A5001729240- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Tuberculosis Research and Epidemiology
- Cardiovascular Disease and Adiposity
- Immunodeficiency and Autoimmune Disorders
- Inflammasome and immune disorders
- Infective Endocarditis Diagnosis and Management
- Antimicrobial Resistance in Staphylococcus
- Mycobacterium research and diagnosis
- Patient Safety and Medication Errors
- Pharmaceutical Practices and Patient Outcomes
- Respiratory viral infections research
- Antifungal resistance and susceptibility
- Liver physiology and pathology
- Connective Tissue Growth Factor Research
- Peroxisome Proliferator-Activated Receptors
- TGF-β signaling in diseases
- Pharmacovigilance and Adverse Drug Reactions
- Genomics, phytochemicals, and oxidative stress
- Sports Performance and Training
- Vitamin C and Antioxidants Research
- Influenza Virus Research Studies
- Mosquito-borne diseases and control
- Glutathione Transferases and Polymorphisms
- Thermal Regulation in Medicine
Universidad de Guadalajara
2007-2024
<b><i>Objective: </i></b>The aim of this study was to analyze dietary &#x03C9;-6:&#x03C9;-3 polyunsaturated fatty acid (PUFA) ratio and its association with adiposity serum adiponectin levels in a Mexican population. <b><i>Methods:</i></b> In cross-sectional study, individuals BMI ≥ 18.5 kg/m<sup>2</sup>, were classified using four methods measure adiposity. Parameters body composition measured by InBody 3.0. Diet intake...
An adequate immune and antioxidant response is a key to the resolution of sepsis. Heme oxygenase-1 (HMOX1) stress protein with polymorphic (GT)n repeat in its gene promoter that regulates expression oxidative injury, such as present HMOX1 rate-limiting enzyme heme degradation, breakdown products, CO, Fe, bilirubin, are considered be biologically active metabolites direct or indirect anti-inflammatory properties. In this study, we investigated inflammatory relationship levels polymorphism...
Evaluate the type and severity of potential drug-drug interactions identify risk factors involved, in pediatric patients admitted a hospital setting.Transversal retrospective analytical study was carried out with hospitalized from Hospital West Mexico, second third level. The included were ≤18 years old children wards; those at emergency room, neonatal intermediate intensive therapy units not included. Medical prescriptions reviewed taking into consideration anthropometric characteristics,...
Obesity is characterized by low-grade chronic inflammation and an excess of adipose tissue. The ASC gene encodes a protein that part the NLRP3 inflammasome, cytosolic multiprotein complex associated with metabolic alterations. To our knowledge, there no evidence regarding activity in obese adults response to lifestyle modifications. evaluate effect hypocaloric diet moderate-intensity structured exercise intervention on expression inflammatory markers adults. Thirty-seven individuals aged 25...
Metabolically healthy (MH) and metabolically unhealthy (MUH) phenotypes can be present in any subject independently of their body mass index (BMI). However, factors related to the presence these are poorly understood. Therefore, aim this cross-sectional study is describe prevalence characteristics associated with MH MUH Mexican subjects different BMI categories. Anthropometric biochemical parameters were evaluated after 12 h fasting. HMW (High Molecular Weight) adiponectin insulin levels...
Paraoxonase 1 (PON1), a high-density lipoprotein-associated antioxidant enzyme, hydrolyzes several organophosphate pesticides and oxidized lipids. The PON1 Q192R polymorphism affects the catalytic efficiency is considered risk factor for pesticide intoxication cardiovascular disease (CVD) but association not consistent between individuals or populations. We aimed to study of with CVD in coffee harvesters central Colombia. Demographics were collected from 205 subjects via standardized...
Single nucleotide polymorphisms (SNPs) in the ADIPOQ gene could explain adiponectin level. However, knowledge about influence of genetic and lifestyle factors is not sufficient. The aim was to analyze whether effect -11391G/A SNP modulated by Mexican subjects.A cross-sectional study performed which 394 participants were analyzed. Genetic, anthropometric, biochemical, dietary, clinical physical activity parameters measured. Statistical analysis with SPSSv19 software.The distribution genotypes...
Genetic predisposition to cardiovascular risk may vary between different ethnic groups. We studied the effect of FABP2 A54T polymorphism on biochemical and anthropometric factors in 114 obese Mexican subjects. The mean age patients was 36.8±13.3 years. Insulin resistance present 47%, hypercholesterolaemia 49% hyper-triglyceridaemia 45%. Frequency genotype 39% AA, 54.8% AT 6.2% TT. AT/TT group showed an increase body mass index (34±7.1 vs. 31±4.8 kg/m 2 ), waist circumference (101±15.7...
As a pleiotropic protein, transforming growth factor (TGF)-beta induces its effects by binding to Ser/Thr kinase receptor type II and then recruiting activating I, which is phosphorylated activates Smads that transduce the signal nucleus.In this work, authors blocked TGF-beta1 transduction pathway via delivery of dominant-negative receptor-II (DeltaCyTbRII)-cDNA lacking intracytoplasmic domain activity. Thus, Cos-1 hepatic stellate cells were cotransfected with pCMV5-DeltaCyTbRII...
Latent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with processing (TAP1) protein involved the transport from cytoplasm endoplasmic reticulum means association MHC class I molecules. It plays fundamental role response,...
Infective endocarditis is a disease characterised by heart valve lesions, which exhibit extracellular matrix proteins that act as physical barrier to prevent the passage of antimicrobial agents. The genus Candida has acquired clinical importance given it increasingly being isolated from cases nosocomial infections.To evaluate activity caspofungin compared liposomal amphotericin B against albicans in experimental infective endocarditis.Wistar rats underwent surgical intervention and infection...
Abstract Background Recurrent respiratory papillomatosis (RRP) is a tract disease that affects children and adults characterized by the recurrent proliferation of multiple papillomas. The etiologic agent human papillomavirus, mainly genotypes 6 11. Furthermore, polymorphisms in TAP1 appear to influence selection antigenic peptides transport process rough endoplasmic reticulum, for their subsequent presentation T lymphocytes, an essential against viral diseases tumor processes. Previous...
Abstract Background The ACTN3 gene is primarily expressed in fast skeletal muscle fibres. A common nonsense polymorphism this R577X (rs1815739), which causes an absolute deficiency of α‐actinin‐3 protein and alterations metabolism. Considering metabolic are influenced by nutrition genetic factors, as well lifestyle we hypothesise a possible association the with alterations. Methods In cross‐sectional study, 397 adults met inclusion criteria. Body composition was measured electrical...
Candida albicans is the most common fungal pathogen known to cause endovascular infections, such as vascular catheter sepsis, infections of prostheses and infective endocarditis. A C. isolate was used determine apoptotic potential fungus in a rat endocarditis model. This study confirms ability induce apoptosis myocardial tissue.
Abstract Background: Obesity is characterized by low-grade chronic inflammation and an excess of adipose tissue. The ASC gene encodes a protein that part the NLRP3 inflammasome, cytosolic multiprotein complex associated with metabolic alterations. To our knowledge, there no evidence regarding activity in obese adults response to lifestyle modifications. Purpose: evaluate effect hypocaloric diet moderate-intensity structured exercise intervention on expression inflammatory markers adults....
Abstract Background Several factors are related to lifestyle behaviors, like physical inactivity and unbalanced diets, which increase the risk of developing obesity thus represent an important health problem worldwide. Obesity is characterized by low-grade chronic inflammation excess adipose tissue. The ASC protein part NLRP3 inflammasome, a cytosolic multiprotein complex that associated with metabolic alterations. Purpose To evaluate effect moderate-intensity structured exercise...