A5028741097- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Diverticular Disease and Complications
- Music Therapy and Health
- Hidradenitis Suppurativa and Treatments
- Clinical practice guidelines implementation
- Gastrointestinal motility and disorders
- Hernia repair and management
- Dialysis and Renal Disease Management
- Musculoskeletal pain and rehabilitation
- Central Venous Catheters and Hemodialysis
- Surgical site infection prevention
- Pelvic and Acetabular Injuries
- Medical Device Sterilization and Disinfection
- Childhood Cancer Survivors' Quality of Life
- Cancer survivorship and care
- Intraperitoneal and Appendiceal Malignancies
- Stoma care and complications
- Acute Kidney Injury Research
- Colorectal Cancer Screening and Detection
- Testicular diseases and treatments
- Intraoperative Neuromonitoring and Anesthetic Effects
- Enhanced Recovery After Surgery
Regional Hospital Randers
2014-2025
Aarhus University Hospital
2014-2025
Aarhus University
2018-2025
Danish Cancer Society
2018-2022
Aalborg University
2018
University Hospital Heidelberg
2003
Heidelberg University
2003
Boston Children's Hospital
1998
Sahlgrenska University Hospital
1998
<b>BACKGROUND AND PURPOSE:</b> Thromboembolic events are the most common complications of elective coil embolization cerebral aneurysms. Administration oral clopidogrel and/or aspirin could lower thromboembolic complication rate. <b>MATERIALS METHODS:</b> Records over a 10-year period were reviewed in retrospective cohort study. For 369 consecutive procedures, 25 patients received no antiplatelet drugs, 86 drugs only after embolization, and 258 before embolization. <b>RESULTS:</b>...
Abstract Aim Pilonidal sinus disease (PSD) is a common condition particularly affecting young men. Females affected by the account for about 20% of patients and are rarely mentioned, much less studied specifically. In this study we evaluate surgical outcomes in female population following Bascom's cleft lift (BCL) surgery primary extensive disease, non‐healing wounds after previous recurrent large Danish cohort from high‐volume centre. Method The based on prospective database established at...
Aim: The extent of observation bias in long term surgical outcomes due to inadequate or unplanned follow up pilonidal sinus disease (PSD) studies is unclear. We hypothesized a high risk underreported recurrence relying on the patients returning case recurrent (return recurrence; ROR). Methods: 5.485 retrievable PSD publications were screened for eligibility, yielding 1.222 with 133.349 treated, published between 1833 and 2023 included analysis. Of these 139 Randomized Controlled Trials...
Abstract Aim Pilonidal sinus disease (PSD) is a common condition, but no data on occurrence exist outside highly selected settings. The aim of this study was to assess time trends in the incidence PSD nationwide setting. Method Using from Danish registries, we identified 48 247 patients recorded with diagnostic or surgical procedure codes representing between 1996 and 2021. We stratified by sex computed age‐adjusted age‐specific rate, comparing 5‐year intervals rate ratio (IRR). Results...
In May 2010, a specialist nurse-initiated assessment and treatment algorithm for faecal incontinence (FI) was introduced at the department of Anal Physiology, Aarhus University Hospital, Denmark. This study aimed to evaluate effectiveness patient satisfaction with program.A medical file audit preformed on patients evaluated treated FI discharged after September 2010. Patients were invited participate in structured telephone interview. enrol 100 patients. asked if they satisfied their current...
Abstract Aim Pilonidal sinus disease (PSD) is a common condition. Despite relatively large proportion of patients presenting as post‐pubertal adolescents, only small cohorts focusing on this PSD subcategory have been published, and surgical treatment remains challenging. Method The study based prospective database established at Randers Regional Hospital in 2016. All undergoing Bascom's cleft lift (BCL) surgery from June 2016 until 2020 were included study, ≤18 years age comparing them to...
Abstract Background The pathophysiology behind idiopathic fecal incontinence ( IFI ) is poorly understood. We hypothesized abnormal sensory pathways along the brain‐gut axis as a key player in this disease, reflected cortical evoked potentials CEP from mechanical stimuli of rectum and anal canal. Methods s were recorded during repeated rapid balloon distensions canal 19 women with (mean age: 60 ± 14, mean Wexner score: 14.7 2.9) healthy 56 11, 1.1 1.3). Latencies, amplitudes topography...
Abstract Background Sacral nerve stimulation ( SNS ) is a well‐established treatment for fecal incontinence but its mode of action remains obscure. Anal sphincter function usually evaluated with manometry resistance to distension may be more appropriate parameter than luminal pressure. The functional lumen imaging probe allows detailed description properties the anal canal. Our objective in this study was characterize impact on canal patients idiopathic incontinence. Methods We studied 10...
Sphincter-sparing radiotherapy or chemoradiation are standard treatments for patients with anal cancer. The ultimate treatment goal is full recovery from cancer preserved anorectal function. Unfortunately, long-term survivors often suffer severe symptoms. aim of the present study was to characterize changes in physiology after cancer.We included 13 (10 women, age 63.4 ± 1.9) treated and 14 healthy volunteers (9 61.4 1.5). Symptoms were assessed scores fecal incontinence low anterior...
Abstract Background Neurophysiological evaluation of anorectal sensory function is hampered by a paucity methods. Rapid balloon distension ( RBD ) has been introduced to describe the cerebral response rectal distension, but it not successfully applied anal canal. Methods Nineteen healthy women received 30 s in rectum and canal at intensities corresponding unpleasantness thresholds, was recorded as cortical evoked potentials CEP s) 64‐channels. The stimulations level were repeated after 4 min...
It has been suggested that the effects of sacral nerve stimulation against fecal incontinence involve neuromodulation at spinal or supraspinal levels.This study aims to investigate afferent sensory pathways from anorectum before and during stimulation.This is an explorative study.Fifteen women with idiopathic (mean age, 58 ± 12.2 years) were selected.Cortical evoked potentials recorded repeated rapid balloon distension rectum anal canal both temporary stimulation. Stimuli applied...
Abstract Aim Despite favourable outcomes in recurrence after off‐midline closure techniques pilonidal surgery, between 18% and 40% of patients suffer from prolonged postoperative wound healing. The aim this work was to investigate if closed‐incision negative‐pressure therapy (NPWT) promotes healing Bascom's cleft lift (BCL) surgery for complicated sinus disease compared with conventional drainage dressing. Method Patients were randomized either NPWT 4–7 days or loop‐vessel drain 24 h a dry...
Abstract Aim The aim was to study anorectal function in long‐term survivors after combined, curatively intended, chemoradiotherapy and endorectal brachytherapy for low rectal cancer. Methods This a case–control design. We compared by anal manometry, functional lumen imaging probe (EndoFLIP) bag distension cancer patients (RCPs) healthy, normal subjects (NSs). Symptoms were assessed the anterior resection syndrome (LARS) Wexner faecal incontinence scores. Results Thirteen RCPs (12 men, median...
Significant improvements in the treatment of anal cancer have produced a growing population survivors. These patients often experience late adverse effects related to their treatment. Research has revealed substantial unmet needs because long-term symptoms and functional impairments after that may negatively affect health-related quality life. The purpose present guidelines is review scientific evidence for management (chemo)radiotherapy ([C]RT) extrapolate knowledge from other pelvic...
Abstract Background Abnormal central nervous system processing of visceral sensation may be a part the pathogenesis behind idiopathic fecal incontinence ( IFI ). Our aim was to characterize brain differences in patients with and healthy controls by means structural magnetic resonance imaging MRI ) diffusion tensor DTI Methods In 21 female 15 controls, whole‐brain gray matter volume (GMV), cortical thickness, white tracts fractional anisotropy FA were quantified. For this purpose, we used...