A5053367324- Viral-associated cancers and disorders
- Lymphoma Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Immune Cell Function and Interaction
- Mycobacterium research and diagnosis
- Diagnosis and treatment of tuberculosis
- Autophagy in Disease and Therapy
- Pneumocystis jirovecii pneumonia detection and treatment
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Epigenetics and DNA Methylation
- Alcohol Consumption and Health Effects
- Esophageal Cancer Research and Treatment
- Gastroesophageal reflux and treatments
- Endoplasmic Reticulum Stress and Disease
- Liver Disease Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Heme Oxygenase-1 and Carbon Monoxide
- Cytomegalovirus and herpesvirus research
- Lipid metabolism and disorders
- Apelin-related biomedical research
First Affiliated Hospital Zhejiang University
2025
Zhejiang University
2018-2024
Wenzhou Medical University
2017
Background/Aims: Acute lung injury (ALI) is induced by a variety of external and internal factors leads to acute progressive respiratory failure. Previous studies have shown that apelin-13 can decrease the LPS, but specific mechanism unclear. Therefore, mouse model cell were designed explore how alleviates caused LPS. Methods: The effect on LPS-induced structural damage was determined H&E staining wet/dry weight ratio. related inflammatory in BALF examined ELISA. apoptotic pathway NF-κB...
Background: The association between smoking dependence and the risk of developing Barrett’s esophagus remains unclear. This study aimed to investigate whether a causal relationship exists esophagus, using Mendelian randomization analysis. Methods: Two-sample analysis was conducted evaluate impact esophagus. Additionally, we applied summary data-based techniques combine information from genome-wide studies (GWAS) with expression quantitative trait locus methylation locus. Results:...
Abstract Emerging biologic subsets and new prognostic markers are significantly important for aggressive diffuse large B‐cell lymphoma (DLBCL). Nevertheless, the high cost of testing limits availability these tests in most hospitals, thus making judgment based on basic immunohistochemical testing, whole blood Epstein–Barr virus DNA (WBEBV) surveillance clinical features advantageous hospitals patients with poor medical conditions. We included 647 DLBCL treated our hospital from January 2009...
Objective The aim was to analyze genetic mutations in the rpoB gene of rifampin-resistant Mycobacterium tuberculosis isolates (RIF R -MTB) from Zhejiang, China. Methods We prospectively analyzed RIF -associated 13 rural areas Zhejiang. Isolates were subjected species identification, phenotype drug susceptibility testing (DST), DNA extraction, and sequencing. Results A total 103 identified by DST (22 only, 14 poly-drug resistant, 49 multidrug pre-extensively resistant [pre-XDR], 5 extensively...
Mycobacterium tuberculosis (MTB) is a causative agent of (TB) that causes death worldwide.MTB was subjected to phenotypic drug-susceptibility tests (DST), and drug-resistant genes were sequenced.Previously treated patients more likely have positive smear results exhibit drug resistance. New be mono SM-resistant less INH- RIF-resistant. The most common mutations katG (S315T), rpoB (S450L), rpsL (K43R), embB (M306V).The proportion mono-SM-resistant TB among new higher.
Abstract The relationship between plasma EBV-DNA load (PEDL) and Epstein-Barr virus (EBV)-encoded small RNA (EBER) during early treatment of lymphoma remains unclear. We explored discrepancies in PEDL variables associated with EBER, evaluated the consistency EBER qualitative analysis (qPEDL). Serial measurements were performed to determine dynamic changes lymphoma. As a result, median NHL-NKT was higher than that NHL-B, ENKTCL DLBCL, positive negative. Age, Ki-67 ≧ 80%, Bcl-2 p53 qPEDL...