- Sexual function and dysfunction studies
- Genital Health and Disease
- Reconstructive Surgery and Microvascular Techniques
- Urological Disorders and Treatments
- Urologic and reproductive health conditions
- LGBTQ Health, Identity, and Policy
- Sexuality, Behavior, and Technology
- Sexual Differentiation and Disorders
- Female Genital Mutilation/Cutting Issues
- Liver Disease Diagnosis and Treatment
- Hormonal and reproductive studies
- Gallbladder and Bile Duct Disorders
- Hepatitis C virus research
- Cardiac Imaging and Diagnostics
- Genetics, Bioinformatics, and Biomedical Research
- Hepatitis B Virus Studies
- Diverse Educational Innovations Studies
- Advancements in Photolithography Techniques
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Hydraulic Fracturing and Reservoir Analysis
- Berry genetics and cultivation research
- Reproductive Health and Technologies
- Liver Disease and Transplantation
- Pelvic and Acetabular Injuries
University College London
2020-2025
University College Hospital
2020-2025
Spire Little Aston Hospital
2025
University College London Hospitals NHS Foundation Trust
2022-2025
King Edward VII Hospital
2025
St Peter's Hospital
2022-2024
St Bartholomew's Hospital
2024
The Royal Free Hospital
2024
New Mexico Institute of Mining and Technology
2023
Barwon Health
2022
To extend earlier observations of germline E-cadherin mutations in kindreds with an inherited susceptibility to diffuse gastric cancer, we searched for five further families affected predominantly by cancer and one family a history early-onset breast cancer. Heterozygous inactivating were found the gene each these families. No mutation hotspots identified. These results demonstrate that is common cause hereditary suggest role incidence Hum Mutat 14:249–255, 1999. © 1999 Wiley-Liss, Inc.
The aim of this study was to reveal nationwide seroprevalence HCV infection in South Korea by a large-scale survey.From January December 2009, total 291 314 adults underwent health check-up 29 centres nationwide. data concerning anti-HCV antibody and biochemical tests were obtained from all participants. Among subjects with positive anti-HCV, such as RNA, genotypes treatment detail additionally analysed.Using an estimated 2009 population Korea, the age, sex area-adjusted rate 0.78%. Anti-HCV...
Abstract This paper continues the investigation of interwell fracturing interference for an infill drilling scenario synthetic case based on Eagle Ford available public data and explores pressure stress-sink mitigation strategies applied to simulation cases developed in previous publication (SPE 174902). Emphasis is given refracturing scenarios, intrinsic restimulation value depleted parent wells strategic importance due current low oil prices. The stress depletion methodology expanded this...
Abstract Background and Aim: Obesity as a risk factor for colorectal neoplasm (CRN) is controversial. In the present study, we evaluated visceral obesity CRN. Methods: We prospectively enrolled 200 consecutive, asymptomatic adults (male : female = 133:67, mean age, 50.9 ± 8.5 years) undergoing both colonoscopy abdominopelvic computed tomography (CT) scan routine health evaluations. The presence or absence characteristics of CRN were determined during colonoscopy. amount adipose tissue (VAT)...
<b>Background and study aims:</b> Endoscopic retrograde cholangiopancreatography (ERCP)-related duodenal perforation is rare but can cause high mortality. Our aim was to assess the clinical outcomes of these events. <b>Method: </b>A total 59 patients who were diagnosed as having ERCP-related at six institutions between 2000 2007 enrolled in this multicenter retrospective study. We evaluated complications mortality associated with according injury detection time (IDT), peritoneal irritation...
Objectives To determine if portable video media (PVM) improves patient's knowledge and satisfaction acquired during the consent process for cystoscopy insertion of a ureteric stent compared to standard verbal communication (SVC), as informed is crucial component patient care PVM an emerging technology that may help improve process. Patients Methods In this multi‐centre randomised controlled crossover trial, patients requiring were recruited from two major teaching hospitals in Australia over...
Although the incidence of colorectal cancer is rising in Asian countries, there are no guidelines for its screening this region due part to lack epidemiological data regarding neoplasms. This study aimed evaluate prevalence neoplasms average-risk Koreans and assess effectiveness colonoscopy Korea.The was assessed by primary 5,086 consecutive asymptomatic adults (males 70.5%; age 20-84 years) with risk factors cancer.The overall subjects 21.9% increased linearly age. Among 2,435 aged >or=50...
We have investigated the ability of intracellular vitamin C to protect human umbilical vein endothelial cells from exposure hypochlorous acid (HOCl) and a range derived chloramines. Ascorbate provided minimal protection against cytotoxicity induced by these oxidants, as measured propidium iodide uptake. In contrast, there was marked effect on apoptosis, monitored caspase-3 activation phosphatidylserine exposure. Extended incubation with glycine chloramine or histamine completely blocked...
<i>Objectives:</i> The study was aimed to investigate the relationship between plasma transforming growth factor beta 1 (TGF-β<sub>1</sub>) expression and characteristics of hepatocellular carcinoma (HCC). <i>Methods:</i> Five hundred seventy-one patients with HCC were subjected. Plasma TGF-β<sub>1</sub> levels measured by enzyme-linked immunosorbent assay at diagnosis compared in accordance clinical radiological characteristics....
Abstract Hepatitis B virus (HBV) infection is the major cause of chronic liver disease in Korea. This study investigated seroprevalence HBV with an emphasis on coexistence hepatitis surface antigen (HBsAg) and antibody (anti‐HBs). In all, 290,212 people undergoing health check‐up examinations 29 institutions during 2009 were recruited. The crude seroprevalences HBsAg anti‐HBs was adjusted by age, sex, geographic area using estimated population 4.0% 73.5%, respectively. Males showed higher...
In this study, we analyzed the rates and patterns of recurrences in hepatocellular carcinoma (HCC) patients who had achieved complete remission (CR) by transarterial chemoembolization (TACE) or radiofrequency ablation (RFA), also examined differences recurrence between TACE-treated RFA-treated groups.We followed 309 consecutive HCC CR following TACE (n = 220) RFA 89) for a median 68 months. Recurrence were classified as local secondary tumor according to location (≤2 cm >2 from primary...
Abstract Background Endoscopic papillary large balloon dilation (EPLBD) without prior endoscopic sphincterotomy (EST) produces excellent outcomes for the treatment of common bile duct (CBD) stones. However, it remains unclear how EPLBD alone compare with those EST. In this study, we assessed safety and therapeutic vs. EST removal Methods This prospective, multicenter study was conducted on 200 patients stones ≥ 10 mm in diameter. Patients were randomly assigned to an group (n = 100) or 100)....
Background/Aims: Although endoscopic ultrasound guided fine needle aspiration (EUS-FNA) has been introduced and its use increasing in Korea, there have not many reports about performance.The aim of this study was to assess the utility EUS-FNA without on-site cytopathologist establishing diagnosis solid pancreatic peripancreatic masses from a single institution Korea.Methods: Medical records 139 patients who underwent for mass year 2007, were retrospectively reviewed.By comparing...
A man aged 30 years presented to an emergency department with a 1 month history of severe abdominal pain, jaundice, constipation, lower extremity weakness and weight loss. peripheral blood smear was performed that showed basophilic stippling erythrocytes prompting lead level (BLL) evaluation. The patient had BLL >200 µg/dL. Retained bullet fragments were identified in the left from previous gunshot wound 10 prior. Lead excised fragment consistent patient's by isotope ratio analysis. This...