A5071506373- Birth, Development, and Health
- Mercury impact and mitigation studies
- Fatty Acid Research and Health
- Vitamin D Research Studies
- Thyroid Disorders and Treatments
- Nutritional Studies and Diet
- Air Quality and Health Impacts
- Heavy Metal Exposure and Toxicity
- Selenium in Biological Systems
- Gestational Diabetes Research and Management
- Neonatal Health and Biochemistry
- Child Nutrition and Water Access
- Reproductive System and Pregnancy
- Neuroscience of respiration and sleep
- Folate and B Vitamins Research
- Obesity, Physical Activity, Diet
- Per- and polyfluoroalkyl substances research
- Marine animal studies overview
- COVID-19 Impact on Reproduction
- Diet and metabolism studies
- Iron Metabolism and Disorders
- Breastfeeding Practices and Influences
- Vitamin C and Antioxidants Research
- Autism Spectrum Disorder Research
- Pregnancy and Medication Impact
University of Ulster
2016-2025
Food for Health Ireland
2013-2025
University of Rochester
2012-2020
Ministry of Health
2012-2015
Monash University
2012
Background: Mercury is a neurotoxin, and limited prenatal exposure to it can affect long-term child neurodevelopment. However, results of epidemiologic studies such have been inconsistent. We examined the association mercury from maternal fish consumption with neurodevelopment in northern Italy.Methods: A population-based cohort 606 children their mothers was studied pregnancy age 18 months. levels were measured hair blood during umbilical cord breast milk. Levels polyunsaturated fatty acids...
Adequate I intake is important before conception and during pregnancy for optimal infant neurodevelopment. Recent studies have highlighted the prevalence of deficiency in UK Ireland. It possible that may be impeded by a poor knowledge nutrition. This study aimed to investigate among women childbearing age Ireland determine whether relationship exists between dietary intake. Females (aged 18-45 years) were invited complete an online questionnaire, which assessed estimated using FFQ. A total...
Abstract Background Studies investigating associations between prenatal polyunsaturated fatty acid status (PUFAs), in particular the anti‐inflammatory n‐3 PUFAs, and development of childhood asthma have yielded conflicting results. Objective To determine maternal fish intake (a rich source PUFAs), or cord PUFAs with prevalence a high fish‐eating population. Methods We examined these PUFA concentrations Seychelles Child Development Study Nutrition Cohort 2, large observational study Maternal...
Telomere length (TL) and mitochondrial DNA copy number (mtDNAcn) variations are linked to age-related diseases associated with environmental exposure nutritional status. Limited data, however, exist on the associations mercury exposure, particularly early in life.
Vitamin D insufficiency is common among the adolescent population and may have implications for health outcomes in later life. Few studies investigated role of vitamin status muscle function cardiorespiratory fitness (CRF) during adolescence. The aim this study was to investigate association between fat-free mass (FFM), strength, power, CRF a representative sample adolescents from Northern Ireland. This cross-sectional involving 1015 (age 12 15 y), who had 25-hydroxyvitamin [25(OH)D] data...
Cow’s milk is the most important dietary source of iodine in UK and Ireland, also contributes to selenium intakes. The aim this study was investigate effect season, fat class (whole; semi-skimmed; skimmed) pasteurisation on concentrations Northern Ireland (NI) milk, estimate contribution consumer Milk samples (unpasteurised, whole, semi-skimmed were collected weekly from two large NI creameries between May 2013 April 2014 analysed by inductively coupled plasma-mass spectrometry (ICP-MS)....
Glutathione (GSH) pathways play a key role the metabolism and elimination of neurotoxicant methylmercury (MeHg). We hypothesized that maternal genetic variation linked to GSH could influence MeHg concentrations in pregnant mothers children thereby also affect early life development.The GCLM (rs41303970, C/T), GCLC (rs761142, T/G) GSTP1 (rs1695, A/G) polymorphisms were genotyped 1449 prospective study Seychellois population with diet rich fish. Genotypes analyzed association hair blood Hg,...
ATP-binding cassette (ABC) transporters have been associated with methylmercury (MeHg) toxicity in experimental animal models. To evaluate the association of single nucleotide polymorphisms (SNPs) maternal ABC transporter genes 1) hair MeHg concentrations during pregnancy and 2) child neurodevelopmental outcomes. Nutrition Cohort 2 (NC2) is an observational mother-child cohort recruited Republic Seychelles from 2008–2011. Total mercury (Hg) was measured growing as a biomarker for prenatal...
Vitamin D has an important role in early life; however, the optimal vitamin status during pregnancy is currently unclear. There have been recent calls for pregnant women to maintain circulating 25-hydroxyvitamin (25(OH)D) concentrations >100 nmol/L health, yet little known about long-term potential benefits or safety of achieving such high maternal 25(OH)D infant child health outcomes. We examined and its associations with anthropometric later childhood neurocognitive outcomes a...
Fish is a primary source of protein and n-3 PUFA but also contains methylmercury (MeHg), naturally occurring neurotoxicant to which, at sufficient exposure levels, the developing fetal brain particularly sensitive. To examine association between prenatal MeHg maternal status n-6 with neurodevelopment, determine whether might modify associations neurodevelopment. We examined Seychelles Child Development Study Nutrition Cohort 2 (NC2) age 7 y. used sophisticated extensive neurodevelopmental...
Choline is an essential nutrient that found in many food sources and plays a critical role the development of central nervous system. Animal studies have shown choline status pre- postnatally can long-lasting effects on attention memory; however, human subjects not been well studied. The aim present study was to examine association between plasma concentrations free its related metabolites children their neurodevelopment Seychelles Child Development Nutrition Study, ongoing longitudinal...
Abstract Background Dietary sources of vitamin D (both natural and fortified) are increasingly contributing to consumers’ intake status. Therefore, the present study aimed validate a food frequency questionnaire ( FFQ ) for assessment habitual intake. Methods A total 49 apparently healthy consenting adults (aged 18–64 years) from local community were sampled at end winter. intakes recorded using 4‐day weighed record (4d‐ WFR 17‐item based on foods known contribute dietary Fasting status was...
Vitamin D status is associated with muscle strength and quality of life in patients COPD: a seasonal prospective observation study Emma L Carson,1 Kirsty Pourshahidi,1 Sharon M Madigan,2 Francina R Baldrick,1 Martin G Kelly,3 Eamon Laird,4 Healy,5 JJ Strain,1 Maria S Mulhern1 1Nutrition Innovation Centre for Food Health (NICHE), School Biomedical Sciences, University Ulster, Coleraine, Co. Londonderry, UK; 2Respiratory Dietitian, Pulmonary Rehabilitation Team, Belfast Social Care Trust,...