A5103002658- Neuroblastoma Research and Treatments
- Pharmacological Receptor Mechanisms and Effects
- Primary Care and Health Outcomes
- Cancer, Hypoxia, and Metabolism
- Healthcare Policy and Management
- Frailty in Older Adults
- Immune cells in cancer
- Hematopoietic Stem Cell Transplantation
- Glioma Diagnosis and Treatment
- Chronic Disease Management Strategies
- Health Systems, Economic Evaluations, Quality of Life
- Hip and Femur Fractures
- Nutrition and Health in Aging
- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Diabetes Treatment and Management
- Radiomics and Machine Learning in Medical Imaging
- Diversity and Career in Medicine
- Cancer therapeutics and mechanisms
- Colorectal Cancer Screening and Detection
- BRCA gene mutations in cancer
- Interpreting and Communication in Healthcare
- Diabetes Management and Research
- Diabetes Management and Education
- Genetic factors in colorectal cancer
University of Chicago
2015-2024
Samsung (South Korea)
2024
Samsung Medical Center
2023-2024
Sungkyunkwan University
2023-2024
Chicago Department of Public Health
2015-2024
University of Chicago Medical Center
2014-2022
University of Illinois Chicago
2014-2020
Frederick S. Pardee RAND Graduate School
2017
San Francisco Department of Public Health
2017
Northwestern University
2017
Key Points GA to guide an MDC evaluation optimize older adult candidates for hematopoietic cellular therapy is feasible and practical. An adults before transplantation holds promise mitigate transplant-related morbidity mortality.
Purpose The purpose of this study was to investigate the behavioral effects a theory-driven, mobile phone–based intervention that combines automated text messaging and remote nursing, using an automated, interactive system. Methods This mixed methods observational cohort study. Study participants were members University Chicago Health Plan (UCHP) who largely reside in working-class, urban African American community. Surveys conducted at baseline, 3 months (mid-intervention), 6...
Abstract Use of allogeneic hematopoietic cell transplantation (alloHCT) is increasing in older patients with hematologic malignancies. Studies suggest that geriatric assessment (GA), incorporating functional measures such as instrumental activities daily living (IADL), delineates subtle age-related impairments enhance risk-stratification. The objective this multi-institutional retrospective study was to evaluate the prognostic utility GA metrics collected pre-alloHCT. Eligibility criteria...
Meticulous postoperative flap monitoring is essential for preventing failure and achieving optimal results in free operations, which physical examination has remained the criterion standard. Despite high reliability of examination, requirement excessive use clinician time been considered a main drawback.
Background To investigate the incidence of second malignant neoplasms (SMN) for patients with neuroblastoma, we analyzed from SEER database according to three treatment eras (Era 1: 1973–1989, Era 2: 1990–1996, and 3: 1997–2006) corresponding introduction multi‐agent chemotherapy, risk‐based treatment, stem cell transplant. Procedures The was mined all neuroblastoma or ganglioneuroblastoma. Cumulative SMN calculated death as a competing risk. A poisson regression model used estimate rate...
<p>Hockey stick plots representing H3K27ac signal strength and enhancer rank to identify super-enhancers in each of the neuroblastoma cell lines.</p>
<h3>Context</h3>Little is known about the cost associated with a health center's rating as patient-centered medical home (PCMH).<h3>Objective</h3>To determine whether PCMH operating among centers funded by US Health Resources and Services Administration.<h3>Design, Setting, Participants</h3>Cross-sectional study of in 2009. was assessed through surveys center administrators conducted Harris Interactive all 1009 Administration–funded community centers. The survey provided scores from 0...
Objective To compare utilization and preventive care receipt among patients of federal Section 330 health centers ( HC s) versus other settings. Data Sources A nationally representative sample adults from the Medical Expenditure Panel Survey (2004–2008). Study Design were defined as those with ≥50 percent outpatient visits at s in first panel year. Outcomes included second We used negative binomial logistic regression models propensity score adjustment for confounding differences between...
Objectives. To compare health care use and spending of Medicaid enrollees seen at federally qualified centers versus non–health center settings in a context significant growth. Methods. Using fee-for-service claims from 13 states 2009, we compared patients receiving the majority their primary with propensity score–matched comparison groups other settings. Results. We found that had lower than did across all services, 22% fewer visits 33% on specialty 25% admissions 27% inpatient care. Total...
Frailty is an important predictor of outcomes after noncardiac surgery. The 5-factor Modified Index (mFI-5) a recently developed frailty metric that has not been adequately evaluated in relation to surgical therapy for lung cancer. We whether the mFI-5 predictive clinical and administrative anatomical resection cancer.Data Society Thoracic Surgeons Database were used evaluate relationship patients undergoing elective cancer from 2015 2018 using logistic regression analyses. Results compared...
The objective of this study was to provider attitudes and perceived barriers the clinical use pharmacogenomics before during participation in an implementation program.From 2012 2017, providers were recruited. After completing semistructured interviews (SSIs) about pharmacogenomics, received training on access a decision support tool housing patient-specific pharmacogenomic results. Thematic analysis SSI conducted (inter-rater reliability κ≥0.75). Providers also completed surveys...
Background. Diabetes guidelines recommend individualizing glycemic goals (A1C) for older patients. The aim of this study was to assess a personalized Web-based decision support tool. Methods. We randomized physicians and their patients with type 2 diabetes (≥65 years age) tool or educational pamphlet (75:25 patients). Prior visit, intervention interacted the tool, which provided risk predictions elicited treatment preferences. Main outcomes included 1) patient-doctor communication, 2)...
Many community health center providers and staff care for Latinos with diabetes, but their Spanish language ability awareness of Latino culture are unknown. We surveyed 512 Midwestern who managed patients diabetes. Few respondents had high (13%) or cultural scores (22%). Of self-reported 76–100% were Latino, 48% moderate/low 49% competency scores. Among these respondents, 3% lacked access to interpreters 27% neither received training nor training. all skills low. Respondents saw a...
In rodent model systems, the sequential changes in lung morphology resulting from hyperoxic injury are well characterized and similar to human acute respiratory distress syndrome. injured lung, alveolar type two (AT2) epithelial cells play a critical role restoring normal structure. Thus characterizing AT2 will provide insights into mechanisms underpinning recovery injury. We applied an unbiased systems-level proteomics approach elucidate molecular contributing repair rat model. were...