Manju Bala

ORCID: 0000-0002-1934-8272
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Research Areas
  • Reproductive tract infections research
  • Bacterial Infections and Vaccines
  • Syphilis Diagnosis and Treatment
  • HIV Research and Treatment
  • Virology and Viral Diseases
  • HIV/AIDS Research and Interventions
  • HIV/AIDS drug development and treatment
  • Adolescent Sexual and Reproductive Health
  • Immunotherapy and Immune Responses
  • Hepatitis C virus research
  • Clostridium difficile and Clostridium perfringens research
  • Blood groups and transfusion
  • Cervical Cancer and HPV Research
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Hepatitis B Virus Studies
  • Respiratory Support and Mechanisms
  • Viral Infections and Vectors
  • Immune Cell Function and Interaction
  • vaccines and immunoinformatics approaches
  • SARS-CoV-2 and COVID-19 Research
  • HIV-related health complications and treatments
  • Tuberculosis Research and Epidemiology
  • Genital Health and Disease
  • Mosquito-borne diseases and control
  • Animal Virus Infections Studies

Institute of Medical Sciences
2024

Central Institute of Post-Harvest Engineering and Technology
2023

National Center for Disease Control
2020-2022

Ahmadu Bello University
2022

National Center for Emerging and Zoonotic Infectious Diseases
2022

Punjab Agricultural University
2021

Kurukshetra University
2016-2021

All India Institute of Medical Sciences Rishikesh
2021

University of Jammu
2020

Government Medical College, Amritsar
2020

Antimicrobial resistance (AMR) in Neisseria gonorrhoeae seriously compromises the management and control of gonorrhea.• In vitro clinical N. to extended-spectrum cephalosporins (ESCs), last-line treatment for gonorrhea, have been reported from many, particularly well-resourced, settings globally.• The World Health Organization (WHO) Global Gonococcal Surveillance Programme (GASP) is key monitoring AMR trends, identifying emerging AMR, informing regular refinements guidelines public health...

10.1371/journal.pmed.1002344 article EN cc-by PLoS Medicine 2017-07-07

Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a major concern worldwide. It has been recently feared that the bla TEM-1 gene is, via TEM-135, evolving into an extended-spectrum β-lactamase (ESBL), which could degrade all cephalosporins including ceftriaxone. The aims of present study were to characterize TEM genes, types plasmids, degradation ampicillin by TEM-135 compared TEM-1, and perform molecular epidemiological typing β-lactamase-producing N. strains internationally....

10.1186/1471-2334-14-454 article EN cc-by BMC Infectious Diseases 2014-08-22

With the quick spread of pandemic disease, many individuals have lost their lives across different parts world. So, need for a novel approach or model to overcome problem becomes necessity. In this paper, mechanism is proposed called DBCMS (Drone Based Covid-19 Medical Service) safety medical employees who are prone infection. The can effectively improve treatment process patients. Drones nowadays commonly used in field emergency situations. paper uses drone service reduce risk infection...

10.1016/j.jnlssr.2020.06.011 article EN cc-by-nc-nd Journal of Safety Science and Resilience 2020-07-02

Objective The aim of the present study was to retrospectively analyse data reported on antimicrobial resistance (AMR) in Neisseria gonorrhoeae six South-East Asia Region countries from 2009 2012 following revitalisation WHO global Gonococcal Antimicrobial Surveillance Program (GASP). Methods AMR were generated for 7 antibiotics 4675 isolates 18 focal point laboratories using calibrated dichotomous sensitivity (CDS) or Clinical and Laboratory Standards Institute (CLSI) methods minimal...

10.1136/sextrans-2012-050904 article EN Sexually Transmitted Infections 2013-11-15

<ns4:p><ns4:bold>Background: </ns4:bold>India first detected SARS-CoV-2, causal agent of COVID-19 in late January 2020, imported from Wuhan, China. From March 2020 onwards, the importation cases countries rest world followed by seeding local transmission triggered further outbreaks India.</ns4:p><ns4:p> <ns4:bold>Methods: </ns4:bold>We used ARTIC protocol-based tiling amplicon sequencing SARS-CoV-2 (n=104) different states India using a combination MinION and MinIT Oxford Nanopore Technology...

10.12688/wellcomeopenres.16119.1 preprint EN cc-by Wellcome Open Research 2020-08-03

The adequacy of the World Health Organization's syndromic approach for diagnosis and management sexually transmitted diseases (STDs), especially at primary health centers (PHCs) other levels, is still debatable in different settings India requires validation.A cross-sectional study was carried out women attending peripheral government clinics Delhi order to (1) enumerate their self-reported reproductive tract infection (RTI)/sexually (STI) symptoms; (2) assess clinical status; (3) determine...

10.1016/j.ijid.2008.11.021 article EN publisher-specific-oa International Journal of Infectious Diseases 2009-02-24

Despite the progressive increase of antimicrobial resistance Neisseria gonorrhoeae worldwide, there are limited reports alternative remedies from plants.The aim current study was to screen 3 plants, Ocimum sanctum, Drynaria quercifolia, and Annona squamosa, for activity against gonorrhoeae.By disc diffusion method, extracts these plants were screened gonorrhoeae; their calculated as percentage inhibition compared with penicillin ciprofloxacin.The all caused clinical isolates World Health...

10.1097/01.olq.0000152821.23777.90 article EN Sexually Transmitted Diseases 2005-01-24

10.1016/j.ijantimicag.2008.07.022 article EN International Journal of Antimicrobial Agents 2008-09-26

To monitor the trend of antimicrobial susceptibility Neisseria gonorrhoeae isolates from 2002 to 2006 in New Delhi, India under Gonococcal Antimicrobial Susceptibility Programme and document emergence any new resistance.Antimicrobial 382 N. clinical cases males females penicillin, tetracycline, ciprofloxacin, spectinomycin ceftriaxone was determined by disc diffusion technique, using WHO reference strains as controls interpretative criteria. MICs were Etests.A significant increasing...

10.1093/jac/dkm238 article EN Journal of Antimicrobial Chemotherapy 2007-06-29

SUMMARY The study was carried out in symptomatic and asymptomatic women attending peripheral health centres to determine the laboratory prevalence of sexually transmitted infection (STI), reproductive tract (RTI) HIV. A total 4090 four groups were subjected general speculum examination screened for aetiological agents RTI/STI by standard techniques. main complaint vaginal discharge, singly (11·2%) or along with other symptoms (49·0%). Prevalence RTI/STI/HIV 36·8%. Agents RTIs harboured 24·3%...

10.1017/s0950268807000088 article EN Epidemiology and Infection 2007-12-17

Abstract Background Knowledge on antimicrobial drug resistance and genetic characteristics of Neisseria gonorrhoeae isolates circulating in India, Pakistan, Bhutan is sorely lacking. In this paper, we describe the prevalence molecular N. from 2007–2011. Methods Antimicrobial susceptibility β-lactamase production were tested for 65 N . India (n=40), Pakistan (n=18) (n=7) using Etest methodology (eight antimicrobials) nitrocefin solution, respectively. Resistance determinants, i.e. penA , mtrR...

10.1186/1471-2334-13-35 article EN cc-by BMC Infectious Diseases 2013-01-24

Background Recent WHO guidelines recommend dual therapy with ceftriaxone or cefixime plus azithromycin for gonorrhea. Azithromycin in combination gentamicin spectinomycin has been recommended treatment failure cases. Due to emergence of multi-drug resistant (MDR) and extensively-drug (XDR) Neisseria gonorrhoeae strains, it is important look efficacy these combinations also others that might be used future. Therefore, we aimed evaluate vitro synergy 21 including current alternative regimens...

10.1371/journal.pone.0193678 article EN cc-by PLoS ONE 2018-03-06
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