- Yersinia bacterium, plague, ectoparasites research
- Bacillus and Francisella bacterial research
- Bacteriophages and microbial interactions
- Vector-borne infectious diseases
- Vibrio bacteria research studies
- Pharmacological Effects of Natural Compounds
- Zoonotic diseases and public health
- Force Microscopy Techniques and Applications
- Escherichia coli research studies
- Plant-based Medicinal Research
- Microbial infections and disease research
- Mycobacterium research and diagnosis
- Mechanical and Optical Resonators
- Bacterial biofilms and quorum sensing
- Lipid Membrane Structure and Behavior
Vyatka State University
2015-2024
Institute of Biology of Komi Scientific Centre
2014-2024
Czech Academy of Sciences, Institute of Physiology
2019-2023
Russian Academy of Sciences
2016-2023
Ural Branch of the Russian Academy of Sciences
2023
Objective was to assess the effect of specific bacteriophages and gentamycine on morphological-functional properties bacteria in vaccine strain Yersinia pestis EV. Materials methods . The Y. EV, Pokrovskaya bacteriophage pseudotuberculous diagnostic were used for study. microbial culture grown solid liquid growth media at 27 °C 20–24 h. co-incubation or carried out 20 minutes 37 2 hours, respectively. Culture preparations examined by transmission electron microscopy. Results discussion...
Carried out has been electron-microscopic investigation of dynamics interactions between Yersinia pseudotuberculosis, pestis cells and specific bacteriophages in vitro. Identified have peculiarities morphological manifestation the interactions. Determined are morphometric characteristics utilized experiment. It is demonstrated that after 40 minutes co-incubation Y. pseudotuberculosis with bacteriophage emergence persisting forms microbial observed, while case EV strain infecting Pokrovskaya...
Aim. Study of mechanism reception plague bacteriophage Pokrovsky to cells Yersinia pestis using a panel monoclonal antibodies. Materials and methods. Using method competitive inhibition, the ability antibodies against antigenic epitopes outer membrane genus bacteria inhibit adhesion studied Y. EV strain, was evaluated. Results. A key role structure carbohydrate nature in confirmed. Among 5 lines protein 2 were established cause significant inactivation bacterial cells. Conclusion. An...
In recent years, there has been increasing interest in using bacteriophages the complex therapy of some infectious diseases. Objectively, it is related to spread antibiotic resistance and a small number side effects triggered by phages applied locally parenterally. Yersiniae are no exception this rule, but their interaction with virions not studied thoroughly. three types lytic used for diagnostic purposes, which differ specificity, virulence, morphological features. We evaluated force...