A5031655685- Cancer and Skin Lesions
- Vascular Malformations and Hemangiomas
- Nonmelanoma Skin Cancer Studies
- Cutaneous lymphoproliferative disorders research
- Eosinophilic Disorders and Syndromes
- Tumors and Oncological Cases
- Dermatological and Skeletal Disorders
- Autoimmune Bullous Skin Diseases
- Autoimmune and Inflammatory Disorders
- Urticaria and Related Conditions
- Hedgehog Signaling Pathway Studies
- Genetic and rare skin diseases.
- Skin and Cellular Biology Research
- Nail Diseases and Treatments
- Cutaneous Melanoma Detection and Management
- Viral-associated cancers and disorders
- Systemic Sclerosis and Related Diseases
- Vascular Tumors and Angiosarcomas
- Pituitary Gland Disorders and Treatments
- Herpesvirus Infections and Treatments
- Immunodeficiency and Autoimmune Disorders
- Dermatologic Treatments and Research
- Vascular Malformations Diagnosis and Treatment
- Contact Dermatitis and Allergies
- Melanoma and MAPK Pathways
Hirosaki University
2014-2023
Abstract Impetigo herpetiformis (IH) is a rare variant of generalized pustular psoriasis (GPP), which develops during pregnancy. GPP associated with mutations IL36RN , but it still unclear whether the same true IH. A 20‐year‐old Japanese woman developed erythema and pustules on her trunk 27th week first Within 1 month, skin lesions spread over whole body, accompanied by fever. Skin biopsy revealed Kogoj’s spongiform in epidermis she was diagnosed Systemic administration prednisolone failed...
Drug-induced hypersensitivity syndrome (DiHS) is a severe drug eruption that can induce reactivation of herpesviruses such as human herpesvirus 6, resulting in symptom flare-up and organ damage. DiHS known reaction with eosinophilia systemic symptoms (DRESS) Europe. We report three cases could have been triggered by mRNA-based coronavirus disease 2019 (COVID-19) vaccines. In these patients, developed 2-6 days after the first dose an COVID-19 vaccine. Although there no reports DiHS/DRESS...
Abstract Lichen planus ( LP ) is a chronic inflammatory disorder involving the skin or mucous membranes. Previous studies have demonstrated that some patients showed positive enzyme‐linked immunosorbent assay ELISA for desmoglein DSG antibodies. We report case with intractable painful oral lesions. indices 1 and 3 antibodies were increased by 49 36, respectively. Histopathological analysis revealed irregular acanthosis band‐like infiltration of lymphocytes at dermal–epidermal interface....
Abstract We report a case of dermoid cysts on the right lateral eyebrow and anterior neck. Multiple concurrent cysts, as in present case, are very rare. The differential diagnosis cyst includes epidermoid (epidermal inclusion) cyst, trichilemmal pilomatrixoma, lymphatic malformation, lipoma. In particular, thyroglossal duct midline neck inclusion part when lesion is
Syringomas are benign neoplasms of the eccrine sweat gland ducts that commonly appear around eyelids in women. Clinically, they manifest as small, skin-coloured or slightly pigmented papules. Syringoma is classified into four clinical types: localized; familial; Down’s syn-drome associated; and generalized, which encompasses multiple eruptive syringomas (1). Furthermore, clear cell syringoma, characterized by histological proliferation cells, has been reported to be asso-ciated with diabetes...
The palmoplantar keratodermas (PPKs) are a large group of genodermatoses comprising nearly 60 genetically distinct diseases. They characterized by hyperkeratosis on the palms and soles with or without extrapalmoplantar hyperkeratotic lesions. Focal PPK is one hallmarks pachyonychia congenita, rare autosomal dominant disorder resulting from mutations in keratin genes KRT6A, KRT6B, KRT16 KRT17. Recently, in-frame deletion KRT6C have been identified three families focal slight no nail changes....
Anti-laminin γ1 pemphigoid is a novel autoimmune subepidermal bullous disease characterized by the presence of circulating immunoglobulin (Ig) G autoantibodies to laminin γ1, common constituent at various basement membrane zones (BMZs). Although an association between blistering diseases and inflammatory bowel (IBD) has been reported, there have no previous reports on anti-laminin IBD. Here, we demonstrate case [...]
Primary rhabdoid melanoma (PRM) is a rare variant of melanoma. Herein, we describe case primary amelanotic and review the clinicopathological features previously reported cases PRMs. A 63-year-old Japanese man presented with nonpigmented red granular tumor without peripheral pigmented macules on left heel measuring 21 × 18 mm in size. Light microscopic examination revealed mass composed entirely polygonal neoplastic cells resembling pulmonary alveoli. Tumor were also discohesive bizarre...
Abstract Cutaneous gnathostomiasis ( CG ) is a disease caused by ingestion of third‐stage Gnathostoma larva in raw snakes, freshwater fish or frogs. The common causative organisms Japan include G. nipponicum , spinigerum doloresi binucleatum and hispidum . We report two cases after eating many Japanese icefishes Salangichthys microdon ). In both cases, linear itchy eruptions on the trunk developed S. performed genetic analysis first case, which revealed Of note, this case diagnosed based...
Calcinosis cutis (CC) is a rare disorder known to occur commonly in association with underlying autoimmune connective tissue diseases. CC primarily occurs patients dermatomyositis, systemic scleroderma, and mixed disease. It only rarely associated lupus erythematosus (SLE) even more discoid (DLE).
An 81-year-old Japanese man presented with dark blue papules and nodules on his face. There were multiple soft nodules, in color, compressive, ranging size from 2 to 10 mm. A few similar lesions seen the patient's right dorsal second toe buccal mucosa. no skin trunk upper limbs. The past history did not include gastrointestinal bleeding or anemia. Histopathological examination showed dilated vascular spaces lined by normal epithelium extending beneath dermis into subcutaneous fat. Endoscopy...
A 2-day-old Japanese male infant was referred to our outpatient clinic for multiple cutaneous hemangiomas present since birth. Physical examination revealed 14 small, well-circumscribed red papules, scattered over the head, face, dorsum of right hand, trunk, lower extremities, buttocks and penis. Ultrasound no evidence visceral involvement. Histological a lesion consistent with infantile hemangioma, resulting in final diagnosis benign neonatal hemangiomatosis (BNH). The enlarged by 1 month...
Intratarsal keratinous cyst (IKC) is a benign cystic lesion of the eyelid that retains keratin flakes. IKCs are usually yellow to white lesions but rarely become brown or gray-blue, making clinical diagnosis difficult. The mechanisms by which dark pigments generated in pigmented IKC unclear. authors report case had melanin within lining wall and cyst. Focal infiltrates lymphocytes were observed dermis, particularly beneath areas with more melanocytes intense deposition. These parts faced...