A5076124202- Lipoproteins and Cardiovascular Health
- Takotsubo Cardiomyopathy and Associated Phenomena
- Diabetes, Cardiovascular Risks, and Lipoproteins
- ECG Monitoring and Analysis
- Long-Term Effects of COVID-19
- Neurosurgical Procedures and Complications
- Cardiac Arrest and Resuscitation
- Cardiovascular Disease and Adiposity
- Pharmaceutical Economics and Policy
- Adipokines, Inflammation, and Metabolic Diseases
- Electroconvulsive Therapy Studies
- Dietary Effects on Health
- Artificial Intelligence in Healthcare
- Cancer, Lipids, and Metabolism
- Cardiac Health and Mental Health
- Antiplatelet Therapy and Cardiovascular Diseases
- COVID-19 Clinical Research Studies
- Atrial Fibrillation Management and Outcomes
- Non-Invasive Vital Sign Monitoring
- COVID-19 and healthcare impacts
- Cardiac tumors and thrombi
- Venous Thromboembolism Diagnosis and Management
- Lipid metabolism and disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Renal and Vascular Pathologies
Wilhelminen Hospital
2021-2025
Sigmund Freud University Vienna
2022-2024
Medical University of Vienna
2023
Cardiogenic shock (CS) is a severe complication of acute coronary syndrome (ACS) with mortality rates approaching 50%. The ability to identify high-risk patients prior the development CS may allow for pre-emptive measures prevent CS. objective was derive and externally validate simple, machine learning (ML)-based scoring system using variables readily available at first medical contact predict risk developing during hospitalization in ACS. Observational multicentre study on ACS hospitalized...
Recent advances in machine learning provide new possibilities to process and analyse observational patient data predict outcomes. In this paper, we introduce a processing pipeline for cardiogenic shock (CS) prediction from the MIMIC III database of intensive cardiac care unit patients with acute coronary syndrome. The ability identify high-risk could possibly allow taking pre-emptive measures thus prevent development CS. We mainly focus on techniques imputation missing by generating...
Acute coronary syndrome (ACS) remains a major challenge in clinical practice, requiring rapid and effective antithrombotic treatment to mitigate adverse ischemic events while minimizing the risk of bleeding. In recent years, results from several trials addressing this issue through various approaches have substantially improved landscape for patients presenting with ACS. The emergence new, potent P2Y12 inhibitors has significantly enhanced thrombotic reduction different strategies...
Excess cardiovascular (CV) morbidity and mortality has been observed in patients with COVID-19. Both interleukin-32 (IL-32) interleukin-34 (IL-34) have hypothesized to contribute CV involvement COVID-19.This prospective, observational study of laboratory-confirmed COVID-19 infection was conducted from 6 June 22 December 2020 a tertiary care hospital Vienna, Austria. IL-32 IL-34 levels on admission were collected tested for their association disease short-term defined by the presence coronary...
Abstract Background Participation in ultra-endurance races may lead to a transient decline cardiac function and increased cardiovascular biomarkers. This study aims assess alterations biventricular immediately five days after the competition relation elevation of high-sensitivity Troponin I (hs-cTnI) N-terminal-pro-brain-natriuretic-peptide (NT-proBNP). Methods Results Fifteen participants an ultramarathon (UM) with running distance 130 km were included. Transthoracic echocardiography...
Background: Takotsubo syndrome (TTS) is an important type of acute heart failure with significant risk complications and death. In this analysis we sought to identify predictors for in-hospital clinical outcome in TTS patients present long-term outcomes. Methods: from the Austrian national registry, univariable multivariable analyses were performed severe requiring immediate invasive treatment or leading irreversible damage, such as cardiogenic shock, intubation, stroke, arrhythmias...
It is suggested that the changes in atherosclerosis happen mainly under influence of non-fasting lipids. To date, studies postprandial state were primarily performed on healthy subjects. This exploratory, cross-sectional study investigates change lipid profile, inflammation, and platelet activation patients with different cardiovascular risk profiles state.The studied population consists 66 risks: a history chronic coronary syndrome (CCS) diabetes mellitus type 2 (DM2) (n = 20), CCS without...
Abstract Background Patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) face an increased risk of cardiac events, including arrhythmias. Current guidelines therefore recommend ECG monitoring for at least 24 hours after AMI in patients ST segment elevation (STEMI) and high-risk non-ST (NSTEMI). However, the last decades medical treatment has been substantially improved, limiting arrhythmias post-PCI. Furthermore, continuous puts additional...
To analyze the psychocardiological profile and clinical characteristics in acute phase of takotsubo syndrome (TTS).Prospective multicenter cohort study TTS patients evaluating as well prevalence somatic, depressive, panic, stress anxiety disorders. Assessment illness perception resilience syndrome.All 27 evaluated were female with a mean age 68 years (±11.4 years). The apical type was found 60% patients, followed by combined 30% patients. Main symptom leading to hospital admission chest pain...
In the real world only about 20 % of patients with ASCVD are at target range, as shown by SANTORINI trial (1). Therefore, there is still a great need for improvement lipid-lowering therapy (LLT). Our Lipid Registry was set up retrospective study including who visited our outpatients ward focusing on The indications were: low-density lipoprotein cholesterol (LDL-c) > 130 mg/dL in LLT- naive acute coronary syndrome (ACS), artery disease (CAD) not optimal LLT, familial hypercholesterolemia...
Background: Renal disease is common in patients with cardiovascular (CVD) and associated adverse outcomes. Cardiac magnetic resonance (CMR) advanced mapping techniques the gold standard for characterizing myocardial tissue, renal tissue often visualized on these maps. However, it remains unclear whether T1 times accurately reflect dysfunction or predict Aim: To analyze relationship between times, dysfunction, Adverse outcomes were defined as all-cause death. Methods: measured native...
Abstract Aims This study aims to investigate the prevalence of Takotsubo syndrome (TTS) as a percentage total number acute coronary (ACS), including non‐STE‐elevation myocardial infarction and ST‐elevation infarction, well short‐term outcome TTS patients before during COVID‐19 pandemic. Methods results We compared from two different periods: (i) Period 1 (before pandemic): March 30 December 2019, (ii) 2 (during 2020. The retrospective database was created archives participating hospitals or...
Abstract Funding Acknowledgements Type of funding sources: None. Introduction In general, most people spend their day in a non-fasting state. Hence, it is suggested that the changes atherosclerosis happen mainly under influence lipids. Up to date, studies postprandial state were primarily performed on healthy subjects. Aim This exploratory, cross-sectional study investigates change lipid profile, biomarkers inflammation, as well markers platelet activation patients with different...
Abstract Funding Acknowledgements Type of funding sources: Private company. Main source(s): Sanofi AVentis Reports about a pleiotropic potential pro-protein convertase subtilisin/kexin type 9 inhibitor are scarce. This hypothesis-generating study investigates the platelet reactivity after standardized oral fat tolerance testing (OFTT) under an optimized lipid-lowering therapy (statin plus ezetimibe) alone and during add-on treatment with alirocumab. We investigated ten patients chronic...
Reports about a pleiotropic potential of pro-protein convertase subtilisin/kexin type 9 inhibitor are scarce. This hypothesis-generating study investigates the platelet reactivity after standardized Oral Fat Tolerance Testing (OFTT) under an optimized lipid-lowering therapy (statin plus ezetimibe) alone and during add-on treatment with alirocumab. We investigated ten patients Chronic Coronary Syndrome (CCS). Lipid variables markers function were assessed fasting state 3 5 hours OFTT using...
Abstract Introduction Measuring lipid panel in the fasting state can be inconvenient for patients and may aggravate their compliance. Moreover, people spend most of day nonfasting state. Hence, it suggests that changes process atherosclerosis happen mainly under influence lipids. Up to date, studies postprandial were primarily performed healthy subjects. Aim This exploratory study investigates change profile platelet activity with different cardiovascular risk profiles Methods The studied...
Abstract Background There is an increasing amount of evidence suggesting multiple fatal complications in Takotsubo Syndrome. However, findings on the long-term outcome are scarce and show inconsistent evidence. Methods This a single-center study prognosis patients admitted from September 2006 to August 2019. We investigated clinical features, prognostic factors with syndrome. Furthermore, survivors non-survivors different cause death were compared. Results Overall, 147 included study. The...