A5059560258- Chronic Obstructive Pulmonary Disease (COPD) Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sarcoidosis and Beryllium Toxicity Research
- Pediatric health and respiratory diseases
- Respiratory and Cough-Related Research
- Asthma and respiratory diseases
- Pulmonary Hypertension Research and Treatments
- Respiratory Support and Mechanisms
- Inhalation and Respiratory Drug Delivery
- Healthcare Systems and Public Health
- Medical and Biological Ozone Research
- Hydrogen's biological and therapeutic effects
- Medical Imaging and Pathology Studies
- Systemic Sclerosis and Related Diseases
- Chemical Reactions and Isotopes
- Gastroesophageal reflux and treatments
- Vasculitis and related conditions
- Occupational and environmental lung diseases
- Child and Adolescent Health
- Long-Term Effects of COVID-19
- Neonatal Respiratory Health Research
- Mycobacterium research and diagnosis
- Cancer Diagnosis and Treatment
- Heparin-Induced Thrombocytopenia and Thrombosis
- Venous Thromboembolism Diagnosis and Management
Central Scientific Research Institute of Tuberculosis Russian Academy of Medical Sciences
2016-2025
Central Research Institute
2011-2024
Currently, chronic obstructive pulmonary disease (COPD) is a global health issue and one of the leading causes death in world. COPD therapy includes pharmacological non-pharmacological approaches that can significantly improve clinical symptoms reduce frequency exacerbations disease. Methodology . The target audience these recommendations are therapists, general practitioners, pulmonologists. Each thesis-recommendation about diagnostic therapeutic procedures was graded according to scales...
The guidelines have been developed by the Russian Respiratory Society (RRS) based on analysis of papers published during last 5 years in MEDLINE and ENBASE databases Cochrane library. results were subsequently reviewed independent experts with consideration opinion physicians general practitioners. A quality a strength evidence assessed using worldwide criteria. are focused epidemiology social burden chronic obstructive pulmonary disease (COPD), pathogenesis, clinical signs, characterization...
Treatment of patients with chronic obstructive pulmonary disease (COPD) is one the most important tasks clinical medicine due to high prevalence and mortality from COPD. COPD as a heterogeneous requires different approaches depending on severity course Clinical guidelines have become principal document that regulates aspects management patients. Algorithms decision making are crucial part because they help achieving balance between in situations simple graphics. The simplified approach for...
This article contains clinical guidelines and current approaches to diagnosis treatment of idiopathic pulmonary fibrosis (IPF). The aims development this were improve early detection efficacy pharmacological non-pharmacological therapy IPF. Achieving these goals indicates improvement in medical care quality for patients. These are intended pulmonologists, therapeutists other specialists, healthcare managers providers
Hypersensitivity pneumonitis (HP) is an inflammatory and/or fibrotic lung disease that occurs in response to repeated inhalation of broad-spectrum aerosol antigens. The prevalence HP ranges from 0.3 0.9 cases per 100,000 population. basis treatment therapy includes glucocorticoids, immunosuppressants, and antifibrotic drugs. target audience these clinical recommendations are general practitioners, pulmonologists, pathologists, radiologists, medical rehabilitation specialists. Methods. Each...
Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic fibrotic interstitial pneumonia with progressive course and poor prognosis. The prevalence IPF in the Russian Federation about 8 – 12 cases per 100,000 population. basic treatment antifibrotic agents. Methodology . target audience these clinical recommendations are therapists, general practitioners, pulmonologists, pathologists, radiologists, medical rehabilitation doctors. Each thesis-recommendation diagnostic therapeutic...
Sarcoidosis is a multi-organ granulomatosis of unknown origin. Modern diagnostic methods allow detecting this disease at an early stage. The absence specific markers requires comprehensive approach to diagnosis based on comparison radiation, clinical, morphological and functional data. course sarcoidosis without damage the respiratory system presents significant difficulties. It extremely important understand time means starting Sarcoidosis’s treatment avoid initiation hormones cytostatics...
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Goal of the study: to investigate frequency mycobacteriosis in practice pulmonologists and phthisiologists. Materials methods. The analysis included medical files 156 patients with various non-specific respiratory diseases tuberculosis who were examined 2011-2014 non-tuberculous mycobacteria found their sputum. Results study. pulmonary was diagnosed 93 (59.6%) out corresponded criteria American Thoracic Society etiotropic treatment prescribed. While detection other considered as innidiation...
The main goals of COPD therapy are to achieve clinical stability with minimal manifestations and low risk relapse. proposed control concept by analogy asthma has not been quite well characterized yet. is defined as "the long - term maintenance a situation impact symptoms on the patient’s life absence exacerbations." in considered desirable potentially achievable for most patients COPD. Pharmacotherapeutic options constantly expanding. may be useful when decision treatment made dynamic...
Show the possibilities of diagnosing non - tuberculous mycobacteriosis lungs (NTML) in practice pulmonologist.A survey 90 patients with a confirmed diagnosis was presented. The pulmonary established accordance criteria proposed 2007 by American Thoracic Society and Infectious Diseases (ATS/IDRS). Among patients, 55 (61.1%) women prevailed, average age 51.2±15.3 years. Patients were evaluated complaints, presence concomitant diseases lungs, carried out computed tomography chest high...
Incidence and prevalence of non-tuberculous mycobacteriosis (NTM) are recorded in many countries, but the rates vary. There no official statistics on incidence NTMs Russian Federation at moment. The regulatory expert clinical database for has not yet been developed. aim thе article is to share experience Federal State Scientific Institution “Central Research Institute Tuberculosis” (FSSI “CRIT”) working with patients NTMB over past 7 years. Methods. study included 190 a confirmed diagnosis...
An impact of acute exacerbation COPD (AECOPD) on the course and prognosis chronic obstructive pulmonary disease depends severity exacerbation. Moderate severe exacerbations are considered as clinically significant events. Clinical studies investigating a role inhalational therapy for risk AECOPD differed significantly in important parameters patients involved were not fully described real clinical practice. Tiotropium alone did demonstrate any benefit over other therapies, such inhaled...
Summary. A multicenter (12 centers) retrospective analysis of health status 83 sarcoidosis patients in time diagnosis and after 10 years treatment has been performed. In diagnosis, 47 % the had complete remission pulmonary manifestations; mean forced spirometric values have not reduced (excluding initially treated with anti-TB drugs). Patients systemic steroids or during yrs were less likely to (36.5 %) more recurrent course (57.1 compared those steroids. Pentoxifylline administration...
Interstitial changes in the lungs could be caused by vast majority of diseases including tuberculosis, sarcoidosis, hypersensitive pneumonitis, metastatic injury lungs, etc. Differential diagnosis pulmonary dissemination remains an urgent and challenging clinical task. This article is a review published literature presentation case patient with interstitial lung disease. The demonstrates diagnostic difficulties identification cause injuries. was incidentally found this initially considered...
Idiopathic pulmonary fibrosis (IPF) is a severe lung disease, with death occurring within 2-5 years after its onset. IPF affects people in the second half of life. Its causes are unknown. Before 1999, was out from group idiopathic interstitial diseases as separate nosological entity. Practitioners very often (80%) make diagnostic errors and prescribe antibiotics, anti-inflammatory drugs, which worsen course this disease. The distinctive feature pathogenesis absence inflammation, clinically...
Goal of the study: to investigate structural and functional specific features macrophages cytokine profiles bronchoalveolar lavage in new relapsing respiratory sarcoidosis (RS). Materials methods. The study included comparative light optical electronic microscopic examinations macrophages, macrophage formula profile 120 patients suffering from different forms RS. It was found that case RS mostly M1 phenotype were detected lavage. They had high level IL-8, IL-2, IL-1β production...
Purpose of the study to role serum glycoproteins CA 19–9 and 125 as a potential non-invasive biomarker progressive fibrosis in interstitial lung diseases. Materials methods . The included 77 patients with Based on presence/absence signs progression over previous 6 months, were divided into 2 groups. All underwent forced spirometry, body plethysmography, diffusion test, computed tomography chest, concentrations 19-9 125. Results In group fibrotic phenotype diseases (ILD), higher levels...
Objective: to evaluate treatment effectiveness in patients with mycobacterial pulmonary disease and its association mycobacteria detection sputum. Materials methods. The study enrolled 196 confirmed disease. diagnosis was established as per ATS/IDSA criteria (2007). were divided into two groups: group 1 consisted of 108 nontuberculous (NTM) detected sputum; 2 60 NTM BAL and/or lung tissue samples. Female prevailed (78.6%). average patients’ age 56.9 ± 11.3 years. time period from diagnosing...