Ujjawal Sharma

ORCID: 0000-0002-2087-080X
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About
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Research Areas
  • RNA Interference and Gene Delivery
  • Parathyroid Disorders and Treatments
  • Alkaline Phosphatase Research Studies
  • Telomeres, Telomerase, and Senescence
  • Renal cell carcinoma treatment
  • Genomics, phytochemicals, and oxidative stress
  • Epigenetics and DNA Methylation
  • Health disparities and outcomes
  • Global Public Health Policies and Epidemiology
  • Climate Change and Health Impacts
  • Nanoparticle-Based Drug Delivery
  • Renal and related cancers
  • Nanoplatforms for cancer theranostics
  • Trace Elements in Health
  • Inflammasome and immune disorders
  • Immunotherapy and Immune Responses
  • Pancreatitis Pathology and Treatment
  • Bioactive natural compounds
  • Computational Drug Discovery Methods
  • Phytochemicals and Medicinal Plants
  • MicroRNA in disease regulation
  • Parvovirus B19 Infection Studies
  • Metal complexes synthesis and properties
  • Obesity, Physical Activity, Diet
  • Phytochemistry and Bioactivity Studies

Central University of Punjab
2022-2025

Maharishi Markandeshwar University, Mullana
2022-2023

University of Central Punjab
2023

Post Graduate Institute of Medical Education and Research
2013-2022

ABES Engineering College
2022

Eternal University
2022

Institute of Post Graduate Medical Education and Research
2020

University of Minnesota
2016

The study introduces an innovative Z‐scheme heterojunction g‐C 3 N 4 /ZnO/PPy (GZP) nanocomposite synthesized through a three‐step process: calcination, coprecipitation, and in situ polymerization of polypyrrole (PPy), with varied PPy concentrations (0.5%, 1%, 2%, 3%, 4%). Extensive characterizations confirmed the successful integration uniform dispersion ZnO on matrix, enhancing surface interaction structural stability. FTIR incorporation , while XRD XPS provided insights into crystalline...

10.1155/jnt/8823568 article EN cc-by Journal of Nanotechnology 2025-01-01

In recent times, there have been notable advancements in comprehending the potential anti-cancer effects of chrysin (CH), a naturally occurring flavonoid compound found abundantly various plant sources like honey, propolis, and certain fruits vegetables. This active has garnered significant attention due to its promising therapeutic qualities minimal toxicity. CH’s ability combat cancer arises from multifaceted mechanisms action, including initiation apoptosis inhibition proliferation,...

10.37349/etat.2024.00230 article EN cc-by Exploration of Targeted Anti-tumor Therapy 2024-05-23

Telomere binding factors viz. TRF1 and TRF2 are a part of sheltrin complex that present exclusively at the ends chromosomes. These play an important role in maintaining chromosomal integrity ends. However, their status not clear renal cell carcinoma (RCC). Therefore, study was conducted to evaluate expressions RCC tissues. Further, these involved tumorigenesis elucidated by gene silencing using siRNA line (A498). The documented significant over-expression (P = 0.005) 0.0048) mRNAs real time...

10.1371/journal.pone.0115651 article EN cc-by PLoS ONE 2015-03-02

One of the mechanisms for epigenetic silencing tumor suppressor genes is hypermethylation cytosine residue at CpG islands their promoter region that contributes to malignant progression tumor. Therefore, activation have been silenced by methylation considered be very attractive molecular target cancer therapy. Epigenetic glutathione S-transferase pi 1, a gene, involved in various types cancers including breast cancer. can reversed several molecules natural compounds such as polyphenols act...

10.1177/1010428317692258 article EN cc-by-nc Tumor Biology 2017-02-01

Abstract Renal cell carcinoma (RCC) is the leading cause among cancer-related deaths due to urological cancers, which results in response combination of genetic and epigenetic factors. Histone methylations have been implicated renal tumorigenesis but their clinical significance underlying pathology are unexplored. Here, we elucidated histone 3 lysine 4 (H3K4) methylation patterns clear RCC its pathology. Lower cellular levels H3K4 mono-methylation, -dimethylation –tri-methylation were...

10.1038/s41598-019-44733-y article EN cc-by Scientific Reports 2019-06-03

Mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene can cause congenital bilateral absence vas deferens. Yet, spectrum and frequency CFTR mutations in Indian males with deferens (CAVD) is unknown.We investigated 50 males, diagnosed unilateral or at PGIMER, Chandigarh, for presence most common as well unknown by single-strand conformation polymorphism followed sequence analysis.This study led to identification 12 on 48% 100 CAVD chromosomes. were identified both...

10.1093/humrep/den500 article EN Human Reproduction 2009-01-31
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