Background: Monosomy 18p is a chromosomal disorder resulting from the deletion of short arm chromosome 18. While lot cases result partial 18p, only few reported are caused by whole 18 due to unbalanced translocations occurring between chromosomes 13 and (13;18). 18p- monosomy presents with variety clinical manifestations, including facial dysmorphism, intellectual disability, stature, among others. Case presentation: Here, we report case one-year-old girl an translocation (45, XX, t(13;18)...

Introduction. Infective mononucleosis is most commonly caused by Epstein-Barr virus (EBV), and in smaller percentage cytomegalovirus (CMV). Objective. The aim of this paper was to determine the clinical laboratory differences between EBV CMV infectious children. Methods. Cohort retrospective analytical research conducted. We used data from medical history six years period monitored anamnestic data, frequency inspection palpation obtained during physical examination, several tests, abdomen...

Given that oxidative stress represents an important etiological factor in the pathogenesis of psoriasis, aim this study was to assess effects different therapeutic approaches, methotrexate, secukinumab, and ustekinumab on systemic biomarkers psoriatic patients. This involved 78 patients, divided into group treated with methotrexate (23 patients), secukinumab (28 (27 15 healthy controls. Oxidative (index lipid peroxidation measured as TBARS, nitrites (NO

This study utilizes data from the fourth National Health Survey conducted in 2019. Republic of Serbia, aiming to contribute a deeper understanding factors influencing mobility elderly population. It examines sociodemographic and psychosocial associated with functional limitations older adults. By analyzing variables such as age, gender, marital status, education, income, social support, mental health, seeks explain their impact on prevalence walking limitations.Questionnaires were employed...

Background and Objectives: Atherosclerosis is one of inflammatory bowel disease's most significant cardiovascular manifestations. This research aimed to examine the relationship between biochemical, haemostatic, immune parameters atherosclerosis ulcerative colitis patients its platelet aggregation. Materials Methods: A clinical, observational cross-sectional study was performed, during which tested were compared in experimental control groups. The divided into four first group had 25 who...

Introduction. Schimke immuno-osseous dysplasia (SIOD) is a rare autosomal recessive multisystem disorder associated with biallelic mutations of the SMAR-CAL1 gene. Vascular central nervous system complications in form Moyamoya syndrome (MMS) have been reported as comorbidity nearly half patients clinically presenting severe migraine-like headaches, transient ischemic attacks (TIA), and or hemorrhagic infarctions. We present an illustrative case infantile SIOD MMS, review latest diagnostic...

Introduction/Objective. Strict gluten-free diet for life is the only treatment patients with coeliac disease. Limited selection of food options can affect their quality and cause problems in acceptance by peers. The aim was to examine subjective experience children adolescents disease obtain a comprehensive representation physical mental impairments social functioning compared healthy Methods. study conducted as cross-sectional study. It included 116 respondents aged 5?18 years similar age...

Background. Acute hemorrhagic edema of infancy (AHEI) is a rare vasculitis, which presents dramatically as palpable purpuric skin lesions on the limb, face and auricles, with swelling these parts low-grade fever, in children up to 2 years age. To date, approximately 400 cases have been described literature. The etiology remains mostly unknown. With or without treatment, AHEI goes spontaneous recovery within 1-3 weeks, usually any complications. our knowledge, compartment syndrome...

Introduction/Objective. Child abuse is a significant public health problem in modern society. Many cases of violence against children remain undetected. Serbia has no official protocols for medical examination abused children. The aim the study an analysis social, clinical and radiological characteristics physical under three years age that required hospital treatment. Methods. This retrospective included 98 physically injured admitted to University Children?s Hospital period from 2013 2015,...

Abstract Tromboses are considered to be rare disorders in the pediatric population. However, they occur more frequently during neonatal period. Potential risk factors for thrombosis onset include frequent use of peripheral, umbilical or central venous / arterial catheters, inflammation, disseminated intravascular coagulation, liver disorders, hypovolemia, asphyxia, congenital heart disease, polycythemia and dehydration. On seventh day life male premature infant born 29th 30th gestation week,...

A novel condition named multisystem inflammatory syndrome has raised the alarm worldwide and is leading to severe illness long-term effects in post-COVID era. This includes infection with fever, abdominal symptoms, acute cardiac injury, shock. It similarities forms of Kawasaki disease (KD). In this study, we present a case 20-year-old male patient associated COVID-19 who was successfully treated plasmapheresis, immunoglobulins, steroids for 4 h/day without heparinization or ultrafiltration....

ABSTRACT Secondary haemophagocytic lymphohistiocytosis (SHFLH) is a rare, potentially fatal disorder, most commonly caused by the Epstein–Barr virus. It characterized neoplastic proliferation of cells that belong to monocyte–macrophage system and varied clinical expression. A girl aged 3 years 7 months was hospitalized due continuing high febricity, yellow skin colouring, hepatosplenomegaly cytopenia in complete blood count (CBC). Four weeks before hospitalization, she had lacunar angina...

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

Objective. Description of clinical and laboratory characteristics immune thrombocytopenic purpura in children, treatment choice therapeutic response. Methods. Retrospective study with data from medical records 87 patients both sexes, aged up to 16 years, hospitalized at the Pediatric Clinic, Clinical Center, Kragujevac, 01/10/2006 01/10/2012. All underwent a examination (history, physical examination) (complete blood count, haemostatic tests - prothrombin time, International normalized ratio...

Introduction. Streptococcus pneumoniae is the second most common cause of meningitis in children, producing more serious complications than other bacteria. infections are a rare trigger glomerulonephritis. We presented case glomerulonephritis developing concurrently with young male child. Case report. Gross haematuria, significant proteinuria, hypertension and decreased level C3 alongside signs central nervous system involvement occurred patient 5 years 3 months age. Spontaneous resolution...

Introduction. After the contact with a patient suffering from tuberculosis (TB), previously healthy children have 1%?16% possibility to develop disease. TB diagnosis in is not easy confirm so 15%?25% of cases remain undiagnosed. Case report. A 15-yearold- boy was hospitalized productive cough, pain right flank area, fever, and fatigue, loss appetite night sweats. One boy's uncles cured tuberculosis, another uncle had active both them were boy, but they did live same household. During...

Abstract In diagnosing the aspiration of foreign body (AFB) in children most important are: medical history, clinical signs and positive radiography lungs. Common dilemmas diff erential diagnosis are life-threatening asthma attacks or difficult pneumonia. Conventional rigid bronchoscopy (RB) is not recommended as a routine method. Virtual (VB) can be diagnostic tool for solving dilemmas. Fiber-optic (FOB) has therapeutic stake severe cases. Herein, we describe girl, at age 6, who was...

We present the case of a male infant who was born at 38th gestational week and product non- consanguineous marriage vaginal delivery. There no family history skin diseases in parents, but older sister also had lamellar ichthyosis. The mother received regular prenatal care. Spontaneous rupture membranes occurred approximately 2 hours prior to Apgar scores were 7/7 1st 5th minute. baby's weight 3410 grams, body length 54 cm head circumference 35 cm. Upon initial physical examination, patient...

Abstract Acute hemorrhagic edema of infancy (AHEI) is a rare vasculitis small dermal vessels with characteristic presentation in infants aged up to 24 months. It manifests as sudden occurrence palpable purpuric skin lesions, swellings hands, feet, face and auricles, mild fever. The children affected AHEI are almost always good general health normal laboratory parameters. Approximately 400 cases have been described the literature so far. However, etiology still unknown. Most evidence suggests...

Few previous studies indicated the role of oxidative stress in pathogenesis childhood idiopathic thrombocytopenic purpura (ITP), but there are little data regarding changes redox balance different forms disease, and after therapeutic procedures. We aimed to investigate values pro-oxidants antioxidative capacity various ITP before applying therapy. The research included 102 children, classified into following groups: (1) newly diagnosed (ndITP), (2) persistent ITP, (3) chronic (chITP), (4)...

Objective. The aim of this study was to estimate significance determining C-reactive protein and procalcitonin for diagnosis sepsis in febrile children. Methods. Data from medical history 82 children (30 days 16 years) who had been admitted into Intensive Care Unit Pediatric Clinic, Clinical Centre 'Kragujevac', Kragujevac, were used the study. divided two groups according specific criteria defining sepsis. Immediately after admission, we monitored erythrocyte sedimentation rate (ESR),...

Objective. The aims of this study were to find out causes urinary tract infection among children in the 5-year period and establish their antimicrobial sensitivity as well determine frequency associated congenital anomalies tract. Methods. sample included 305 patients, aged 0-14 years, both sexes, with diagnosis (UTI). According age patients they divided into five groups: newborns, infants, small, preschool school children. Patient's history documents, hospitalized on Pediatric clinic,...

Objective. Aim of this study were to establish laboratory parameters sideropenic and secondary anemia among children. Methods. From December 1, 2010 January 31, 2011, 35 children with anemia, chronic disease healthy recruited in Hematology infirmary Pediatric Clinic Clinical Centre Kragujevac. All underwent following analyses: count leukocytes (Le), erythrocytes (Er), platelets (Tr), hemoglobin (Hb), hematocrit (Hct), mean corpuscular volume (MCV), (MCH), concentration (MCHC), red blood cell...

Abstract Wandering spleen is a very rare clinical condition characterized by absence in the normal anatomical location upper left quadrant of abdomen and its presence at another or pelvis. The ectopic extremely children, where increased mobility result congenital disturbance fixation for anterior wall due to weakness supporting ligaments. usually asymptomatic, but torsion possible, as well infarction rupture which demand an urgent diagnosis surgical treatment. wandering can easily be...