A5078467243- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Osteoarthritis Treatment and Mechanisms
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Inflammatory mediators and NSAID effects
- Health and Medical Studies
- Vasculitis and related conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Otitis Media and Relapsing Polychondritis
- Chronic Lymphocytic Leukemia Research
- Medical Practices and Rehabilitation
- Biosimilars and Bioanalytical Methods
- Urticaria and Related Conditions
- Gout, Hyperuricemia, Uric Acid
- Orthopedic Surgery and Rehabilitation
- Lymphoma Diagnosis and Treatment
- Musculoskeletal synovial abnormalities and treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Monoclonal and Polyclonal Antibodies Research
- Clinical practice guidelines implementation
- Hepatitis C virus research
- Viral Infections and Immunology Research
- Health Systems, Economic Evaluations, Quality of Life
- Psoriasis: Treatment and Pathogenesis
Bio Forschung Austria
2018-2025
Karl Landsteiner Society
2009-2021
Universitätsklinikum St. Pölten
2021
Landesklinikum Korneuburg
2008-2020
University Clinic of Traumatology
2020
Medical University of Graz
2015-2017
University of Graz
2016
Rheumatology Consultants
2016
Government of Lower Austria
2006-2016
State Hospital
2009-2015
Objective To evaluate the efficacy, pharmacokinetics, immunogenicity, and safety of multiple infusions a chimeric monoclonal anti-tumor necrosis factor α antibody (cA2) (infliximab; Remicade, Centocor, Malvern, PA) given alone or in combination with low-dose methotrexate (MTX) rheumatoid arthritis (RA) patients. Methods In 26-week, double-blind, placebo-controlled, multicenter trial, 101 patients active RA exhibiting an incomplete response flare disease activity while receiving MTX were...
To develop evidence based recommendations for the management of hand osteoarthritis (OA).
Osteoarthritis (OA) is the most common joint disease encountered throughout Europe. A task force for EULAR Standing Committee Clinical Trials met in 1998 to determine methodological and logistical approach required development of evidence based guidelines treatment knee OA. The were restricted cover all currently available treatments OA diagnosed either clinically and/or radiographically affecting any compartment knee.The first stage was selection modalities be considered. second comprised a...
Objectives To agree terminology and to develop recommendations for the diagnosis of calcium pyrophosphate deposition (CPPD). Methods The European League Against Rheumatism (EULAR) CPPD Task Force, comprising 15 experts from 10 countries, agreed terms using a Delphi consensus approach. Evidence was systematically reviewed presented in sensitivity, specificity positive likelihood ratio (LR) support diagnosis; ORs were used association. Strength recommendation (SOR) assessed by EULAR visual...
<h3>Objectives:</h3> To develop evidence-based recommendations for the use of methotrexate in daily clinical practice rheumatic disorders. <h3>Methods:</h3> 751 rheumatologists from 17 countries participated 3E (Evidence, Expertise, Exchange) Initiative 2007–8 consisting three separate rounds discussions and Delphi votes. Ten questions concerning disorders were formulated. A systematic literature search Medline, Embase, Cochrane Library 2005–7 American College Rheumatology/European League...
Objectives To develop evidence-based recommendations for management of calcium pyrophosphate deposition (CPPD). Methods A multidisciplinary guideline development group 15 experts, representing 10 European countries, generated key propositions CPPD using a Delphi consensus approach. For each recommendation research evidence was searched systematically. Whenever possible, the effect size and number needed to treat efficacy RR or OR side effects were calculated individual treatment modalities....
Background JAK-inhibitors (JAKi), recently approved in rheumatoid arthritis (RA), have changed the landscape of treatment choices. We aimed to compare effectiveness four current second-line therapies RA with different modes action, since JAKi approval, an international collaboration 19 registers. Methods In this observational cohort study, patients initiating tumour necrosis factor inhibitors (TNFi), interleukin-6 (IL-6i), abatacept (ABA) or were included. compared these treatments terms...
<b>Objective:</b> To develop a composite score for measurement of disease activity in polymyalgia rheumatica (PMR) and assess its internal external validity. <b>Methods:</b> A PMR (AS) was designed assessed validity two patient cohorts: 57 international patients evaluated primarily development the PMR-AS at baseline, weeks 4 24; validation, 24 Austrian week 4, mean (SD) point 33.6 (24.5). The calculated as: CRP (mg/dl)+VAS p (0–10)+VAS ph (0–10)+(MST (min)×0.1)+EUL (3–0); Cronbach's α...
To compare the DAS28 (Disease Activity Score including a 28-joint count) values of rheumatoid arthritis (RA) and fibromyalgia (FM) patients, to establish whether high pain levels impaired mood influence values.DAS28 were calculated in 62 consecutive patients with RA 26 suffering from FM. Values for scores as well single items patient cohorts compared using Student's t-tests. evaluate item weighting internal consistency total score factor analysis was performed Cronbach's alpha calculated.RA...
The expanded therapeutic arsenal in rheumatoid arthritis (RA) raises new clinical questions. objective of this study is to compare the effectiveness cycling Janus kinase inhibitors (JAKi) with switching biologic disease-modifying antirheumatic drug (bDMARD) patients RA after failure first JAKi.This a nested cohort within data pooled from an international collaboration 17 national registries (JAK-pot collaboration). Data JAKi treatment and who were subsequently treated either second or bDMARD...
To develop evidence-based recommendations on how to investigate and follow-up undifferentiated peripheral inflammatory arthritis (UPIA).697 rheumatologists from 17 countries participated in the 3E (Evidence, Expertise, Exchange) Initiative of 2008-9 consisting three separate rounds discussions modified Delphi votes. In first round 10 clinical questions were selected. A bibliographic team systematically searched Medline, Embase, Cochrane Library ACR/EULAR 2007-2008 meeting abstracts. Relevant...
Rheumatoid arthritis of the craniocervical region by MR imaging: detection and characterization.M A Stiskal, Neuhold, D H Szolar, M Saeed, C Czerny, B Leeb, J Smolen CzembirekAudio Available | Share
To establish a questionnaire to quantify the extent of function and activities hand in patients with degenerative or inflammatory disease finger joints.One hundred seventy-two osteoarthritis (OA, n = 69) rheumatoid arthritis (RA, 103) completed new questionnaire, SACRAH, that included 23 visual analogue scales covering function, stiffness level pain. SACRAH scores may range from 0 100.Comparing all studied patients, there was no significant difference between OA RA (34 vs 32, not...