A5021547690- Cancer Cells and Metastasis
- Ferroptosis and cancer prognosis
- Women's cancer prevention and management
- Breast Cancer Treatment Studies
- S100 Proteins and Annexins
- Inflammatory mediators and NSAID effects
- Science, Research, and Medicine
- Fatty Acid Research and Health
- Acute Myeloid Leukemia Research
- Cancer, Lipids, and Metabolism
- Estrogen and related hormone effects
- Immune Cell Function and Interaction
- Virus-based gene therapy research
- Cardiovascular Disease and Adiposity
- Nutrition, Genetics, and Disease
- HER2/EGFR in Cancer Research
- Cancer Immunotherapy and Biomarkers
- Acute Lymphoblastic Leukemia research
- Cervical Cancer and HPV Research
- Childhood Cancer Survivors' Quality of Life
- Adipose Tissue and Metabolism
Universidad Autónoma de Guadalajara
2024
Universidad de Guadalajara
2018-2022
Mexican Social Security Institute
2022
Hospital Civil de Guadalajara
2018
<b><i>Objective: </i></b>The aim of this study was to analyze dietary &#x03C9;-6:&#x03C9;-3 polyunsaturated fatty acid (PUFA) ratio and its association with adiposity serum adiponectin levels in a Mexican population. <b><i>Methods:</i></b> In cross-sectional study, individuals BMI ≥ 18.5 kg/m<sup>2</sup>, were classified using four methods measure adiposity. Parameters body composition measured by InBody 3.0. Diet intake...
Worldwide breast cancer ranks first in mortality and incidence rates women over 20 years old. Rather than one disease, is a heterogeneous group of diseases that express distinct molecular profiles. Neoadjuvant chemotherapy an important therapeutic strategy for patients independently their subtype, with the drawback resistance development. In addition, has adverse effects combined could contribute to lower overall survival. Although great efforts have been made find diagnostic prognostic...
Background:Currently, one of the most used strategies for treatment newly diagnosed patients with breast cancer is neoadjuvant chemotherapy based on application taxanes and anthracyclines. However, despite high number who develop a complete pathological clinical response, resistance relapse following this therapy continue to be challenge. As component innate immune system, cytotoxic function Natural Killer (NK) cells plays an important role in elimination tumor cells. NK systemic remains...
Breast cancer ranks first in terms of mortality and incidence rates worldwide among women. The HER2+ molecular subtype is one the most aggressive subtypes; its treatment includes neoadjuvant chemotherapy use a HER2 antibody. Some patients develop resistance despite positive results obtained using this therapeutic strategy.To identify prognostic markers for survival patients.Patients treated with were assigned to sensitive resistant groups based on their response. Differentially expressed...
Despite the improvement in survival acute lymphoblastic leukemia (ALL), there are still cases with evasion of chemotherapy-induced apoptosis. The IKK/NF-κB signaling pathway contributes to antiapoptotic gene expression. Pentoxifylline (PTX) inhibits IkB phosphorylation, blocking NF-κB and activity.
Beta-2 Human papillomaviruses 38b, 107, and 122 have been frequently found in cervical cancer samples western Mexico. Because their E6/E7 genes functions are not fully elucidated, we deepen into transformation capabilities. To achieve this goal, primary human fibroblasts (FB) were transduced with genotype-specific viral particles. Additionally, from HPVs 16 18 included as controls. All E6/E7-cell models increased lifespan; however, it is important to highlight that FB-E6/E7-122 showed growth...
Abstract Neoadjuvant chemotherapy is one important therapeutic strategy for breast cancer with the drawback of resistance development. Chemotherapy has adverse effects that combined could contribute to lower overall survival. This work aimed evaluate molecular profile patients who received neoadjuvant discover differentially expressed genes (DEGs) be used as biomarkers response and Breast were enrolled in this study according their pathological assigned sensitive or resistant. To DEGs, GO,...
Breast cancer currently represents one of the largest public health problems in Mexico and world, since it is first cause death due to neoplasia women over 25 years. The official statistical records correspond 1982, worldwide 1926. However, very ancient civilizations denote their existence for millennia. This review summarizes part history breast cancer, from Egyptians present day, including beliefs that were held about this disease, as well contributions great scientists who helped...