- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tuberculosis Research and Epidemiology
- Sarcoidosis and Beryllium Toxicity Research
- Mycobacterium research and diagnosis
- Inhalation and Respiratory Drug Delivery
- Esophageal and GI Pathology
- Airway Management and Intubation Techniques
- Diagnosis and treatment of tuberculosis
- Respiratory and Cough-Related Research
- Myasthenia Gravis and Thymoma
- Esophageal Cancer Research and Treatment
- Infectious Diseases and Tuberculosis
- Salivary Gland Tumors Diagnosis and Treatment
- Foreign Body Medical Cases
- Radiomics and Machine Learning in Medical Imaging
- Pleural and Pulmonary Diseases
- Antifungal resistance and susceptibility
- Chromatography in Natural Products
- Systemic Sclerosis and Related Diseases
- Microwave-Assisted Synthesis and Applications
- Appendicitis Diagnosis and Management
- Autoimmune and Inflammatory Disorders
Central Research Institute
2016-2024
Central Scientific Research Institute of Tuberculosis Russian Academy of Medical Sciences
2014-2024
Burdenko Neurosurgery Institute
2015
Objective: to evaluate effectiveness of the complex treatment patients with pulmonary tuberculosis (PTB) and concomitant tracheobronchial TB (TBTB) using pathogenetic therapy. Materials methods. The study enrolled 60 divided into two groups. main group included 30 PTB TBTB, who received containing both chemotherapy therapy (corticosteroids, inhalations lymphotropic therapy). comparison similar diseases (a retrospective analysis), only chemotherapy. Results. demonstrated more rapid cessation...
The guidelines describe modern approaches to equipping and ensuring endoscopic examinations of the digestive respiratory systems in accordance with objectives improving their quality, safety efficiency. focus is on diagnostics precancerous diseases early cancer gastrointestinal tract bronchi. Based analysis evidence-based medicine data, conditions for from minimum necessary expert level are provided, including integrating digital solutions into protocols reports, creating databases...
Sarcoidosis is a multi-organ granulomatosis of unknown origin. Modern diagnostic methods allow detecting this disease at an early stage. The absence specific markers requires comprehensive approach to diagnosis based on comparison radiation, clinical, morphological and functional data. course sarcoidosis without damage the respiratory system presents significant difficulties. It extremely important understand time means starting Sarcoidosis’s treatment avoid initiation hormones cytostatics...
Tuberculosis (TB) is currently the leading cause of death among bacterial infectious diseases. The spectrum disease manifestations depends on both host immune responses and ability Mycobacterium tuberculosis to resist it. Small non-coding RNAs are known regulate gene expression; however, their functional role in relationship M. with poorly understood. Here, we investigated effect small sRNAs MTS1338 MTS0997 properties by creating knockout strains. We also assessed survival wild type mutant...
The ability of high-definition (HD) videobronchoscopy to detect airway involvement in sarcoidosis has not been evaluated previously.What is the role HD identification sarcoidosis-associated abnormalities (AAs)? What are patterns AAs more commonly observed and frequently associated with detection granulomas endobronchial biopsy (EBB)?In this prospective international multicenter cohort study, consecutive patients suspected underwent inspection an videobronchoscope EBB using a standardized...
Objective. To evaluate endosonographic images (EGI) for different peripheral lung lesions (PPLs) genesis, to identify patterns of malignancy in the differential diagnosis tuberculosis (TB), mycobacteriosis (NTM), neoplasm, compare main combinations variants echo characteristics visualized during rEBUS navigation with data a comprehensive microbiological, cytological and morphological studies. Methods. A cohort retrospective study included 145 patients (81 women (mean age 44.94±0.24 years) 64...
To evaluate the efficacy and safety of tranbronchial cryobiopsy
This clinical case shows the experience in concurrently using video-assisted bronchoscopy and endosonography a patient with mediastinal adenopathy for differential diagnosis between tuberculous metastatic changes. It demonstrates possibilities limitations of both classical transesophageal EUS-b-FNA echobronchoscope.
In December 2018 the patient over 60 years old sought medical help with complaints of persistent cough. Based on computed tomography data there were identified sings (symptoms) right lung lower lobe atelectasis. To run this diagnostics performed 6 bronchoscopies narrowed down by bronchi checks up only and described central cancer picture. At same time biopsy taken during one appeared non informative. Fine needle mediastinal lymph nodes bronchial wall was twice: at Tomsk Cancer Research...
In the Russian Federation, there is an increase in patients with pulmonary tuberculosis combination comorbid pathologies, including Crohn's disease. There also a tendency to of and non-tuberculosis mycobacteriosis, which makes it difficult select adequate therapy reduces effectiveness treatment. Bronchial one complications process often masks onset this connection, diagnosis bronchi difficult. A young patient history disease was diagnosed bronchial mycobacteriosis. Upon admission, presence...
<h3></h3> Дифференциальная диагностика инфильтратов легочной ткани представляет трудности, обусловленные отсутствием специфических признаков клинических и радиологических проявлений. В дифференциально-диагностическом ряду легочных преимущественно рассматривают триаду нозологических форм: пневмония, туберкулез, рак. Диагностика туберкулезного инфильтрата основана на микробиологическом исследовании мокроты респираторных образцов, получаемых при бронхоскопии — бронхосмыва бронхоальвеолярного...
Data regarding the efficacy of virtual bronchoscopy (VB) compared to radial endobronchial ultrasound (rEBUS) for minimally invasive diagnostics peripheral pulmonary lesions (PPLs) are still controversial. Aim. To assess comparative VB versus plus rEBUS in patients with PPLs. Methods. The study enrolled 36 subjects PPLs detected by chest high resolution computed tomography (HRCT). All had various biopsy methods (based on navigation) alone or combination each other, followed cytological,...
<b>Background:</b> A choice of approach for endosonography and needle biopsy in sarcoidosis patients is still a debatable question, data different studies are conflicting. <b>Aim:</b> To compare efficacy EBUS-TBNA vs EUS-b-FNA unselected cohort. <b>Mehods:</b> Dataset from national Registry Endobronchial Ultrsound (REBUS) with confrimed cases was extracted. Direct comparison made between acceses to mediastinal lymphatic nodes. <b>Results:</b> 91 (41 males) confirmed were extracted, mean age...