A5046277778- Antimicrobial Peptides and Activities
- Plant Stress Responses and Tolerance
- Aquaculture disease management and microbiota
- Insect and Pesticide Research
- Insect and Arachnid Ecology and Behavior
- Genomics and Phylogenetic Studies
- Photosynthetic Processes and Mechanisms
- Biochemical and Structural Characterization
- Essential Oils and Antimicrobial Activity
- Meat and Animal Product Quality
- RNA and protein synthesis mechanisms
- Cellular transport and secretion
- Insect Utilization and Effects
- Bacterial Genetics and Biotechnology
- Plant Molecular Biology Research
- Healthcare and Venom Research
- Microbial Natural Products and Biosynthesis
- Plant nutrient uptake and metabolism
- Aldose Reductase and Taurine
- Plant Reproductive Biology
- Natural product bioactivities and synthesis
- Genetic and phenotypic traits in livestock
- Chromosomal and Genetic Variations
- Plant and animal studies
- Bacteriophages and microbial interactions
National Institute of Biological Resources
2015-2025
Hallym University
2022
Texas A&M University
2013-2020
Sunchon National University
2019
Chungnam National University
2019
Mitchell Institute
2013-2016
College Station Medical Center
2016
Gyeongsang National University
2004-2014
Gyeongnam National University of Science and Technology
2010-2014
Chonnam National University
2004
There are three main dietary groups in mammals: carnivores, omnivores, and herbivores. Currently, there is limited comparative genomics insight into the evolution of specializations mammals. Due to recent advances sequencing technologies, we were able perform in-depth whole genome analyses representatives these groups. We investigated carnivory by comparing 18 representative genomes from across Mammalia with carnivorous, omnivorous, herbivorous specializations, focusing on Felidae (domestic...
Twelve phenolic metabolites (nine ternatin anthocyanins and three glycosylated quercetins) were identified from the blue flowers of Clitoria ternatea by high-performance liquid chromatography diode array detection electrospray ionization/mass spectrometry (HPLC-DAD-ESI/MSn). Three not reported in this species before show fragmentation pattern class. Extracts fractionated fractions containing flavonols (F3) (F4). In general, C. polyphenols showed anti-inflammatory properties...
Transcription and mRNA processing are regulated by phosphorylation dephosphorylation of the C-terminal domain (CTD) RNA polymerase II, which consists tandem repeats a Y 1 S 2 P 3 T 4 5 6 7 heptapeptide. Previous studies showed that members plant CTD phosphatase-like (CPL) protein family differentially regulate osmotic stress-responsive abscisic acid-responsive transcription in Arabidopsis thaliana . Here we report AtCPL1 AtCPL2 specifically dephosphorylate Ser-5 heptad but not Ser-2. An...
In Chl biosynthesis, aerobic Mg-protoporphyrin IX monomethyl ester (MPE) cyclase is a key enzyme involved in the synthesis of protochlorophyllide a, and its membrane-bound component known to be encoded by homologs CHL27 photosynthetic bacteria, green algae plants. Here, we report that Arabidopsis chl27-t knock-down mutant exhibits retarded growth chloroplast developmental defects are caused damage PSII reaction centers. The contains T-DNA insertion within promoter dramatically reduces mRNA...
The Spo0B-associated GTP-binding protein (Obg) GTPase, essential for bacterial viability, is also conserved in eukaryotes, but its primary role eukaryotes remains unknown. Here, our functional characterization of Arabidopsis and rice obgc mutants strongly underlines the evolutionarily eukaryotic Obgs organellar ribosome biogenesis. exhibited a chlorotic phenotype, caused by retarded chloroplast development. A plastid DNA macroarray revealed plastid-encoded RNA polymerase (PEP) deficiency an...
The effects of ultraviolet-C light (UVC) on vitamin C and phenolic compounds in acerola during postharvest storage were investigated order to elucidate the mechanism inducing antioxidant systems. fruits, stored at 10 °C for 7 days after a hormetic UVC irradiation (two pulses 0.3 J/cm2), showed significantly less degradation than control without challenge. activated L-galactono-1,4-lactone dehydrogenase (GalDH), key enzyme biosynthesis, altered composition compounds, through storage. also...
Background: Nibribacter radioresistens, a UV and gamma radiation-tolerant bacterium, was reported to have superior antibacterial activities against variety of pathogenic bacteria through the production antimicrobial peptides (AMPs), but nothing is known about its AMPs. Methods/Results: In this study, our genomic transcriptomic data showed that N. radioresistens genome contains 11 AMP gene candidates, designated as NB_AMP1 NB_AMP11, which are expressed differently in logarithmic growth...
The recent pandemic of coronavirus disease 2019 (COVID-19) has increased demand for chemical disinfectants, which can be potentially hazardous to users. Here, we suggest that the cell-free supernatant from Lactobacillus plantarum NIBR97, including novel bacteriocins, potential as a natural alternative disinfectants. It exhibits significant antibacterial activities against broad range pathogens, and was observed by scanning electron microscopy (SEM) cause cellular lysis through pore formation...
Ellagic acid (EA) is a component of ellagitannins, present in crops such as pecans, walnuts, and many berries, which metabolized by the gut microbiota forms urolithins A, B, C, or D. In this study, ellagic acid, well A were tested on 3T3-L1 preadipocytes for differentiation lipid accumulation. addition, inflammation was studied mature adipocytes challenged with lipopolysaccharide (LPS). Results indicated that EA B did not affect (adipogenesis) only urolithin attenuated accumulation...
Changes in meat quality traits are strongly associated with alterations postmortem metabolism which depend on genetic variations, especially nonsynonymous single nucleotide variations (nsSNVs) having critical effects protein structure and function. To selectively identify metabolism-related nsSNVs, next-generation transcriptome sequencing (RNA-Seq) was carried out using RNAs from porcine liver, contains a diverse range of metabolic enzymes. The multiplex SNV genotyping analysis showed that...
The genomes of free-living bacteria frequently exchange genes via lateral gene transfer (LGT), which has played a major role in bacterial evolution. LGT also significant the acquisition from non-cyanobacterial to lineage 'primary' algae and land plants. Small GTPases are widely distributed among prokaryotes eukaryotes. In this study, we inferred evolutionary history organelle-targeted small Arabidopsis thaliana contains at least one ortholog seven subfamilies OBG-HflX-like...
Seventeen polyphenols (e.g, apigenin, genistein, and luteolin glycosides) 11 lipophilic compounds (e.g., fatty acids, sterols, terpenes) were detected by LC-MS/MS-ESI GC-MS, respectively, in Jatropha platyphylla. Extracts from pulp, kernel, leaves fractions studied to know their effect on some pro-inflammatory mediators. Phenolic extracts showed significant inhibitory effects ROS NO production while not affecting mitochondrial activity or superoxide generation rate lipopolysaccharide...
Arabidopsis thaliana CARBOXYL-TERMINAL DOMAIN (CTD) PHOSPHATASE-LIKE 1 (CPL1) regulates plant transcriptional responses to diverse stress signals. Unlike typical CTD phosphatases, CPL1 contains two double-stranded (ds) RNA binding motifs (dsRBMs) at its C-terminus. Some dsRBMs can bind dsRNA and/or other proteins, but the function of has remained obscure. Here, we report identification REGULATOR OF CBF GENE EXPRESSION 3 (RCF3) as a CPL1-interacting protein. RCF3 co-purified with...
To identify and compare venom components expression patterns, gland-specific transcriptome analyses were conducted for 14 Aculeate bees wasps. TPM (transcripts per kilobase million) values normalized using the average transcription level of a reference housekeeping gene (dimethyladenosine transferase). Orthologous component genes across bee wasp species identified, their relative abundance in each was determined by comparing values. Based on signal sequences transcripts, novel identified...
The prevalence of antibiotic-resistant bacteria has become an immediate threat to public health. Antimicrobial peptides are attracting attention as a new source antibiotics due their ability prevent drug-resistances with fewer side effects. Spider venom is composed various bioactive substances multiple functionalities such antimicrobial and anti-inflammatory Here, RNA sequencing was conducted on the gland spider Pardosa astrigera, potential toxin peptide antibacterial properties selected via...
The goal of this study was to evaluate the influence various supplementary feeds on chemical composition and production bioactive substances in Protaetia brevitarsis larvae. primary feed-oak-fermented sawdust-was supplemented with a variety substances, including aloe, apple, banana, sweet persimmon (S. persimmon) pumpkin pumpkin). Crude protein fat content were highest control S. group, respectively. Supplementary increased unsaturated fatty acids, except group receiving pumpkin, which oleic...
The Ypt/Rab family of small G-proteins is important in regulating vesicular transport. Rabs hydrolyze GTP very slowly on their own and require GTPase-activating proteins (GAPs). Here we report the identification characterization OsGAP1, a Rab-specific rice GAP. OsGAP1 strongly stimulated OsRab8a OsRab11, which are homologs mammalian Rab8 Rab11 that essential for Golgi to plasma membrane (PM) trans-Golgi network (TGN) PM trafficking, respectively. Substitution two invariant arginines within...
Bacteriocins are functionally diverse toxins produced by most microbes and potent antimicrobial peptides (AMPs) for bacterial ghosts as next generation vaccines. Here, we first report that the AMPs secreted from Lactobacillus taiwanensis effectively form of pathogenic bacteria identified bacteriocins, including novel ones. In detail, a cell-free supernatant L. exhibited activities against was observed to cause cellular lysis through pore formation in membrane using scanning electron...
Pig aldo-keto reductase family 1 member C1 (AKR1C1) belongs to AKR superfamily which catalyzes the NAD(P)H-dependent reduction of various substrates including steroid hormones. Previously we have reported two paralogous pig AKR1C1s, wild-type AKR1C1 (C-type) and C-terminal-truncated (T-type). Also, C-terminal region significantly contributes NADPH-dependent activity for 5α-DHT reduction. Molecular modeling studies combined with kinetic experiments were performed investigate structural...