A5048958791- Olfactory and Sensory Function Studies
- Pesticide Exposure and Toxicity
- Alcoholism and Thiamine Deficiency
- Adipose Tissue and Metabolism
- Stress Responses and Cortisol
- Coffee research and impacts
- Natural Compound Pharmacology Studies
- Synthesis of Organic Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Cannabis and Cannabinoid Research
- Medicinal Plant Extracts Effects
- Insect and Pesticide Research
- Dye analysis and toxicity
- Environmental Toxicology and Ecotoxicology
- Medicinal Plants and Neuroprotection
Universidade Federal de Ciências da Saúde de Porto Alegre
2020
Universidade Federal do Rio Grande do Sul
2015-2018
Abstract Garcinielliptone FC ( GFC ) is a polyisoprenylated benzophenone isolated from Platonia insignis Mart (Clusiaceae) with promising anticonvulsant properties. However, its safe use and other effects on the central nervous system require assessment. This study assessed toxicological of using comet assay micronucleus test in mice treated for 28 days. A behavioural model was employed to detect possible injuries system. Mice (2, 10 20 mg/kg; i.p.) daily days were submitted rotarod test,...
Passiflora incarnata L. (Passifloraceae) has been traditionally used for treatment of anxiety, insomnia, drug addiction, mild infections, and pain. The aim this study was to investigate the effect a commercial extract P. in analgesia induced by alcohol withdrawal syndrome rats. In addition, brain-derived neurotrophic factor interleukin-10 levels were evaluated prefrontal cortex, brainstem, hippocampus. Male adult rats received oral gavage: (1: water group) 19 days, 1 day interval (8 days);...
Considering that previous studies suggest pesticides may cause hearing disorders in humans, as well the lack of proving specific mechanisms injury and difficulty separating concomitant etiological factors damage, such noise vibration, it is important to develop using animal models elucidate effects exposure those substances isolated from other damage etiologies. To evaluate if a dichlorvos based organophosphorus insecticide induce ototoxicity. 36 male Wistar rats were assigned 3 groups (12...