A5023190821- Autoimmune Bullous Skin Diseases
- Cancer and Skin Lesions
- Drug-Induced Adverse Reactions
- Cutaneous lymphoproliferative disorders research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Autoimmune and Inflammatory Disorders
- Urticaria and Related Conditions
- Chronic Lymphocytic Leukemia Research
- Blood disorders and treatments
- Hedgehog Signaling Pathway Studies
- Systemic Sclerosis and Related Diseases
- Body Contouring and Surgery
- Genetic and rare skin diseases.
- Porphyrin Metabolism and Disorders
- Skin Diseases and Diabetes
- Psoriasis: Treatment and Pathogenesis
- Sympathectomy and Hyperhidrosis Treatments
- Pharmacy and Medical Practices
- Oral and gingival health research
- Eosinophilic Disorders and Syndromes
- Colorectal Cancer Treatments and Studies
- Erythrocyte Function and Pathophysiology
- Heme Oxygenase-1 and Carbon Monoxide
- Inflammatory Myopathies and Dermatomyositis
- IL-33, ST2, and ILC Pathways
Hirosaki University
2012-2023
Aomori Prefectural Central Hospital
2015-2017
Alopecia associated with epidermal growth factor receptor (EGFR) inhibitor therapy is a rare cutaneous side effect the potential to progress scarring alopecia. Thus, dermatologists should make an early diagnosis. We present case of 57-year-old Japanese female alopecia gefitinib, which EGFR inhibitor, including trichoscopic findings. The patient treated gefitinib for non-small cell lung cancer experienced skin rash and hair loss scalp. scalp lesions appeared similar erosive pustular...
Anti-laminin γ1 pemphigoid is a novel autoimmune subepidermal bullous disease characterized by the presence of circulating immunoglobulin (Ig) G autoantibodies to laminin γ1, common constituent at various basement membrane zones (BMZs). Although an association between blistering diseases and inflammatory bowel (IBD) has been reported, there have no previous reports on anti-laminin IBD. Here, we demonstrate case [...]
Abstract Cutis laxa presents as loose redundant skin folds and loss of dermal elastic tissue. Acquired cutis (ACL) is characterized by later onset. It has been reported in association with various kinds neutrophilic dermatoses, drugs, metabolic disorders, autoimmune disorders. Acute generalized exanthematous pustulosis (AGEP) usually classified a severe cutaneous adverse reaction T cell–mediated inflammation. We previously mild case AGEP caused gemcitabine 76‐year‐old man. Here, we report...
Syphilitic alopecia (SA) is a rare skin manifestation in secondary syphilis and sometimes indistinguishable from other alopecia. SA of 2 types, symptomatic essential, 3 clinical moth-eaten or patchy pattern, diffuse pattern combination both. our case indicated with hairloss. A 46-year-old Japanese homosexual man experienced hairloss followed by the pruritic rash. Physical examination scalp showed diffusely spread papulosquamous erythema incomplete around lesions. The lesions appeared as...
We report a case, that is, to our knowledge, the first case of HCQ-induced AGEP in Japan. Our required longer time for complete resolution condition because waxing and waning “smoldering eruption” during clinical course. It is possible unique its course, unlike due other drugs. Acute generalized exanthematous pustulosis (AGEP) rare, but severe cutaneous adverse reaction induced by drugs such as antibiotics, calcium channel blockers, NSAIDs. Hydroxychloroquine sulfate (HCQ), an antimalarial...
We report a 64-year-old female patient with an insulin allergy. She was treated combination of oral antihistamines, topical hydrocortisone cream, and moisturizing agents, which resulted in the improvement eczema intense pruritus. To evaluate allergy, intradermal skin tests were performed several agents for clinical use 0.9% NaCl. Skin testing semisynthetic human local, immediate reactions such as itchy erythema wheals. Furthermore, we analyzed our case 25 Japanese cases allergy previously...
Spitz nevus (SN) is predominantly distributed throughout the lower extremities, while an acral location rare. Since SN occasionally resembles clinicopathological presentation of malignant melanoma (MM), it presents a diagnostic challenge, especially on glabrous skin. Past reports suggest that several genetic aberrations are associated with specific subtypes melanocytic tumors. Immunohistochemistry can provide clue to presence or absence molecular aberration typical We describe case plantar...
We present a case of severe Kaposi's varicelliform eruption in mild atopic dermatitis complicated by rhabdomyolysis. It is rare, but HSV infection AD patients can lead to multiorgan complications. should know that early recognition signs for complications even and prompt administration sufficient amounts antiviral are important clinical practice. Rhabdomyolysis syndrome characterized the disruption striated muscle tissue, may arise from various infections.1 There few reports herpes simplex...