A5049409252- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Renal cell carcinoma treatment
- Colorectal Cancer Treatments and Studies
- Ferroptosis and cancer prognosis
- Genetic factors in colorectal cancer
- Radiation Effects in Electronics
- Gastric Cancer Management and Outcomes
- Educational Technology in Learning
- Higher Education Teaching and Evaluation
- Graphite, nuclear technology, radiation studies
- Lung Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Engineering and Information Technology
- Extracellular vesicles in disease
- Colorectal and Anal Carcinomas
- Venous Thromboembolism Diagnosis and Management
- Lung Cancer Research Studies
- Ear and Head Tumors
- Educational Outcomes and Influences
- Pathogenesis and Treatment of Hiccups
- Cutaneous lymphoproliferative disorders research
- Pancreatic and Hepatic Oncology Research
- Diverse Applied Research Studies
- Educational Innovations and Technology
Hospital Universitario Quirónsalud Madrid
2022-2023
Hospital Universitario La Paz
2015-2019
Instituto Peruano de Energía Nuclear
2014
Next Generation Sequencing (NGS) panels are increasingly used in advanced patients with cancer to guide therapy. There is, however, controversy about when should these be used, and their impact on the clinical course.In an observational study of 139 having NGS test [from January 1st, 2017 December 30th, 2020, two hospitals (Hospital Universitario de La Princesa Hospital Quironsalud Madrid) from Spain], we evaluated whether course (progression-free survival, PFS) was influenced by drug-based...
Purpose: To explore the tumor proteome of patients diagnosed with localized clear cell renal cancer (ccRCC) and treated surgery. Material methods: A total 165 FFPE samples from ccRCC were analyzed using DIA-proteomics. Proteomics subtypes defined a consensus cluster algorithm (CCA) characterized by functional approach probabilistic graphical models survival analyses. Results: We identified quantified 3091 proteins, including 2026 high-confidence proteins. Two proteomics (CC1 CC2) CC proteins...
718 Background: mCRC is the 2º cause of death in world. Development targeted therapies has increased survival. The efficacy these drugs (such Bevacizumab and monoclonal antibodies against EGFR) depends on use genetic biomarkers such as KRAS NRAS. BRAF status acts prognostic factor. objective this study was to perform a mutational analysis KRAS/NRAS/BRAF cohort 326 Spanish patients, correlate findings with clinical factors. Methods: We analyzed by chip-array (Infiniti System, USA), NRAS using...
Introduction: Lynch syndrome (LS) is the most common cause of inherited colorectal cancer (CRC) and accounts for approximately 3 percent newly diagnosed cases CRC. an autosomal dominant disorder that caused by a germline mutation in one several DNA mismatch repair genes (MLH1, MSH2, MSH6 PMS2) or loss expression MSH2 due to deletion EPCAM gene (previously called TACSTD1). It characterized increased risk cancers endometrium, stomach, ovary, small bowel, hepatobiliary tract, urinary brain,...
e23007 Background: The aim of our study was to determine if an unscheduled hospitalization in advanced cancer patients is a good time for palliative care referrals, and this indicator could be improved with some other prognostic score. Methods: We conducted retrospective study, which included all the medical oncology service from January 2011 December 2013. In order improve accuracy analysis we considered only first admissions each patient. excluded scheduled unindicated hospitalization....
En este reporte se presentan los resultados obtenidos en el diseño y simulación de un sistema control utilizando estrategias avanzadas una celda producción la Planta Producción Radioisótopos del IPEN. Los demuestran que temperatura horno fusión estabiliza después 30 minutos, constituyéndose ventaja para obtener máximo rendimiento 131I; asimismo, ha diseñado controlador óptimo integral permite modelo matemático reproduzca con suficiente exactitud comportamiento proceso. Con final tratado...
Introduction: Colorectal cancer (CRC) is the most incident in Spain, according to Spanish Network of Cancer Registries (REDECAN) and second cause death by Spain. Although OS metastatic setting has increased 24-30 months, 5-year continues be less than 12%. The first line treatment are well defined; however, there few therapeutic options for those patients who have progressed these standard therapies. After progression treatment, only with approved specific indication Regorafenib Trifluridine...
Background: Pulmonary carcinoids are a very rare group of neoplasia. Typical the most frequent ones, with earlier onset than atypical carcinoids. There is no clear relationship smoke. Most indolent and carcinoid syndrome rare. In localized disease, surgery best choice. locally advanced radical radiotherapy can be considered. For metastatic systemic treatment somatostatin analogs, multi-kinase inhibitors or chemotherapy proposed. Methods: We conducted descriptive retrospective study including...