A5010736000- Reproductive Biology and Fertility
- Pluripotent Stem Cells Research
- Renal and related cancers
- COVID-19 and healthcare impacts
- Prenatal Screening and Diagnostics
- Pregnancy-related medical research
- Preterm Birth and Chorioamnionitis
- Diversity and Career in Medicine
- Hospital Admissions and Outcomes
- Microtubule and mitosis dynamics
- Telemedicine and Telehealth Implementation
- Hormonal Regulation and Hypertension
- Cardiac, Anesthesia and Surgical Outcomes
- Neonatal Respiratory Health Research
- Healthcare Policy and Management
- Medical and Health Sciences Research
- Growth Hormone and Insulin-like Growth Factors
- Healthcare Systems and Technology
- Innovations in Medical Education
- Bladder and Urothelial Cancer Treatments
- Pregnancy and preeclampsia studies
- Genomic variations and chromosomal abnormalities
- Pharmacology and Obesity Treatment
- Pharmacological Effects of Natural Compounds
- COVID-19 and Mental Health
Akita University
2016-2024
Akita University Hospital
2021-2022
This prospective study evaluated the accuracy of non-invasive preimplantation genetic testing for aneuploidy (niPGT-A) using cell-free DNA in spent culture medium, as well that (PGT-A) trophectoderm (TE) biopsy after culturing beyond implantation. Twenty frozen blastocysts donated by 12 patients who underwent IVF at our institution were investigated. Of these, 10 on day 5 and 6. Spent medium TE cells collected from each blastocyst thawing, embryos cultured vitro up to days. The outgrowths...
The aim of this study was to investigate neutrophil elastase (NE) in amniotic fluid as a potential marker for predicting pregnancy continuation.
The hatching of a blastocyst where the portions on inside and outside zona pellucida feature figure-of-eight shape is termed "8"-shaped hatching; this type has been reported to affect proper presentation inner cell mass (ICM) in both human mouse embryos. Here, our aim was investigate factors that ICM during hatching. We performed IVF by using B6D2F1 female mice ICR male mice, used 104 captured blastocysts. Embryos were maintained KSOM at 37°C 5% CO2, O2, 90% N2 environment, their growth...
Abstract Aim The Ministry of Health, Labour, and Welfare Japan proposed a regulation overtime work as reform in style. However, the may deteriorate quality medical services due to reduction training time. Thus, study aimed reveal perceptions terms generation gaps views on self‐training work, among members Society Obstetrics Gynecology (JSOG). Methods A web‐based, self‐administered questionnaire survey was conducted JSOG. In total, 1256 respondents were included analysis. Data collected age,...
Abstract Backgrounds In 2013, the total number of obstetrician‐gynecologists decreased. The Japanese Society Obstetrics and Gynecology established MIRAI Committee in 2015. Within Committee, Trainees (JTOG) was established; it comprised 20 promising young recommended from regions across Japan. office term is 2 years. Objective purpose this report to learn inform about results MIRAI's activities. Methods We surveyed trends new also matched each seminar participant with them. Result memberships...
In recent years, there has been an increase in noninvasive prenatal testing (NIPT), where maternal blood samples are used to extract fetal cell-free DNA. Despite this being offered several facilities urban areas, NIPT remains be scarcely unavailable rural areas. Moreover, is lacking information with regard how pregnant women areas perceive NIPT. Thus, study, we conducted a survey among who came our clinic for and examined their views on genetic counseling.A questionnaire was administered...
<title>Abstract</title> During human embryonic development, early cleavage-stage embryos are more susceptible to errors. Studies have shown that many problems occur during the first mitosis, such as direct cleavage, chromosome segregation errors, and multinucleation. However, mechanisms whereby these errors mitosis in remain unknown. To clarify this aspect, present study, we imaged discarded living two-pronuclear stage zygotes using fluorescent labeling confocal microscopy without...
<title>Abstract</title> During human embryonic development, early cleavage divisions are prone to errors, with abnormal division, non-segregation of chromosomes, and multinucleation often observed during the first mitosis. Some studies suggest that nuclear status at 2 cell stage does not affect blastocyst progression or implantation; however, chromosomal aneuploidy is linked 4-cell stage. We fluorescently labelled DNA microtubules in 21 blastomeres 2-cell embryos used confocal microscopy...
Objectives: To investigate the association between online activities and number of new obstetrics gynecology senior residents.Methods: A nationwide web-based, self-administered anonymous survey was conducted to recruitment clerkship during coronavirus disease 2019 pandemic.An questionnaire sent 576 training institutions in Japan December 21, 2020, January 31, 2021.Overall, 334 that gave valid responses were included (response rate: 58.0%).Multivariate logistic regression analysis examined...
Abstract Aim Obstetrics and gynecology (Ob/Gyn) training became compulsory for Japanese physician interns from April 2020 to improve medical competence in treating women's diseases. This study aims understand the Ob/Gyn needs of postgraduate year 1–2 physicians (interns) thereby efficiency. Methods was administered at facilities December 2019 February 2020. An original questionnaire used evaluate their assessment needs. In analyses, were categorized according whether they willing major...
Abstract Dynamic morphological changes in the chromosomes and cytoskeleton occur mammals including humans, during early embryonic development, abnormalities such as chromosomal aneuploidy when development does not proceed normally. In previous reports, behavior of DNA mammalian embryos has conventionally been visualized observed by injecting target molecule mRNA, with a fluorescent substance-expressing gene incorporated, into embryos. However, genetic information human embryo to induce...
Abstract Purpose Dynamic morphological changes in the chromosome and cytoskeleton occur mammals humans during early embryonic development, abnormalities such as chromosomal aneuploidy when development does not proceed normally. Visualization of intracellular organelles allows elucidation mammalian embryos. The behavior DNA embryos has conventionally been observed by injecting target molecule mRNAs, incorporating a fluorescent substance‐expressing gene, into In this study, we visualized...
Abstract Time-lapse incubators have become increasingly popular in assisted reproductive technology, allowing for the observation of developmental process, which may be useful selection human embryos suitable transplantation. Dynamic morphological changes chromosomes and cytoskeleton occur during early embryonic development, including humans, abnormalities such as chromosomal aneuploidy when development does not proceed normally. Chromosome cytoskeletal dynamics are difficult to observe with...
"Welcome to OBGYN World!" A novel recruitment event for medical students organized by the Japan Society of Obstetrics and Gynecology. Since 2012, number doctors in who specialize obstetrics gynecology has shown a decreasing trend. To increase majoring gynecology, Japanese Trainees Gynecology subcommittee developed new called Welcome World! (WOW!); aim this was focus on lower grades students. The present report describes content WOW! results post-event questionnaire administered participating...
Abstract Preterm labour (PTL) can be described as an inflammatory event. C-reactive protein (CRP) and Interleukin-6 (IL-6) are key members of the innate immune response that play major roles in inflammation. The main objective this case-control study was to determine association specific CRP IL-6 polymorphisms with PTL. carried out a total 31 Japanese women PTL 28 control normal pregnancy. Four SNPs gene (rs1800947, rs3091244, rs2794521, rs3093059) two (rs2097677 rs1800795) were genotyped...