Mengke Sun

ORCID: 0000-0002-2305-2693
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Polysaccharides and Plant Cell Walls
  • Seaweed-derived Bioactive Compounds
  • Skin Protection and Aging
  • Contact Dermatitis and Allergies
  • Dermatology and Skin Diseases
  • Fungal Biology and Applications
  • Pharmacological Effects of Natural Compounds
  • Nanoparticles: synthesis and applications
  • Human Health and Disease
  • Pituitary Gland Disorders and Treatments
  • Invertebrate Immune Response Mechanisms
  • Graphene and Nanomaterials Applications
  • Plant Molecular Biology Research
  • Advanced Drug Delivery Systems
  • TGF-β signaling in diseases
  • Aluminum toxicity and tolerance in plants and animals
  • Aquaculture disease management and microbiota
  • Plant Stress Responses and Tolerance
  • Genomics, phytochemicals, and oxidative stress
  • Insect-Plant Interactions and Control
  • Plant Parasitism and Resistance
  • Simulation-Based Education in Healthcare
  • Psoriasis: Treatment and Pathogenesis
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology

Sichuan Agricultural University
2024

Fujian Agriculture and Forestry University
2021-2024

Xinyang Normal University
2022-2023

Tianjin Medical University
2020-2022

Qingdao University
2021

Institute of Computing Technology
2021

Chinese Academy of Sciences
2021

Background There are no established accurate models that use machine learning (ML) methods to preoperatively predict immediate remission after transsphenoidal surgery (TSS) in patients diagnosed with histology-positive Cushing’s disease (CD). Purpose Our current study aims devise and assess an ML-based model TSS CD. Methods A total of 1,045 participants CD who received at Peking Union Medical College Hospital a 20-year period (between February 2000 September 2019) were enrolled the present...

10.3389/fendo.2021.635795 article EN cc-by Frontiers in Endocrinology 2021-03-02

Abstract NF-erythroid 2–related factor 2 (Nrf2) is a major transcription to protect cells against reactive oxygen species (ROS) and toxicants. Meanwhile, Nrf2 can inhibit contact dermatitis through redox-dependent -independent pathways. However, the underlying mechanisms of how mediates irritant (ICD) are still unclear. In this article, we elucidated role in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced acute ICD. Our study demonstrated that ear thickness, redness, swelling, neutrophil...

10.4049/jimmunol.2100577 article EN The Journal of Immunology 2022-02-23

Tea plants are continuously confronted with a wide range of biotic and abiotic stressors in the field, which can occur concurrently or sequentially. To elucidate molecular mechanisms responses to such individual combined stresses, we used RNAseq compare temporal changes transcriptome Camellia sinensis Ectropis oblique Prout alone combination exposure drought heat. Compared stress, tea exhibit significant differences profiles under stresses. Additionally, many unique genes exhibited...

10.1016/j.ygeno.2022.110506 article EN cc-by Genomics 2022-10-18

The benefits of emollients for eczematous dermatitis and psoriasis have been thought to be due the improvements in epidermal function, including permeability barrier, stratum corneum hydration, pH. We determined here whether emollient can direct inhibit cutaneous inflammation. Ear inflammation was induced by topical application either 12-O-tetradecanoylphorbol-13-acetate (TPA) or 1-fluoro-2,4-dinitrofluorobenzene (DNFB). Either 1% hydrocortisone cream novel applied right ear mice 45 min 2...

10.1155/2021/5594646 article EN cc-by BioMed Research International 2021-04-13

Disruption of epidermal barrier is an important trigger in abnormal cutaneous inflammation. Phospholipase C epsilon (PLCε), a Ras/Rap1 effector, essential for regulating cytokines production different types skin Our previous studies have demonstrated that elevated expression PLCε participates the psoriasis-like inflammation overexpressing transgenic mice model, while reduction attenuates inflammatory responses either TPA- or DNFB-induced Here, we determined role induced by acute abrogation...

10.1016/j.bbrep.2020.100869 article EN cc-by-nc-nd Biochemistry and Biophysics Reports 2020-12-01

Objective: To investigate the clinical effect and safety of rock salt aerosol therapy in treatment occupational allergic contact dermatitis. Methods: A total 65 patients with acute exacerbation dermatitis who were treated Outpatient Service Inpatient Department our hospital from March 2013 to December 2015 enrolled randomly divided into observation group control using a random number table. Both groups givensymptomatic including desensitization, given for 2 courses addition symptomatic...

10.3760/cma.j.issn.1001-9391.2017.02.015 article EN PubMed 2017-02-20
Coming Soon ...