A5039912614- biodegradable polymer synthesis and properties
- Advanced Drug Delivery Systems
- RNA Interference and Gene Delivery
- Nanoparticle-Based Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Advanced Polymer Synthesis and Characterization
- Hydrogels: synthesis, properties, applications
- Antimicrobial agents and applications
- Drug Solubulity and Delivery Systems
- Synthesis and properties of polymers
- Advanced biosensing and bioanalysis techniques
- Virus-based gene therapy research
- Biopolymer Synthesis and Applications
- Polymer Surface Interaction Studies
- Advancements in Transdermal Drug Delivery
- Carbon dioxide utilization in catalysis
- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Surgical Sutures and Adhesives
- Ocular Surface and Contact Lens
- Lipid Membrane Structure and Behavior
- Dendrimers and Hyperbranched Polymers
- 3D Printing in Biomedical Research
- Coronary Interventions and Diagnostics
- Orthopaedic implants and arthroplasty
American Hip Institute
2025
Hebrew University of Jerusalem
2015-2024
Komatsu (Japan)
2023
Hadassah Medical Center
2002-2022
Ministry of Social Affairs and Social Services
2020
Azrieli College of Engineering Jerusalem
2014-2017
ORT Israel
2016
Government Medical College
2015
Helmholtz-Zentrum Hereon
2014
Hebrew College
2013
It has been found that, dependent on the crystallization temperature (Tc), disorder (α') and order (α) phases of poly(l-lactide) (PLLA) are formed at low (Tc < 100 °C) high ≥ 120 temperatures, respectively. In DSC curves, sample with α' phase demonstrates a peculiar small exothermal peak around 160 °C just prior to melting point, while crystallized temperatures (between 110 130 shows double behavior. These distinct thermal behaviors various PLLA samples were investigated in detail by...
Poly(l-lactide) (PLLA) and poly(d-lactide) (PDLA) crystallize into a stereocomplex with melting point 50 °C higher than the crystals of enantiomers. The racemic crystal is formed by packing β-form 31-helices opposite absolute configuration alternatingly side side. Single exhibit triangular shape. drastic difference powder patterns evidences different in pure lactides. By force field simulation PLLA unit cells their patterns, reasons for could be clarified. Between β-helices stereocomplex,...
The revelation of biodegradable polymers dates back to many years ago. From then, their emergence leads the surge biomaterials applicable in various fields like controlled drug delivery, regenerative medicine, orthopedic and long‐term implants which proved out be momentous contributions these materials. immense effort investigation kept on materials are reflected by significant upsurge polymer‐based marketed products ongoing clinical trials synthetic versatility flexible features get custom...
// Talia Golan 1 , Elina Zorde Khvalevsky 2 Ayala Hubert 3 Rachel Malka Gabai Naama Hen Amiel Segal 4 Abraham Domb 5 Gil Harari 6 Eliel Ben David 7 Stephen Raskin Yuri Goldes Eran Goldin 8 Rami Eliakim Maor Lahav Yael Kopleman 9 Alain Dancour Amotz Shemi and Eithan Galun 10 The Sackler School of Medicine, Chaim Sheba Medical Center, Tel Aviv University, Aviv, Israel Silenseed Ltd., Jerusalem, Sharett Institute Oncology, Hadassah-Hebrew University Gastroenterology Institute, Shaare Zedek...
Pancreatic ductal adenocarcinoma (PDA) represents an unmet therapeutic challenge. PDA is addicted to the activity of mutated KRAS oncogene which considered so far undruggable target. We propose approach target effectively in patients using RNA interference. To meet this challenge, we have developed a local prolonged siRNA delivery system (Local Drug EluteR, LODER) shedding against (siG12D LODER). The siG12D LODER was assessed for its structural, release, and properties vitro vivo. effect on...
Polylactic acid (PLA) is a biodegradable, biocompatible, non-toxic and eco-friendly polymer. PLA its composites are currently used in medical implants, tissue engineering, orthopedic devices, drug delivery systems, etc. The present review highlights recent research patents for the utility of based polymers their blends biomedical applications. Keywords: Biomedical applications, PLA.
Secondary metabolites, polyphenols, are widespread in the entire kingdom of plants. They contain one or more hydroxyl groups that have a variety biological functions natural environment. These uses include polyphenols food, beauty products, dietary supplements, and medicinal products grown rapidly during past 20 years. Antimicrobial described together with their sources, classes, subclasses. Polyphenols found different such as dark chocolate, olive oil, red wine, almonds, cashews, walnuts,...