- Exercise and Physiological Responses
- Cardiovascular and exercise physiology
- Muscle metabolism and nutrition
- Adipose Tissue and Metabolism
- Antioxidant Activity and Oxidative Stress
- Physical Activity and Health
- Vitamin C and Antioxidants Research
- Diet and metabolism studies
- Heart Rate Variability and Autonomic Control
- Sports injuries and prevention
- Mitochondrial Function and Pathology
- Cardiovascular Health and Disease Prevention
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Thermoregulation and physiological responses
- Coenzyme Q10 studies and effects
- Sports Performance and Training
- Adipokines, Inflammation, and Metabolic Diseases
- Electron Spin Resonance Studies
- Cardiac Health and Mental Health
- Epigenetics and DNA Methylation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cystic Fibrosis Research Advances
- Physical Education and Training Studies
- Biochemical Acid Research Studies
- Obesity, Physical Activity, Diet
University of Ulster
2015-2024
Sport Ireland
2010-2022
Health Affairs
2020
The Behaviouralist (United Kingdom)
2020
OGT Amenity (Ireland)
2019
Northumbria University
2016
Maastricht University
2016
Newcastle University
2016
Ulster Hospital
2007-2009
Queen's University Belfast
2009
This investigation examined the impact of Montmorency tart cherry concentrate (MC) on physiological indices oxidative stress, inflammation and muscle damage across 3 days simulated road cycle racing. Trained cyclists (n = 16) were divided into equal groups consumed 30 mL MC or placebo (PLA), twice per day for seven consecutive days. A simulated, high-intensity, stochastic cycling trial, lasting 109 min, was completed 5, 6 7. Oxidative stress measured from blood samples collected at baseline...
This study investigated Montmorency tart cherry concentrate (MC) supplementation on markers of recovery following prolonged, intermittent sprint activity. Sixteen semi-professional, male soccer players, who had dietary restrictions imposed for the duration study, were divided into two equal groups and consumed either MC or placebo (PLA) eight consecutive days (30 mL twice per day). On day 5, participants completed an adapted version Loughborough Intermittent Shuttle Test (LISTADAPT). Maximal...
The impact of Montmorency tart cherry (Prunus cerasus L.) concentrate (MC) on physiological indices and functional performance was examined following a bout high-intensity stochastic cycling. Trained cyclists (n = 16) were equally divided into 2 groups (MC or isoenergetic placebo (PLA)) consumed 30 mL supplement, twice per day for 8 consecutive days. On the fifth supplementation, participants completed 109-min cycling trial designed to replicate road race demands. Functional (maximum...
Abstract We examined the extent to which apnoea‐induced extremes of oxygen demand/carbon dioxide production impact redox regulation cerebral bioenergetic function. Ten ultra‐elite apnoeists (six men and four women) performed two maximal dry apnoeas preceded by normoxic normoventilation, resulting in severe end‐apnoea hypoxaemic hypercapnia, hyperoxic hyperventilation designed ablate hypoxaemia, hyperoxaemic hypercapnia. Transcerebral exchange ascorbate radicals (by electron paramagnetic...
BACKGROUND: Many strategies are in use with the intention of preventing or minimizing delayed onset muscle soreness and fatigue after exercise. Cold-water immersion, water temperatures less than 15 °C, is currently one most popular interventional used OBJECTIVES: To determine effects cold-water immersion management SEARCH METHODS: In February 2010, we searched Cochrane Bone, Joint Muscle Trauma Group Specialised Register, Central Register Controlled Trials (The Library (2010, Issue 1),...
This study examined the effects of beetroot juice (BTJ) on recovery between two repeated-sprint tests. In an independent groups design, 20 male, team-sports players were randomized to receive either BTJ or a placebo (PLA) (2 × 250 mL) for 3 days after initial repeated sprint test (20 30 m; RST1) and second (RST2), performed 72 h later. Maximal isometric voluntary contractions (MIVC), countermovement jumps (CMJ), reactive strength index (RI), pressure-pain threshold (PPT), creatine kinase...
The beneficial effects of exercise in patients with type 1 diabetes (T1D) are not fully proven, given that it may occasionally induce acute metabolic disturbances. Indeed, the disturbances associated sustained lead to worsening control unless great care is taken adjust carbohydrate intake and insulin dosage. In this work, pre- post-exercise metabolites were analyzed using a 1H-NMR GC-MS untargeted metabolomics approach assayed serum. We studied ten men T1D eleven controls matched for age,...
Aim Despite recognition that regular physical activity is essential for good health, many children do not accumulate sufficient daily activity. The aim of this study was to examine the effect a classroom‐based break on accelerometer‐determined moderate‐to‐vigorous intensity (MVPA) and adiposity in primary school children. Methods One hundred twenty from seven schools Northern Ireland participated study. In each school, one class randomly assigned an intervention group another control group....
High-intensity exercise damages mitochondrial DNA (mtDNA) in skeletal muscle. Whether MitoQ - a redox active targeted quinone can reduce exercise-induced mtDNA damage is unknown. In double-blind, randomized, placebo-controlled design, twenty-four healthy male participants consisting of two groups (placebo; n = 12, MitoQ; 12) performed an trial 4 x 4-min bouts at 90–95% heart rate max. Participants completed acute (20 mg or placebo 1-h pre-exercise) and chronic (21 days supplementation)...
There is no direct evidence to support the contention that contracting skeletal muscle and/or associated vasculature generates free radicals in exercising humans. The unique combination of isolated quadriceps exercise and measurement femoral arterial venous radical concentrations with use electron paramagnetic resonance (EPR) spectroscopy enabled this assumption be tested seven healthy men. Application ex vivo spin trapping using α-phenyl- tert-butylnitrone (PBN) resulted detection oxygen-...
Abstract Exercise‐induced deoxyribonucleic acid (DNA) damage is often associated with an increase in free radicals; however, there a lack of evidence examining the two parallel. This study tested hypothesis that high‐intensity exercise has ability to produce radicals may be capable causing DNA damage. Twelve apparently healthy male subjects (age: 23 ± 4 years; stature: 181 8 cm; body mass: 80 9 kg; and V O 2max : 49 5 ml/kg/min) performed three min consecutive incremental stages (40, 70,...
Abstract Background Cinnamon has been shown to delay gastric emptying of a high-carbohydrate meal and reduce postprandial glycemia in healthy adults. However, it is dietary fat which implicated the etiology associated with obesity, type 2 diabetes cardiovascular disease. We aimed determine effect 3 g cinnamon ( Cinnamomum zeylanicum ) on GE, lipemic glycemic responses, oxidative stress, arterial stiffness, as well appetite sensations subsequent food intake following high-fat meal. Methods A...