A5007308825- Advanced Topology and Set Theory
- Computability, Logic, AI Algorithms
- Mathematical and Theoretical Analysis
- Advanced Algebra and Logic
- Food Allergy and Anaphylaxis Research
- Virus-based gene therapy research
- Graph Labeling and Dimension Problems
- Logic, programming, and type systems
- Autoimmune Bullous Skin Diseases
- Advanced Database Systems and Queries
- Allergic Rhinitis and Sensitization
- Logic, Reasoning, and Knowledge
- Cardiovascular Function and Risk Factors
- Biochemical Analysis and Sensing Techniques
- Epigenetics and DNA Methylation
- Constraint Satisfaction and Optimization
- Facial Trauma and Fracture Management
- Systemic Sclerosis and Related Diseases
- Immunotherapy and Immune Responses
- Orthopedic Infections and Treatments
- Advanced Mathematical Theories
- Dermatology and Skin Diseases
- Bone Metabolism and Diseases
- Biomarkers in Disease Mechanisms
- Immune Response and Inflammation
Freie Universität Berlin
2020-2024
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2024
Berlin-Brandenburger Centrum für Regenerative Therapien
2024
Charité - Universitätsmedizin Berlin
2020-2022
Humboldt-Universität zu Berlin
2020
University of Bonn
2007-2016
Zimmer Biomet (Germany)
2015-2016
Institut für Medizinische Biometrie, Informatik und Epidemiologie
2015
University Hospital Bonn
2015
University of Amsterdam
2005
Atopic dermatitis (AD) starts most often during the first years of life and goes into remission in a high proportion cases childhood. However, severe cases, AD persists until adulthood or relapses later life. So far, studies investigating natural course adolescence are rare. The aim our study was to classify different courses correlate these with specific risk factors for variants AD. A detailed clinical examination retrospective evaluation history disease were performed collective 725...
Abstract Beyond SARS‐CoV2 vaccines, mRNA drugs are being explored to overcome today's greatest healthcare burdens, including cancer and cardiovascular disease. Synthetic triggers immune responses in transfected cells, which can be reduced by chemically modified nucleotides. However, the side effects of mRNA‐triggered activation on cell function how different nucleotides, such as N1‐methylpseudouridine (m1Ψ) used modulate cellular is not fully understood. Here, toward a library...
The melanocortin 4 receptor (MC4R) is a key player in hypothalamic weight regulation and energy expenditure as part of the leptin–melanocortin pathway. Mutations this G protein coupled (GPCR) are most common cause for monogenetic obesity, which appears to be mediated by changes anorectic action MC4R via GS-dependent cyclic adenosine-monophosphate (cAMP) signaling well other pathways. To study potential bias effects mutations between different pathways, we investigated three major mutations:...
This paper is about a special version of PDL, proposed by Marcus Kracht, for reasoning sibling ordered trees. It has four basic programs corresponding to the child, parent, left- and right-sibling relations in such The original motivation this language rooted field model-theoretic syntax. Motivated recent developments area semi-structured data, and, especially, query languages XML (eXtensible Markup Language) documents, we revisit language. renewed interest comes with focus on complexity...
Hypomethylation of long interspersed element (LINE)-1 has been observed in tumorigenesis when using degenerate assays, which provide an average across all repeats. However, it is unknown whether individual LINE-1 loci or different CpGs within one specific promoter are equally affected by methylation changes. Conceivably, studying changes at may be more informative than global assays for cancer diagnostics. Therefore, with the aim mapping single-CpG resolution and exploring diagnostic...
OBJECTIVE: To evaluate the safety and efficacy of recombinant gamma interferon (rIFN gamma) in treatment patients with systemic sclerosis. METHODS: Sixteen sclerosis were treated r-IFN gamma, 60 micrograms m-2 (low dose, n = 10) 150 (high 6), three times weekly an open phase I/II trial eight months duration. The stratified low high dose according to severity extent scleroderma; two groups comparable. RESULTS: was well tolerated. most common side effects, almost certainly related fever,...
The role of CD64 in late onset sepsis (LOS) preterm infants has been described several studies. Aim this study was to investigate whether expression is increased the days before clinical manifestation LOS.Patients with birth weight below 1,500 g were eligible for participation. During routine blood sampling index determined between day life 4 and 28. Patients allocated one four groups: (1) blood-culture positive sepsis, (2) (3) symptoms infection without biochemical evidence infection, or...
Social behavior of honeybees (Apis mellifera) has been extensively investigated, but little is known about its neuronal correlates. We developed a method that allowed us to record extracellularly from mushroom body extrinsic neurons (MB ENs) in freely moving bee within small functioning mini colony approximately 1000 bees. The aim this study was correlate activity multimodal high-order MB ENs with social close natural setting. all bees the video recorded. recorded animal compared other hive...
To assess the time intervals of cardiac cycle in healthy fetuses second and third trimester using color tissue Doppler imaging (cTDI) to evaluate influence different sizes sample gates on interval values.Time were measured from cTDI-derived waveform a small large region interest (ROI) fetuses.40 included. The median gestational age at examination was 26 + 1 (range: 20 5 - 34 5) weeks. frame rate 116/s (100 161/s) heart 143 125 158) beats per minute (bpm). Using ROIs, right ventricular (RV)...
We use techniques due to Moti Gitik construct models in which for an arbitrary ordinal ϱ, is both the least measurable and regular uncountable cardinal.
We consider four notions of strong inaccessibility that are equivalent in $\mathsf {ZFC}$ and show they not $\mathsf{ZF}$.
Introduction Open reduction and fixation are the standard of care for treating mandibular fractures usually lead to successful healing. However, complications such as delayed healing, non-union, infection can compromise patient outcomes increase healthcare costs. The initial inflammatory response, particularly response involving specific CD8 + T cell subpopulations, is thought play a critical role in healing long bone fractures. In this study, we investigated these immune profiles patients...
Using the analysis developed in our earlier paper , we show that every uncountable cardinal Gitik's model of which all cardinals are singular is almost Ramsey and also a Rowbottom carrying filter. We assume constructed from proper class strongly compact cardinals, each limit measurable cardinals. Our work consequently reduces best previously known upper bound consistency strength for theory + “All singular” “Every both filter”.