Liyun He

ORCID: 0000-0002-2450-791X
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Research Areas
  • Diabetes Treatment and Management
  • Traditional Chinese Medicine Studies
  • Peptidase Inhibition and Analysis
  • Nutrition and Health in Aging
  • Metabolism, Diabetes, and Cancer
  • Acute Ischemic Stroke Management
  • Cerebral Palsy and Movement Disorders
  • Medical Research and Treatments
  • Dermatology and Skin Diseases
  • Nutritional Studies and Diet
  • Sleep and related disorders
  • Parathyroid Disorders and Treatments
  • Asthma and respiratory diseases
  • Telomeres, Telomerase, and Senescence
  • Neurological Disease Mechanisms and Treatments
  • Ginseng Biological Effects and Applications
  • Atrial Fibrillation Management and Outcomes
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Cancer Mechanisms and Therapy
  • Magnesium in Health and Disease
  • Allergic Rhinitis and Sensitization
  • Obesity, Physical Activity, Diet
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Diet and metabolism studies
  • Cardiovascular Health and Risk Factors

Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2025

Peking Union Medical College Hospital
2020-2025

Shenyang Pharmaceutical University
2025

Brigham and Women's Hospital
2025

Beijing Anzhen Hospital
2020-2024

Capital Medical University
2020-2024

Chenzhou First People's Hospital
2024

Chengdu Fifth People's Hospital
2024

China Academy of Chinese Medical Sciences
2023-2024

Academy of Medical Sciences
2023

Abstract Background To systematically analyze differences in atherosclerotic cardiovascular disease (ASCVD) burden between young and older adults. Methods We estimated the prevalence, mortality, disability-adjusted life years (DALYs) of ASCVD, including ischemic heart (IHD), stroke (IS), peripheral artery (PAD), individuals aged 20–54 > 55 from 1990–2019, utilizing data 2019 Global Burden Disease Study. The annual percentage changes (EAPCs) for age-specific or DALY rates were calculated...

10.1186/s12916-024-03527-4 article EN cc-by BMC Medicine 2024-07-19

Abstract Background The aim of this study was to evaluate the efficacy and safety acupuncture in treatment for allergic rhinitis. Methods This a multicenter, randomized, parallel‐controlled study. Participants were randomized either active acupuncture, sham or waitlist groups. groups received three times per week 4 weeks. In group, minimal at nonacupuncture points used. group did not receive any treatment. Results Of 238 participants, 97, 94, 47 individuals assigned respectively. After...

10.1111/all.12053 article EN other-oa Allergy 2012-12-18

Objectives: To determine how rates of discussion metabolic and bariatric surgery (MBS) between patients with class 2 obesity higher their healthcare providers as well subsequent progression to MBS have varied by race sex over the last 20 years. Background: Obesity is a growing public health crisis. remains most effective treatment for long-term management obesity. Methods: Retrospective cohort study electronic records from large tertiary academic system using previously validated natural...

10.1097/as9.0000000000000540 article EN cc-by-nc-nd Annals of Surgery Open 2025-01-15

Mental health issues like insomnia, anxiety, and depression have increased significantly. Artificial intelligence (AI) has shown promise in diagnosing providing personalized treatment. This study aims to systematically review the application of AI addressing depression, identifying key research hotspots, forecasting future trends through bibliometric analysis. We analyzed a total 875 articles from Web Science Core Collection (2000-2024) using tools such as VOSviewer CiteSpace. These were...

10.1177/20552076251324456 article EN cc-by-nc-nd Digital Health 2025-01-01

Experimental and epidemiological studies have indicated an association between diabetes exposure increased risk of liver cancer due to nonalcoholic steatohepatitis (NASH). However, date, no systematic study has specifically investigated the burden NASH-related high fasting plasma glucose (HFPG) levels worldwide.The number rate deaths disability-adjusted life years (DALYs) from HFPG-induced were estimated based on results 2019 Global Burden Disease Study. The annual percentage changes (EAPCs)...

10.1186/s13098-022-00976-w article EN cc-by Diabetology & Metabolic Syndrome 2023-01-17

Objective This study aimed to systematically evaluate the association between triceps skinfold (TSF) thickness (which indicates subcutaneous fat) mid‐arm muscle circumference (MAMC; which reflects mass), mid‐upper arm (MUAC), and all‐cause mortality. Methods A total of 17,717 adults from China Health Nutrition Survey (1993‐2015) were included. Cox proportional hazards models used calculate hazard ratios (HRs) 95% confidence intervals (CIs) for The joint effect TSF MAMC was examined, planned...

10.1002/oby.23179 article EN Obesity 2021-05-21

Abstract Background High fasting plasma glucose (HFPG) is the fastest-growing risk factor for cancer deaths worldwide. We reported mortality attributable to HFPG at global, regional, and national levels over past three decades associations with age, period, birth cohort. Methods Data this study were retrieved from Global Burden of Disease Study 2019, we used age-period-cohort modelling estimate cohort period effects, as well net drift (overall annual percentage change) local (annual change...

10.1186/s12889-023-16076-x article EN cc-by BMC Public Health 2023-07-15

Triptolide (TPL) is a main active compound isolated from Tripterygium wilfordii Hook f. Despite its positive therapeutic effect, the female reproductive toxicity of TPL still bottleneck clinical application. The study was designed to investigate adverse effects on mice ovary and underlying mechanism TPL. Adult NIH were treated with two doses (25 50 μg/kg/d) for days, respectively. Mice estrous cycle detected by vaginal cytology method. Half each group selected randomly perform...

10.1177/0960327116638725 article EN Human & Experimental Toxicology 2016-03-29

Background Body mass index (BMI) is a common indicator in clinical practice, but it not sufficient to predict insulin resistance (IR). Other anthropometric methods supplement BMI the assessment of body composition, which can be predicted more accurately. This cross-sectional study aimed evaluate association between mid-upper arm circumference (MUAC), triceps skinfold (TSF) thickness, mid-arm muscle (MAMC) and IR Chinese adults. Methods analyzed data from 2009 China Health Nutrition Survey...

10.3389/fendo.2022.1054671 article EN cc-by Frontiers in Endocrinology 2022-12-23

To evaluate the efficacy and safety of Xinfeng capsule in patients suffering rheumatoid arthritis (RA). A multi-center parallel-group designed, double-blind, randomized, controlled trial was conducted. Totally 304 RA were assigned to two groups: one group administered (XFC) plus placebo leflunomide other given (LEF) XFC for twelve weeks. The clinical laboratory parameters compared at baseline fourth, eighth, twelfth After twelve-week treatment, groups all showed some trend effectiveness when...

10.1016/s0254-6272(15)30130-8 article EN cc-by-nc-nd Deleted Journal 2015-10-01

High dietary magnesium intake may reduce insulin resistance (IR) and metabolic syndrome (MetS). The aim of the cross-sectional analysis was to evaluate association between intake, IR, MetS using data from China Health Nutrition Survey.Dietary defined as daily divided by body weight. Logistic regression used calculate odds ratio (OR) for IR prevalence across quartile categories intake. In addition, we macro PROCESS perform mediation analyses.A total 8120 participants were included in final...

10.2147/dmso.s257884 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2020-07-01

Hyperglycemia is a rapidly increasing risk factor for cancer mortality worldwide. However, the dose‒response relationship between glucose levels and all-cause in survivors still uncertain. We enrolled 4,491 (weighted population 19,465,739) from 1999–2019 National Health Nutrition Examination Survey (NHANES). Cancer were defined based on question of whether they had ever been diagnosed with by doctor or health professional. Hemoglobin A1c (HbA1c) was selected this study as stable marker...

10.1186/s12889-024-19545-z article EN cc-by-nc-nd BMC Public Health 2024-07-26

Diet can influence peripheral leukocyte telomere length (LTL), and various micronutrients have been reported to correlate with it. Zinc is known for its antioxidant properties immunomodulatory effects. However, there are few epidemiological investigations on the relationship between dietary zinc intake LTL. This study analyzed association LTL potential role of inflammation oxidative stress among them. Cross-sectional community-based study. 599 participants from rural communities in Changping...

10.1007/s12603-023-1992-z article EN cc-by-nc-nd The journal of nutrition health & aging 2023-09-01
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