A5047116462- Concrete and Cement Materials Research
- Advanced Photocatalysis Techniques
- Analytical Chemistry and Sensors
- Electrochemical Analysis and Applications
- Genetic factors in colorectal cancer
- Wnt/β-catenin signaling in development and cancer
- X-ray Diffraction in Crystallography
- Lipid Membrane Structure and Behavior
- Agricultural and Food Production Studies
- Crystallization and Solubility Studies
- Reproductive Physiology in Livestock
- Colorectal and Anal Carcinomas
- RNA Interference and Gene Delivery
- Ruminant Nutrition and Digestive Physiology
- Advanced Breast Cancer Therapies
- Advanced Cellulose Research Studies
- Plant pathogens and resistance mechanisms
- Pericarditis and Cardiac Tamponade
- Microwave-Assisted Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Dendrimers and Hyperbranched Polymers
- Metal-Catalyzed Oxygenation Mechanisms
- Cancer-related Molecular Pathways
- Advanced Synthetic Organic Chemistry
- Molecular Sensors and Ion Detection
RMIT University
2023-2024
GEICAM – Spanish Breast Cancer Group
2024
Hospital Universitario Ramón y Cajal
2024
Federico Santa María Technical University
2023
University of Buenos Aires
2023
University of Florida
2018-2021
Pontificia Universidad Católica de Chile
2018-2020
Hospital Luis Calvo Mackenna
2020
Rede de Química e Tecnologia
2018-2020
Centro de Investigación en Materiales Avanzados
2020
Two new coumarin-based “turn-off” fluorescent probes, (E)-3-((3,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS1) and (E)-3-((2,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS2), were synthesized their detection of copper(II) iron(III) ions was studied. Results show that both compounds are highly selective for Cu2+ Fe3+ over other metal ions. However, BS2 is detected directly, while BS1 involves a hydrolysis reaction to regenerate 3-amino-7-hydroxycoumarin (3)...
Replacing anodic oxygen evolution of water splitting or carbon dioxide reduction by electro-organic oxidation increases their product-value and energy efficiency.
mRNA lipid nanoparticle (LNP) technology presents enormous opportunities to prevent and treat various diseases. Here, we developed a novel series of LNPs containing ionizable amino-lipids showing remarkable array tunable pH-sensitive lyotropic liquid crystalline mesophases including the inverse bicontinuous cubic hexagonal phases characterized by high-throughput synchrotron radiation X-ray scattering. Furthermore, with an interest in developing therapeutics for lung macrophage targeting,...
Abstract Macrophages are unique immune cells attracting growing attention as a potential candidate for cell‐based therapy infectious diseases and cancer. Strategies that can reprogramme or gene‐edit macrophages hold across spectrum of acute chronic conditions. Herein, lipid nanoparticles (LNPs) developed containing the ionizable SM‐102, helper monoolein which is known self‐assembly in aqueous solutions into inverse cubic lyotropic liquid crystalline mesophase, cholesterol an mRNA...
Aged and adult populations have differences in the structural, biological, healing properties of skin. Comparative studies under influence retinoids both these are very important and, to best our knowledge, not been performed date. The purpose this study was compare activities topical tretinoin aged animal models wound by secondary intention. Male rats (24 months old, n = 7) (6 8) were used. assigned following groups according dates on which samples excised (day 14 or 21 after model...
Aim: To investigate the relationship between beta-catenin and E-cadherin tissue quantitative expression (content) in tumors clinical prognostic factors patients with left colon cancer. Material Methods: Twenty nine adenocarcinoma located distal to splenic flexure were studied. Diagnosis histological variables related prognosis evaluated using hematoxylin-eosin. Beta-catenin analysed by immunohistochemistry specific anti-beta-catenin anti-E-cadherin monoclonal antibodies. Tissue was...
A Cu(<sc>i</sc>) complex {[Cu<sup>I</sup>(biq)<sub>2</sub>]ClO<sub>4</sub>-biq} with biq = 2,2′-biquinoline was prepared, fully characterized and its properties compared those of the well-known [Cu<sup>I</sup>(biq)<sub>2</sub>]ClO<sub>4</sub> complex.
A set of AuNPs-<sc>l</sc>-TiO<sub>2</sub>NPs nanoaggregates which showed efficient covering the semiconductor's surface by AuNPs, as well suitable AuNP sizes for LSPR-sensibilization were used highly photocatalysts photoinduced HER.
One objective was to evaluate the association of dry matter intake as a percentage body weight (DMI%BW) and energy balance (EB) prepartum postpartum, energy-corrected milk (ECM) postpatum with digestive disorders postpartum. For this, ANOVA used, DMI%BW, EB, ECM were outcome variables, left displaced abomasum (LDA), indigestion, other (ODDZ) explanatory variables. The main DMI%BW EB predictors disorders. logistic regression LDA, ODDZ variables Data from 689 cows 11 experiments compiled. Left...
Deep eutectic solvents (DES) formed using choline chloride (ChCl), p-toluenesulfonic acid (pTSA) of stoichiometry ChCl: pTSA (1:1) and (1:2), its ternary mixtures with phosphoric (PA) 85% as an additive (ChCl: pTSA: PA) were evaluated for cellulose nanocrystal (CNC) isolation. Initially, the hydrolytic efficiency to produce CNC each DES was compared before after adding by Hammett acidity parameters Gutmann acceptor number. Moreover, different molar ratios reaction time studied at 80°C...
The present study aims to identify differences between left and right colon adenocarcinoma arising from identical clonal cell find out if microenvironment has any influence on matrix metalloproteinase-2 (MMP2), p53 β-catenin tumor expressions. Material methods. Rats (RNU) were submitted cecostomy obtain the orthotopic model of (n = 10), while for a diversion distal mucous fistula in descending was used. Cultivated human cells (WiDr) inoculated stomas submucosa. Histopathological analysis,...
Fourth generation polyamidoamine dendrimer (PAMAM, G4) modified with fluorescein units (F) at the periphery and Pt nanoparticles stabilized by L-ascorbate were prepared. These dendrimers hydrophobic used to achieve self-assembling structures, giving rise formation of nanoaggregates in water. The photoactive mainly as photosensitizer process catalytic photoreduction water propitiated light. Complementarily, Pt-ascorbate acted active sites generate H2. Importantly, study functional, optical,...
Both chemotherapy (CT) and endocrine therapy + abemaciclib (ET/ABE) are recommended for high-risk HR+/HER2 early breast cancer (EBC). It is unclear if 12 months (mo.) of ET/ABE could replace CT. We investigate this by comparing their efficacy in neoadyuvant (NAT) setting. CARABELA (NCT04293393) a phase II, randomized, open-label, study mo. ET (letrozole +LHRH analogs premenopausal patients +ABE) vs. 6 CT (standar anthracyclines plus taxanes regimens) as NAT HR+/HER2−, Ki67 ≥20% stage II-III...
A microwave-assisted solid-phase Dötz benzannulation reaction using a resin-bound chromium carbene complex was demonstrated. The cyclization of Wang resin-supported Fischer 1 with various alkynes 2 followed by subsequent treatment cerium(IV) ammonium nitrate (CAN) gave naphthoquinone derivatives 4 in moderate yields without the formation indenes, indenones or cyclobutenones as side products. 1,4-diphenyl butadiyne (R1 = Ph, R2 C≡CPh) cleanly afforded mono product 68% yield any intermolecular...