- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Force Microscopy Techniques and Applications
- Advanced Nanomaterials in Catalysis
- Biosensors and Analytical Detection
- Nanofabrication and Lithography Techniques
- Molecular Junctions and Nanostructures
- Education and Learning Interventions
- Analytical chemistry methods development
- Laser-induced spectroscopy and plasma
- Nanocluster Synthesis and Applications
- Alzheimer's disease research and treatments
- Analytical Chemistry and Sensors
- Advanced Biosensing Techniques and Applications
- Electrochemical Analysis and Applications
- Plasmonic and Surface Plasmon Research
- Nanoparticle-Based Drug Delivery
- Educational Systems and Policies
- Nanoparticles: synthesis and applications
- Electrochemical sensors and biosensors
- Nanoplatforms for cancer theranostics
- Microfluidic and Bio-sensing Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Graphene and Nanomaterials Applications
- Near-Field Optical Microscopy
University of Seoul
2015-2024
Sookmyung Women's University
2023-2024
Government of the Republic of Korea
2008-2020
Seoul Institute
2019-2020
Institut Pasteur Korea
2020
Institut Pasteur
2020
Lawrence Berkeley National Laboratory
2011-2017
Korean Educational Development Institute
2016-2017
Seoul National University
2006-2015
Gwangju Health University
2015
The health threat of arsenic is well-known, and the U.S. EPA recommends maximum contaminant level to be 0.01 ppm or less for in drinking water. Therefore, advanced treatment processes are needed finished water meet required regulations. Adsorption considered a expensive procedure that safer handle than precipitation, ion exchange, membrane filtration. Activated alumina (AA) most commonly used adsorbent removal from aqueous solutions. However, conventional porous solids including AA have...
DNA-templated metallization has emerged as an efficient strategy for creating nanoscale-metal DNA hybrid structures with a desirable conformation and function. Despite the potential of DNA–metal hybrids, their use combinatory therapeutic agents rarely been examined. Herein, we present simple approach fabricating multipurpose superstructure that serves photoimmunotherapy agent. Specifically, adsorb locally concentrate Au ions onto superstructures through induced local reduction, resulting in...
Obtaining single-molecular-level fingerprints of biomolecules and electron-transfer dynamic imaging in living cells are critically demanded postgenomic life sciences medicine. However, the possible solution called plasmonic resonance energy transfer (PRET) spectroscopy remains challenging due to fixed scattering spectrum a nanoparticle limited multiplexing. Here, multiplexed metasurfaces-driven PRET hyperspectral imaging, probe biological light-matter interactions, is reported. Pixelated...
Conventional antibiotic-based treatment of bacterial infections remains one the most difficult challenges in medicine because threat multidrug resistance caused by indiscriminate abuse. To solve these problems, it is essential to develop an effective antibacterial agent that can be used at a small dose while minimizing occurrence multiple resistance. Metal–organic frameworks (MOFs), which are hyper-porous hybrid materials containing metal ions linked organic ligands, have recently attracted...
Recent progress in plasmon-based sensors has greatly overcome the limitations of conventional optical sensors, terms sensitivity, tunability, photostability, and vivo applicability, by employing nanostructured materials. In this review, we summarize three types nanosensors categorized geometries sensing platforms as plasmonic transducers, which are planar nanofilm, periodic nanoarrays, individual nanoparticles, respectively. We then introduce notable accomplishments to enhance performances...
Fixed‐effects meta‐analysis has been criticized because the assumption of homogeneity is often unrealistic and can result in underestimation parameter uncertainty. Random‐effects meta‐regression are therefore typically used to accommodate explained unexplained between‐study variability. However, it not unusual obtain a boundary estimate zero for (residual) standard deviation, resulting fixed‐effects estimates other parameters their errors. To avoid such estimates, we suggest using Bayes...
We report graphene nanopores with integrated optical antennae. demonstrate that a nanometer-sized heated spot created by photon-to-heat conversion of gold nanorod resting on membrane forms nanoscale pore self-integrated antenna in single step. The distinct plasmonic traits metal nanoparticles, which have unique capability to concentrate light into regions, yield the significant advantage parallel nanopore fabrication compared conventional sequential process using an electron beam. Tunability...
In recent nanobiotechnology developments, a wide variety of functional nanomaterials and engineered biomolecules have been created, these numerous applications in cell biology. For to fulfill their promises completely, they must be able reach biological targets at the subcellular level with high specificity. Traditionally, either nanocarrier- or membrane disruption-based method has used deliver inside cells; however, methods are suboptimal due toxicity, inconsistent delivery, low throughput,...
Heavy metal ions are known to cause environmental pollution and several human diseases because of their inherent toxicity. Among them, Cu2+ is an essential element for the body, but its continuous exposure accumulation may adverse effects. Thus, copper ion levels in aquatic environments strictly regulated by international standards. Herein, we demonstrate a simple optical method detecting using plasmonic sugar nanoprobes (PSNs) composed gold nanoparticles polysaccharides. Gold precursors...
The detection and characterization of protein aggregates are critical in terms advanced diagnostic applications investigations stability. A variety analytical methods (e.g., circular dichroism, size exclusion chromatography, fluorescence microscopy) have been used this regard, but they limited the trace structural evolution aggregation. Here we report gold nanoparticle (AuNP)-based highly sensitive colorimetric temporal superoxide dismutase (SOD1) implicated pathology amyotrophic lateral...
We report core–satellites (Au–Ag) coupled plasmonic nanoassemblies based on bottom-up, high-density assembly of molecular-scale silver nanoparticles a single gold nanoparticle surface, and demonstrate direct observation quantification enhanced plasmon coupling (i.e., intensity amplification apparent spectra shift) in particle level. also explore metal ion sensing capability our core–satellites, which enabled at least 1000 times better detection limit as compared to that nanoparticle. Our...
One of the primary pathological hallmarks Alzheimer's diseases (AD) is amyloid-β (Aβ) aggregation and its extracellular accumulation. However, current in vitro Aβ assays require time-consuming labor-intensive steps, which delay process drug discovery understanding mechanism induced neurotoxicity. Here, we propose a rapid detection method for studying inhibition under an optimized acidic perturbation condition by dual functions gold nanoplasmonic particles (GNPs): (1) catalytic activator (2)...
Abstract Controlled assembly of colloidal nanoparticles onto solid substrates generally needs to overcome their thermal diffusion in water. For this purpose, several techniques that are based on chemical bonding, capillary interactions with substrate patterning, optical force, and optofluidic heating light‐absorbing proposed. However, the direct generic without linkers patterning still remains challenging. Here, photothermal convection lithography is proposed, which allows rapid placement...
Emerging as substantial concerns in the ecosystem, submicron plastics have attracted much attention for their considerable hazards. However, effect and even amount environment remain unclear. Establishing a substantive analytic platform is essential to expand understanding of nanoplastics. issues diffusion detection limit that arise from ultradiluted concentration extremely small scales nanoplastics leave significant technical hurdles analyze nanoplastic pollutants. In this study, we obtain...
This study introduces a facile method for fabricating hydrophilic 3D-network hydrogels, integrating plasmonic gold nanoparticles to boost solar absorption, enhancing evaporation rates and efficiency 1.6 kg m −2 h −1 77%, respectively.
Rapid, sensitive, inexpensive point-of-care molecular diagnostics are crucial for the efficient control of spreading viral diseases and biosecurity global health. However, gold standard, polymerase chain reaction (PCR) is time-consuming expensive needs specialized testing laboratories. Here, we report a low-cost yet fast, selective, sensitive Plasmonic Optical Wells-Based Enhanced Rate PCR: POWER–PCR. We optimized optofluidic design 3D plasmonic optical wells via computational simulation...
Trace detection and physicochemical characterization of protein aggregates have a large impact in understanding diagnosing many diseases, such as ageing-related neurodegeneration systemic amyloidosis, for which the formation is one pathological hallmarks. Here we demonstrate an innovative label-free method detecting characterizing small amounts early stage using Raman active nanofluidic device. Sub-micrometre channels formed by novel elastomeric collapse technique enable separation...