A5068152459- Mast cells and histamine
- Cytokine Signaling Pathways and Interactions
- Asthma and respiratory diseases
- IL-33, ST2, and ILC Pathways
- Urticaria and Related Conditions
- interferon and immune responses
- Immune Cell Function and Interaction
- Eosinophilic Esophagitis
- Vitamin D Research Studies
- Cancer-related Molecular Pathways
- Psoriasis: Treatment and Pathogenesis
- Oral microbiology and periodontitis research
- Cell Adhesion Molecules Research
- Periodontal Regeneration and Treatments
- Immune Response and Inflammation
- Adipose Tissue and Metabolism
- Inflammatory mediators and NSAID effects
- Vitamin C and Antioxidants Research
- Reproductive tract infections research
- Cancer, Stress, Anesthesia, and Immune Response
- Chemokine receptors and signaling
- Atrial Fibrillation Management and Outcomes
- Streptococcal Infections and Treatments
- Autism Spectrum Disorder Research
- Cancer, Lipids, and Metabolism
University of Chieti-Pescara
2016-2025
Tecnologie Avanzate (Italy)
2023
Saint Camillus International University of Health and Medical Sciences
2022
Ospedale SS. Annunziata
2016
University Foundation
2011
University Clinical Centre
2011
Art Research Centre of the Slovak Academy of Sciences
2011
University of L'Aquila
1991-2003
Columbia University
2002
University Medical Center
2001
We evaluated whether angiotensin II (Ang II) influenced intercellular adhesion molecule (ICAM)-1 expression by human vascular endothelial cells derived from umbilical cord veins (HUVECs) and plasma soluble ICAM-1 levels in vivo.Cultured HUVECs were incubated with Ang (from 10(-9) to 10(-6) mol/L) or without candesartan PD12319 (inhibitors of AT(1) AT(2) receptors, respectively) for various times up 4 hours. Total RNA was then extracted HUVECs, Northern blots probed a 1.9-kb cDNA fragment....
Abstract Deletions of the 13q14 chromosome region are associated with B-cell chronic lymphocytic leukemia (B-CLL) and several other types cancer, suggesting presence a tumor suppressor gene. In previous studies minimal deletion (MDR) was mapped to less than 300-kilobase (kb) interval bordered by markers 173a12-82 138G4/1.3R. For identification putative gene, entire MDR (approximately 347 kb) has been sequenced, transcribed regions have identified exon trapping, EST-based full-length...
SARS-CoV-2, also referred to as CoV-19, is an RNA virus which can cause severe acute respiratory diseases (COVID-19), with serious infection of the lower tract followed by bronchitis, pneumonia and fibrosis. The severity disease depends on efficiency immune system which, if it weak, cannot stem its symptoms. new CoV-19 spreads in population at a rate 0.8-3% more than normal flu mostly affects men, since genes are expressed X chromosome. If would spread higher incidence (over 10%), affect...
We have described earlier a gene cluster, including at least six interferon-activatable genes closely linked to the erythroid α spectrin locus and serum amyloid P-component on murine chromosome 1. Here, we report that sequences of three from cluster (the 201, 202, 204 genes) are very similar in segment extending 550 nucleotides upstream 3′ end transcription initiation region beyond first exon intron border (96% similarity between 202 89% 201 genes). This contains following two types...
IL-1 induces a significant number of metabolic and hematological changes. In experimental animals, treatments cause hypotension due to rapid reduction systemic blood pressure, reduced vascular resistance, increased heart rate leukocyte aggregations. causes endothelial dysfunction, the triggering factor which may be different nature including pathogen infection. This includes macrophage intervention protein permeability, can mediated by several factors cytokines arachidonic acid products....
Members of the suppressor cytokine signaling (SOCS) family molecules regulate activation signaling. Experimental evidence indicates that SOCS expression is induced by cytokines and pro-inflammatory stimuli controlled at both transcriptional post-transcriptional levels. proteins are unstable seem to be rapidly degraded proteasomal pathways. However, mechanisms which protein levels regulated remain unclear. Here, we show TRIM8/GERP, a RING finger protein, interacts with SOCS-1 in vitro andin...
The development of different types materials with application in practice dentistry is an area intense growth and research due to its importance oral health. Among the diverse currently used restoration or dentures, acrylic based resins have been widely employed. release toxic components changes on their physical mechanical properties actually represent a goal intensive research. In vivo analysis showed that surface roughness resin represents factor could stimulate bacteria colonization soft...