioprotective properties; however, it is unknown whether cardioprotection by remote ischemic conditioning (RIC) involves EVs. (2) Methods: We randomized patients ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) to additionally receive protocol of RIC or sham-intervention. Blood was taken before and immediately, 24 h, four days one...
Background: Coronavirus disease (COVID-19) was first described at the end of 2019 in China and has since spread across globe. Red cell distribution width (RDW) is a potent prognostic marker several medical conditions recently been suggested to be value COVID-19. Methods: This retrospective, observational study consecutive patients with COVID-19 conducted from March 12, 2020 December 4, Wilhelminenhospital, Vienna, Austria. RDWlevels on admission were collected tested for their predictive...