A5008043697- Enzyme Catalysis and Immobilization
- Carbohydrate Chemistry and Synthesis
- Chemical Synthesis and Analysis
- Immune Response and Inflammation
- Animal Ecology and Behavior Studies
- Pharmacological Effects of Natural Compounds
- Viral Infections and Immunology Research
- Inflammatory mediators and NSAID effects
- SARS-CoV-2 and COVID-19 Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Biochemical Acid Research Studies
- Dermatology and Skin Diseases
- Immune Cell Function and Interaction
- Mosquito-borne diseases and control
- Enzyme Structure and Function
- Hemoglobin structure and function
- Essential Oils and Antimicrobial Activity
- Click Chemistry and Applications
- Animal Behavior and Welfare Studies
- Rabbits: Nutrition, Reproduction, Health
- Electrochemical Analysis and Applications
- Microbial Metabolic Engineering and Bioproduction
- Herbal Medicine Research Studies
- Phytochemistry and Bioactive Compounds
- Biochemical and Structural Characterization
Tesoro (United States)
2023
Phoenix (United States)
2021
Texas A&M University
1985-1987
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA search for peptide ligase: cosolvent-mediated conversion of proteases to esterases irreversible synthesis peptidesCarlos F. Barbas, Jose R. Matos, J. Blair. West, and Chi Huey. WongCite this: Am. Chem. Soc. 1988, 110, 15, 5162–5166Publication Date (Print):July 1, 1988Publication History Published online1 May 2002Published inissue 1 July 1988https://pubs.acs.org/doi/10.1021/ja00223a042https://doi.org/10.1021/ja00223a042research-articleACS...
With continued expansion of the coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome 2 (SARS-CoV-2), both antiviral drugs as well effective vaccines are desperately needed to treat patients at high risk life-threatening disease. Here, we present in vitro evidence for significant inhibition SARS-CoV-2 oleandrin and a defined extract N. oleander (designated PBI-06150). Using Vero cells, found that prophylactic (pre-infection) (as either pure compound or active...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnantioselective oxidation of 1,2-diols to L-.alpha.-hydroxy acids using co-immobilized alcohol and aldehyde dehydrogenases as catalystsChi Huey Wong Jose R. MatosCite this: J. Org. Chem. 1985, 50, 11, 1992–1994Publication Date (Print):May 1, 1985Publication History Published online1 May 2002Published inissue 1 1985https://pubs.acs.org/doi/10.1021/jo00211a046https://doi.org/10.1021/jo00211a046research-articleACS PublicationsRequest reuse...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiphasic one-pot synthesis of two useful and separable compounds using cofactor-requiring enzymatic reactions: glutamate dehydrogenase catalyzed L-.alpha.-aminoadipate coupled with alcohol a chiral lactoneJose R. Matos Chi Huey WongCite this: J. Org. Chem. 1986, 51, 12, 2388–2389Publication Date (Print):June 1, 1986Publication History Published online1 May 2002Published inissue 1 June...
The Nerium oleander extract PBI 05204 (PBI) and its cardiac glycoside constituent oleandrin have direct anti-viral properties. Their effect on the immune system, however, is largely unknown. We used an in vitro model of human peripheral blood mononuclear cells to document effects under three different culture conditions: normal, challenged with viral mimetic polyinosinic:polycytidylic acid Poly I:C, inflamed by lipopolysaccharide (LPS). Cells were evaluated for activation marks CD69, CD25,...
Abstract OBJECTIVE The purpose of the study reported herein was to determine dose oleander extract and oleandrin (the key pharmacologically active constituent) that could be safely administered PO dogs. ANIMALS 42 purebred Beagle dogs were used an Nerium . METHODS 3 studies performed in young adult (ages 12 months or older) using a supercritical fluid N leaves. first 8-day initial dose-ranging 2 dogs, second 7-day repeat-dosing 4 final 32 where test subjects given placebo once daily for 28...
To perform testing for cytokines involved in dermal inflammatory reactions and to document compare the effects of an oleander extract (OE), oleandrin, oclacitinib on biomarkers relevant allergic reactions. The these compounds under inflamed culture conditions are direct importance treatment canine atopic dermatitis.