David Dick

ORCID: 0000-0002-2453-2429
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About
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Research Areas
  • Medical Imaging Techniques and Applications
  • Radiopharmaceutical Chemistry and Applications
  • Service-Oriented Architecture and Web Services
  • Radiomics and Machine Learning in Medical Imaging
  • Neuroendocrine Tumor Research Advances
  • Big Data and Business Intelligence
  • Cystic Fibrosis Research Advances
  • Neuroblastoma Research and Treatments
  • Cloud Computing and Resource Management
  • Medical Imaging and Pathology Studies
  • Tracheal and airway disorders
  • Radiation Detection and Scintillator Technologies
  • Spinal Fractures and Fixation Techniques
  • Electromagnetic Fields and Biological Effects
  • Chemical Reactions and Isotopes
  • Neonatal Respiratory Health Research
  • Advanced MRI Techniques and Applications
  • Scoliosis diagnosis and treatment
  • Spine and Intervertebral Disc Pathology
  • Cancer, Hypoxia, and Metabolism
  • Particle Detector Development and Performance
  • Inhalation and Respiratory Drug Delivery
  • Lung Cancer Research Studies
  • Lanthanide and Transition Metal Complexes
  • Muon and positron interactions and applications

Technical University of Munich
2025

University of Iowa
2012-2024

Gesundheit Österreich
2024

University of Toledo
2002-2022

University of Iowa Hospitals and Clinics
2015-2021

Royal Victoria Hospital
2016-2018

University of Ulster
2016-2018

Stanford Medicine
2007-2013

Stanford University
2007-2012

University of Wisconsin–Madison
2003-2005

Abstract Speciation leads to adaptive changes in organ cellular physiology and creates challenges for studying rare cell-type functions that diverge between humans mice. Rare cystic fibrosis transmembrane conductance regulator (CFTR)-rich pulmonary ionocytes exist throughout the cartilaginous airways of 1,2 , but limited presence divergent biology proximal trachea mice has prevented use traditional transgenic models elucidate ionocyte airway. Here we describe creation conditional genetic...

10.1038/s41586-023-06549-9 article EN cc-by Nature 2023-09-20

<sup>18</sup>F-FDG PET/CT is used for detecting cancer and monitoring response to therapy. However, because of the variable rates glucose metabolism, not all cancers are identified reliably. Sodium <sup>18</sup>F was previously bone imaging can be as a skeletal tracer. The combined administration in single study detection has been reported date. <b>Methods:</b> This prospective pilot (November 2007–November 2008) 14 patients with proven malignancy (6 sarcoma, 3 prostate cancer, 2 breast 1...

10.2967/jnumed.108.058339 article EN Journal of Nuclear Medicine 2009-03-16

Objective The aim of this study was to compare 99mTc-MDP bone scanning, 18F NaF PET/CT, FDG and whole-body MRI (WBMRI) for detection known osseous metastases. Patients Methods This prospective pilot trial (September 2007-April 2009) enrolled 10 participants (5 men, 5 women, 47–81 years old) diagnosed with cancer WBMRI were performed within 1 month each participant. Results image quality evaluation extent disease superior by PET/CT compared scintigraphy in all patients skeletal lesions 3 the...

10.1097/rlu.0b013e3182815f64 article EN Clinical Nuclear Medicine 2013-03-02

<sup>18</sup>F-FDG PET/CT is used in a variety of cancers, but because variable rates glucose metabolism, not all cancers are reliably identified. <sup>18</sup>F<sup>−</sup> allows for the acquisition highly sensitive and specific images skeleton. We prospectively evaluated combined <sup>18</sup>F<sup>−</sup>/<sup>18</sup>F-FDG as single examination evaluation cancer patients compared it with separate scans. <b>Methods:</b> One hundred fifteen participants were enrolled an international...

10.2967/jnumed.112.108803 article EN Journal of Nuclear Medicine 2012-12-14

Background This study evaluates the influence and longevity of a microsurgery course on future careers medical students over period up to 10 years. The course, which has been well-established for 15 years, aimed impart fundamental microsurgical skills through practical exercises using non-biological biological models. Material methods was conducted as an anonymous online cross-sectional survey. Only who have completed training at our department within ten years between 2013 2023 were...

10.1055/a-2540-0917 article EN cc-by Journal of Reconstructive Microsurgery 2025-02-17

Localization of the site unknown primary tumor is critical for surgical treatment patients presenting with neuroendocrine (NET) metastases. <b>Methods:</b> Forty metastatic NET and underwent <sup>68</sup>Ga-DOTATOC PET/CT in a single-site prospective study. The was considered true-positive if positive confirmed by histology or follow-up imaging. scan false-positive no lesion found corresponding to <sup>68</sup>Ga-DOTATOC–positive site. All negative scans were false-negative. A classified...

10.2967/jnumed.116.180984 article EN Journal of Nuclear Medicine 2017-02-02

Abstract Objective The emergence of distraction‐based growing rods has provided the means to reduce progression spinal deformity in early onset scoliosis (EOS). current protocols for evaluating implants (ie, ASTM‐F1717 and ISO‐12189) were developed fusion/dynamic devices. These do not feature long unsupported rod lengths subjected distraction. Due unsuitability existing guidelines evaluation rods, a new finite element protocol is presented herein first time. Method A vertebrectomy (VO) model...

10.1002/jsp2.1119 article EN cc-by-nc-nd JOR Spine 2020-08-21

Yttrium-90 is widely used to label radiopharmaceuticals with curative, or at least palliative intent. At present, both the quantitative assay, /spl plusmn/10% variation, and in vivo imaging observe bremstrahllung from 2.3 MeV beta//sup -/. Detection of positron, which created E/sub 0/-decay 1.78 excited state a 34/spl plusmn/4 ppm branching ratio, are resolved two detector systems. A high purity Ge spectrometer calibrated efficiency clearly resolves 511 keV annihilation 2/1 peak over...

10.1109/nssmic.2004.1466619 article EN IEEE Symposium Conference Record Nuclear Science 2004. 2005-08-10

A biomechanical study to evaluate the effects of interspinous spacer under cyclic complex loading.To determine risk device migration and assess damage on specimen extreme coupled motion. Another objective was effect vertebral foramen canal dimensions after implantation.Interspinous spacers are a relatively new treatment option that clinically exposed loads. However, performance these has not been well characterized.Six human cadaveric motion segments were used for this study. The...

10.1615/jlongtermeffmedimplants.v18.i4.30 article EN Journal of Long-Term Effects of Medical Implants 2008-01-01

Patients with cystic fibrosis (CF) are at increased risk of nasal polyps. We present the case a 17-month-old Caucasian patient CF who presented hypertelorism causing cycloplegic astigmatism, right-sided mucoid discharge, snoring and noisy breathing. Imaging suggested bilateral mucoceles in ethmoid sinuses. Intraoperatively, soft tissue masses were noted, both posterior choanae patent. Polypectomy mega-antrostomies performed. Histological examination revealed inflammatory polyposis typical...

10.1136/bcr-2016-214467 article EN BMJ Case Reports 2016-06-21

ABSTRACT The use of gallium-68 for molecular imaging is gaining momentum world-wide. While our understanding 68 Ga chemistry, generators, and associated synthesis modules appear to have advanced a clinically-reliable stage, uncertainty in the supply radiopharmaceutically-suitable parent significant concern. In this work, we examine current Ge an effort better understand potential expansion manufacturing meet increasing demand Ga. Although specific information on sales highly business...

10.5005/jp-journals-10028-1053 article EN Journal of Postgraduate Medicine Education and Research 2013-01-01
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