- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Medical Imaging and Analysis
- Air Quality and Health Impacts
- Bone Metabolism and Diseases
- Climate Change and Health Impacts
- Physical Activity and Health
- Cardiovascular and exercise physiology
- Sports Performance and Training
- Neuroinflammation and Neurodegeneration Mechanisms
- Noise Effects and Management
- Spinal Cord Injury Research
- Pregnancy-related medical research
- Fungal Plant Pathogen Control
- Inflammatory mediators and NSAID effects
- Bone health and treatments
- Anesthesia and Pain Management
- Pain Mechanisms and Treatments
- Multiple Sclerosis Research Studies
- Evolution and Genetic Dynamics
Yuhuangding Hospital
2022-2024
Qingdao University
2022-2024
Ministry of Health and Welfare
2021
Shanghai Changzheng Hospital
2021
Beijing Sport University
2021
Kaohsiung Medical University
2021
Kaohsiung Medical University Chung-Ho Memorial Hospital
2021
Pingtung Hospital
2021
Novartis (United States)
2016
Dementia is one of the major causes disability and dependency among older people worldwide. Alz-heimer's disease (AD), most common cause dementia elderly, has great impact on health-care system developed nations. Several risk factors are suggestive an increased AD, including APOE-ε4, male, age, diabetes mellitus, hypertension, low social engagement. However, data AD progression limited. Air pollution revealed to be associated with increasing incidence, but relationship between air clinical...
Bone homeostasis has been a dynamic equilibrium between osteoclasts (OCs) and osteoblasts (OBs). However, excessive activation of OCs could disturb the bone homeostasis. As result, effective medical interventions for patients are greatly demanding. NO/guanylate cyclase (GC)/cGMP signaling cascade previously reported to regulate metabolism, GC plays significantly critical role. Vericiguat, as novel oral soluble guanylate (sGC) stimulator, firstly in 2020 treat with heart failure....
Objective. This present study aimed to explore the clinical effects of a novel capsule lumbar interbody fusion (CLIF) on foot drop due degenerative diseases. Methods. Between June 2018 and January 2019, total 27 patients admitted our department with diseases associated were prospectively enrolled. Given selection surgical technique, divided into traditional TLIF group CLIF group. We assessed patients’ neurological status using JOA VAS score, tibialis anterior muscle strength MMT diameter...
OBJECTIVE: To assess the durability of reduction in relapse rates among patients receiving long-term fingolimod therapy a real-world setting. BACKGROUND: Fingolimod was approved by FDA September 2010 as first oral disease-modifying (DMT) for relapsing-remitting multiple sclerosis (MS). DESIGN/METHODS: Patients diagnosed with MS who initiated (FTY) were identified from MarketScan database (1/1/2009-12/31/2014). Baseline patient characteristics assessed during 1-year prior to FTY initiation....
PURPOSE: The objective of the present study was to investigate effects 8-week high-intensity interval training (HIIT) on bone metabolism in sedentary college women. METHODS: Twenty-six healthy, female participants were randomly assigned into either HIIT (n = 13, age 23.2 ± 2.9 yr, weight 59.2 7.2 kg, height 162.9 3.3 cm; 90% VO2max run for 3 min interspersed with 40% 2 min, 6 bouts one session) or moderate-intensity continuous (MICT) group 21.9 1.7 59.3 6.6 160.9 4.4 60% 30 min) sessions per...
Abstract Background Traumatic spinal cord injury (SCI) causes severe motor dysfunction and persistent central neuropathic pain (Nep) that remains uncured yet. Programmed cell death ligand-1 (PD-L1) is typically produced by cancer cells contributes to the immune-suppressive in tumor microenvironment, role of PD-L1 regulating inflammatory response Nep after SCI unclear. A growing amount research has begun investigate effect on macrophages microglia. Considering pivotal macrophages/microglia...