A5024612590- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Cancer, Lipids, and Metabolism
- Urinary and Genital Oncology Studies
- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Cancer Immunotherapy and Biomarkers
- Health Systems, Economic Evaluations, Quality of Life
- Genital Health and Disease
- Economic and Financial Impacts of Cancer
- Healthcare Policy and Management
- Inflammatory Bowel Disease
- Radiopharmaceutical Chemistry and Applications
- Urological Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Immunotherapy and Immune Responses
- Microscopic Colitis
- Hormonal and reproductive studies
- Statistical Methods in Clinical Trials
- Poverty, Education, and Child Welfare
- Multiple and Secondary Primary Cancers
- Inflammatory Biomarkers in Disease Prognosis
- Renal cell carcinoma treatment
- Colorectal Cancer Surgical Treatments
Cedars-Sinai Medical Center
2025
University of California, Los Angeles
2023-2024
Precision Research (United States)
2024
John Wiley & Sons (United States)
2023
UCLA Health
2023
Northwestern University
2016-2022
Rutgers, The State University of New Jersey
2010-2022
Rutgers New Jersey Medical School
2022
University of Michigan–Ann Arbor
2020
Northwestern Medicine
2019
The dark side of melanin exposed Sun worshippers may have more to worry about than the DNA damage that occurs while they're relaxing on beach. It seems photoproducts responsible for cancer-causing mutations in skin cells continue be generated hours after sunlight exposure. Premi et al. find a key mediator this delayed is melanin, pigment thought protect against cancer (see Perspective by Taylor). They propose “chemiexcitation” model which reactive oxygen and nitrogen species induced...
Abstract Purpose: The heterogeneity of androgen receptor (AR)-activity (AR-A) is well-characterized in heavily treated metastatic castration-resistant prostate cancer (mCRPC). However, the diversity and clinical implications AR-A treatment-naïve primary largely unknown. We sought to characterize localized understand its molecular implications. Experimental Design: Genome-wide expression profiles from prostatectomy or biopsy samples 19,470 patients were used, all with independent pathology...
Abstract Black men die more often of prostate cancer yet, interestingly, may derive greater survival benefits from immune-based treatment with sipuleucel-T. Since no signatures immune-responsiveness exist for cancer, we explored race-based immune-profiles to identify vulnerabilities. Here show in multiple independent cohorts comprised over 1,300 patient samples annotated either self-identified race or genetic ancestry, tumors African ancestry have increases plasma cell infiltrate and...
No AccessJournal of UrologyAdult Urology1 Jan 2015National Trends in the Management Low and Intermediate Risk Prostate Cancer United States Adam B. Weiner, Sanjay G. Patel, Ruth Etzioni, Scott E. Eggener WeinerAdam Weiner Pritzker School Medicine, University Chicago, Illinois , PatelSanjay Patel Section Urology, EtzioniRuth Etzioni Division Public Health Sciences, Fred Hutchinson Research Center, Seattle, Washington EggenerScott Department Surgery, View All Author...
BACKGROUND More than 3.6 million men in the United States harbor a diagnosis of prostate cancer (PCa). The authors sought to provide in‐depth analyses causes death for contemporary survivors. METHODS performed population‐based cohort study (2000‐2016) assess diagnosed with PCa stratified by demographics and tumor stage. Using general population data, they calculated standardized mortality ratios (SMRs) as observed‐to‐expected ratios. RESULTS In total, 752,092 PCa, including 200,302 who died...
No AccessJournal of UrologyAdult Urology1 Feb 2016Bladder Cancer Mortality in the United States: A Geographic and Temporal Analysis Socioeconomic Environmental Factors Norm D. Smith, Sandip M. Prasad, Amit R. Patel, Adam B. Weiner, Joseph J. Pariser, Aria Razmaria, Chieko Maene, Todd Schuble, Brandon Pierce, Gary Steinberg SmithNorm Smith Section Urology, University Chicago Pritzker School Medicine, Chicago, Illinois , PrasadSandip Prasad Department Medical South Carolina, Charleston,...
This study is a comprehensive, longitudinal assessment of the characteristics special care patients. Demented patients in units (SCUs) within four nursing homes were compared with their demented counterparts same facilities who not placed SCUs. Results this preliminary suggest that two groups differ level cognitive impairment, behavior, and functional physical status. No deleterious or beneficial effects associated SCU residence during 6-month period.
Abstract Inflammatory bowel disease (IBD) is an established risk factor for colorectal cancer. Recent reports suggesting IBD also a prostate cancer (PC) require further investigation. We studied 218 084 men in the population‐based UK Biobank cohort, aged 40 to 69 at study entry between 2006 and 2010, with follow‐up through mid‐2015. assessed association subsequent PC using multivariable Cox regression analyses, adjusting age assessment, ethnic group, region, smoking status, alcohol drinking...
B7 homolog 3 (B7-H3) is an immunomodulatory molecule that highly expressed in prostate cancer (PCa) and belongs to the superfamily, which includes PD-L1. Immunotherapies (antibodies, antibody-drug conjugates, chimeric antigen receptor T cells) targeting B7-H3 are currently clinical trials; therefore, elucidating molecular immune microenvironment correlates of expression may help guide trial design interpretation. The authors tested interconnected hypotheses associated with genetic racial...
Abstract Background Prostate cancer (PCa) is a clinically heterogeneous disease. The creation of an expression‐based subtyping model based on prostate‐specific biological processes was sought. Methods Unsupervised machine learning gene expression profiles from prospectively collected primary prostate tumors (training, n = 32,000; evaluation, 68,547) used to create classifier (PSC) basal versus luminal cell patterns and other signatures relevant PCa biology. Subtype molecular pathways...
No AccessJournal of UrologyAdult Urology1 May 2020Surgical versus Medical Castration for Metastatic Prostate Cancer: Use and Overall Survival in a National CohortThis article is commented on by the following:Editorial Comment Adam B. Weiner, Jason E. Cohen, John O. DeLancey, Edward M. Schaeffer, Gregory Auffenberg WeinerAdam Weiner *Correspondence: 676 N. Saint Clair St., Arkes 23-028, Chicago, Illinois 60611 telephone: 312-503-5359; FAX: 312-908-7275; E-mail Address: [email protected]...