A5003623694- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Neurological Disease Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Peripheral Artery Disease Management
- Intracranial Aneurysms: Treatment and Complications
- Neurological Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Migraine and Headache Studies
- Neurosurgical Procedures and Complications
- Neurological Complications and Syndromes
- Moyamoya disease diagnosis and treatment
- Advanced Neuroimaging Techniques and Applications
- Vestibular and auditory disorders
- Medical Imaging and Analysis
- Vascular Malformations Diagnosis and Treatment
- Cardiovascular and Diving-Related Complications
- Vitamin D Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Syphilis Diagnosis and Treatment
- Protein Kinase Regulation and GTPase Signaling
Arcadia
2024
Health and Education Research Management and Epidemiologic Services (United States)
2023
University of Massachusetts Chan Medical School
2007-2019
Richard Wolf (Germany)
2014-2019
University Hospital and Clinics
2018
Foothills Medical Centre
2018
UMass Memorial Health Care
2014-2018
Inserm
2018
Université Paris Cité
2018
Délégation Paris 5
2018
To identify patterns of clinical presentation, imaging findings, and etiologies in a cohort hospitalized patients with localized nontraumatic convexal subarachnoid hemorrhage.Twenty-nine consecutive atraumatic hemorrhage were identified using International Classification Diseases-9 code from 460 evaluated at our institution over course 5 years. Retrospective review patient medical records, neuroimaging studies, follow-up data was performed.There 16 women 13 men between the ages 29 87 Two...
Background and Purpose— Patients with a cardioembolic stroke (CES) have worse outcomes than patients other causes of stroke. Among CES, atrial fibrillation (AF) is common comorbidity. Mounting data indicate that AF may be related to pathogenesis beyond acute cerebral thromboembolism. We sought determine whether represents an independent risk factor for severity outcome among CES. Methods— retrospectively analyzed hemispheric CES included in academic medical center’s registry. was determined...
The presence of white-matter hyperintensities (WMHs) has been linked to intracerebral hemorrhage (ICH). We sought determine whether the severity WMHs influences hematoma growth and ICH volume.We retrospectively reviewed prospectively collected clinical, laboratory, radiologic data from 79 consecutive patients who had brain magnetic resonance imaging performed within 72 hours symptom onset. assessed on modified Scheltens scale logistic-regression analysis examine association between volume....
Objective High white matter hyperintensity (WMH) burden is commonly found on brain MRI among patients with atrial fibrillation (AF). However, whether the link between AF and WMH extends beyond a common vascular risk factor profile uncertain. We sought to determine relates distinct lesion pattern which may suggest specific underlying pathophysiological relationships. Methods retrospectively analysed cohort of consecutive presenting embolic stroke at an academic hospital tertiary referral...
Leukoaraiosis (LA) predominantly affects the subcortical white matter, but mounting evidence suggests an association with cortical microvascular dysfunction and potentially decreased ischemic tolerance. Thus, we sought to assess whether preexisting LA is predictive of infarct volume after middle cerebral artery branch occlusion it relates a worse outcome.We analyzed data from 117 consecutive patients as documented by admission computed tomography angiography. Baseline clinical, laboratory,...
<h3>BACKGROUND AND PURPOSE:</h3> Leukoaraiosis is a common finding among patients with ischemic stroke and has been associated poor outcomes. Our aim was to ascertain whether the severity of pre-existing leukoaraiosis outcome in acute who are treated endovascular therapy. <h3>MATERIALS METHODS:</h3> We retrospectively analyzed data from 129 consecutive, prospectively enrolled undergoing therapy at single tertiary care center between January 2006 August 2013. assessed as supratentorial white...
The subcellular location of the enzymes eicosanoid biosynthesis is critical for their co-ordinate action in generation leukotrienes and prostaglandins. This activity thought to occur predominantly at a perinuclear location. Whereas locations cytosolic phospholipase (PL) A<sub>2</sub> each pathway have been defined, distribution low molecular weight species PLA<sub>2</sub> has remained elusive because lack antibodies that distinguish among homologous family members. We prepared...
The National Institutes of Health Stroke Scale (NIHSS) awards higher deficit scores for infarcts in the dominant hemisphere when compared with otherwise similar nondominant hemisphere. This has been shown to adversely affect stroke recognition, therapeutic decisions, and outcome. However, factors modifying association between infarct side severity are incompletely understood. Thus, we sought determine whether age age-related leukoaraiosis alter relation NIHSS score volume infarction.We...
<b><i>Background:</i></b> A substantial proportion of ischemic strokes has no any identified underlying cause. Notably, the prevalence a patent foramen ovale (PFO) is increased in cryptogenic stroke (CS) populations, which may serve as conduit for paradoxical emboli originating from deep vein thrombosis (DVT) including pelvic veins. Yet, there are published guidelines assessment veins part workup and few studies have systematically investigated potential source CS...
Although it is generally thought that patients with distal middle cerebral artery (M2) occlusion have a favorable outcome, has previously been demonstrated substantial minority will poor outcome by 90 days. We sought to determine whether assessing the Alberta Stroke Program Early CT Score (ASPECTS) infarct location allows for identifying at risk 90-day outcome. retrospectively analyzed isolated acute M2 admitted single academic center between January 2010 and August 2012. Infarct regions...
The ABCD(2) score is increasingly being used to triage patients with transient ischemic attack (TIA). Whether the can predict need for in-hospital intervention (IHI), other than initiation of antiplatelets and statins, unknown.The ability IHI would strengthen rationale use it as a decision-making tool. We thus conducted this study investigate relationship between IHI.We analyzed prospectively collected data from consecutive TIA over 12 months. determined upon admission results evaluation,...
Factors influencing outcome after cerebral artery occlusion are not completely understood. Although it is well accepted that the site of arterial critically influences outcome, majority studies investigating this issue has focused on proximal large occlusion. To gain a better understanding factors distal occlusion, we sought to assess predictors following isolated M2 middle infarcts.We retrospectively analyzed patients with acute admitted single academic center from January 2010 August 2012....
Osteogenesis imperfecta is associated with susceptibility to connective tissue damage, including intracranial but usually extra-axial hemorrhage. Plasminogen activator inhibitor-1 deficiency a rare fibrinolytic cause of systemic bleeding diathesis.To describe case brainstem intraparenchymal hemorrhage and coagulation disorders.Case report.Academic medical center.A 36-year-old woman history osteogenesis presented the emergency department after an argument, during which she developed left ear...